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View article: Prevalence of skin and mucosal lesions in adults with <i>Mycoplasma pneumonia</i> infection: A cohort study
Prevalence of skin and mucosal lesions in adults with <i>Mycoplasma pneumonia</i> infection: A cohort study Open
View article: Autochthonous transmission of Trichophyton indotineae through sexual contact, France, 2024
Autochthonous transmission of Trichophyton indotineae through sexual contact, France, 2024 Open
Trichophyton indotineae is an emerging difficult to diagnose dermatophyte species associated with terbinafine resistance, which was initially described in South-Asian and Middle-Eastern countries. We report four cases of sexually transmitt…
View article: SARS-CoV-2 lineage-dependent temporal phylogenetic distribution and viral load in immunocompromised and immunocompetent individuals
SARS-CoV-2 lineage-dependent temporal phylogenetic distribution and viral load in immunocompromised and immunocompetent individuals Open
View article: sST2 is a key outcome biomarker in COVID-19: insights from discovery randomized trial
sST2 is a key outcome biomarker in COVID-19: insights from discovery randomized trial Open
View article: Vaccines and the risk of Guillain-Barré syndrome: A French pharmacovigilance analysis
Vaccines and the risk of Guillain-Barré syndrome: A French pharmacovigilance analysis Open
This study suggests that Guillain-Barré syndrome may be a rare but potentially severe adverse event that can occur in the first few weeks after vaccination whatever its nature. Even if a vaccine was injected in the weeks preceding the firs…
View article: Evaluation of High-Dose Isoniazid in Multidrug-Resistant Tuberculosis Treatment
Evaluation of High-Dose Isoniazid in Multidrug-Resistant Tuberculosis Treatment Open
High-dose isoniazid is recommended to treat multidrug-resistant tuberculosis (MDR TB). Among 958 MDR TB isolates identified in France during 2008-2022, 93.1% exhibited high-level isoniazid resistance, and molecular testing showed limited d…
View article: Evolution of Antiretroviral Strategies and Costs Over 2015-2022: The Real-Life Experience of an HIV Clinic in Paris, France
Evolution of Antiretroviral Strategies and Costs Over 2015-2022: The Real-Life Experience of an HIV Clinic in Paris, France Open
View article: Clearance of archived integrase strand transfer inhibitors resistance mutations in people with virologically suppressed HIV infection
Clearance of archived integrase strand transfer inhibitors resistance mutations in people with virologically suppressed HIV infection Open
Introduction We assessed the kinetics of the clearance of integrase strand transfer inhibitors resistance mutations (INSTIs-RMs) and associated factors from people living with HIV (PWH) displaying suppressed viral replication after virolog…
View article: Humoral response after mRNA COVID-19 primary vaccination and single booster dose in people living with HIV compared to controls: A French nationwide multicenter cohort study—ANRS0001s COV-POPART
Humoral response after mRNA COVID-19 primary vaccination and single booster dose in people living with HIV compared to controls: A French nationwide multicenter cohort study—ANRS0001s COV-POPART Open
PWH had high responses to primary mRNA COVID-19 vaccination. In those who received a booster dose after 6 months, the humoral response at 12 months increased to similar levels to controls, even in those with low CD4 counts at baseline.
View article: Whole blood transcriptome signature predicts severe forms of COVID-19: Results from the COVIDeF cohort study
Whole blood transcriptome signature predicts severe forms of COVID-19: Results from the COVIDeF cohort study Open
COVID-19 is associated with heterogeneous outcome. Early identification of a severe progression of the disease is essential to properly manage the patients and improve their outcome. Biomarkers reflecting an increased inflammatory response…
View article: Efficacy of oral 20-hydroxyecdysone (BIO101), a MAS receptor activator, in adults with severe COVID-19 (COVA): a randomized, placebo-controlled, phase 2/3 trial
Efficacy of oral 20-hydroxyecdysone (BIO101), a MAS receptor activator, in adults with severe COVID-19 (COVA): a randomized, placebo-controlled, phase 2/3 trial Open
View article: Correction: Expert Narrative Review of the Safety of Cladribine Tablets for the Management of Relapsing Multiple Sclerosis
Correction: Expert Narrative Review of the Safety of Cladribine Tablets for the Management of Relapsing Multiple Sclerosis Open
View article: Higher Levels of SARS-CoV-2 Genetic Variation in Immunocompromised Patients: A Retrospective Case-Control Study
Higher Levels of SARS-CoV-2 Genetic Variation in Immunocompromised Patients: A Retrospective Case-Control Study Open
Background A severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection lasts longer in immunocompromised hosts than in immunocompetent patients. Prolonged infection is associated with a higher probability of selection for nove…
View article: Use of covid-19 convalescent plasma to treat patients admitted to hospital for covid-19 with or without underlying immunodeficiency: open label, randomised clinical trial
Use of covid-19 convalescent plasma to treat patients admitted to hospital for covid-19 with or without underlying immunodeficiency: open label, randomised clinical trial Open
Objective To evaluate the efficacy of covid-19 convalescent plasma to treat patients admitted to hospital for moderate covid-19 disease with or without underlying immunodeficiency (CORIPLASM trial). Design Open label, randomised clinical t…
View article: Comparison between targeted and vaccinated populations during the mpox vaccination campaign in France
Comparison between targeted and vaccinated populations during the mpox vaccination campaign in France Open
View article: Expert Narrative Review of the Safety of Cladribine Tablets for the Management of Relapsing Multiple Sclerosis
Expert Narrative Review of the Safety of Cladribine Tablets for the Management of Relapsing Multiple Sclerosis Open
View article: Factors Associated With Genotypic Resistance and Outcome Among Solid Organ Transplant Recipients With Refractory Cytomegalovirus Infection
Factors Associated With Genotypic Resistance and Outcome Among Solid Organ Transplant Recipients With Refractory Cytomegalovirus Infection Open
Genotypically resistant cytomegalovirus (CMV) infection is associated with increased morbi-mortality. We herein aimed at understanding the factors that predict CMV genotypic resistance in refractory infections and disease in the SOTR (Soli…
View article: Hepatitis A, hepatitis B and HPV vaccine needs and coverage in MSM initiating HIV PrEP in a sexual health clinic in Paris
Hepatitis A, hepatitis B and HPV vaccine needs and coverage in MSM initiating HIV PrEP in a sexual health clinic in Paris Open
International audience
View article: Complement-dependent mpox-virus-neutralizing antibodies in infected and vaccinated individuals
Complement-dependent mpox-virus-neutralizing antibodies in infected and vaccinated individuals Open
View article: Complement-dependent mpox virus-neutralizing antibodies in infected and vaccinated individuals
Complement-dependent mpox virus-neutralizing antibodies in infected and vaccinated individuals Open
Mpox virus (MPXV) caused a multi-country outbreak in non-endemic areas in 2022. The Modified Vaccinia Ankara (MVA)-based vaccine was used as prophylaxis, but its effectiveness remains poorly characterized. Here, we developed two assays for…
View article: Vaccination contre le SARS-CoV-2 avant l’introduction d’un traitement par anti-CD20 chez les patients atteints de sclérose en plaques : une protection durable ?
Vaccination contre le SARS-CoV-2 avant l’introduction d’un traitement par anti-CD20 chez les patients atteints de sclérose en plaques : une protection durable ? Open
View article: Intermittent Bictegravir/Emtricitabine/Tenofovir Alafenamide Treatment Maintains High Level of Viral Suppression in Virally Suppressed People Living with HIV
Intermittent Bictegravir/Emtricitabine/Tenofovir Alafenamide Treatment Maintains High Level of Viral Suppression in Virally Suppressed People Living with HIV Open
In this observational study, we aimed to evaluate whether bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) administered 5 or 4 days a week is able to maintain viral suppression in people living with HIV (PLHIV). We enrolled 85 pat…
View article: Mpox in people with advanced HIV infection: a global case series
Mpox in people with advanced HIV infection: a global case series Open
View article: Specificities of Meningitis and Meningo-Encephalitis After Kidney Transplantation: A French Retrospective Cohort Study
Specificities of Meningitis and Meningo-Encephalitis After Kidney Transplantation: A French Retrospective Cohort Study Open
Kidney transplant recipients develop atypical infections in their epidemiology, presentation and outcome. Among these, meningitis and meningoencephalitis require urgent and adapted anti-infectious therapy, but published data is scarce in K…
View article: Oral 20-Hydroxyecdysone (BIO101), a MAS Receptor Activator,Reduces the Combined Proportion of Respiratory Failures or Early Deaths in Adults with Severe COVID-19. Findings of a Randomized, Placebo-Controlled, Phase 2/3 Trial (COVA)
Oral 20-Hydroxyecdysone (BIO101), a MAS Receptor Activator,Reduces the Combined Proportion of Respiratory Failures or Early Deaths in Adults with Severe COVID-19. Findings of a Randomized, Placebo-Controlled, Phase 2/3 Trial (COVA) Open
View article: Decrease in CD4 count and risk of severe morbidity in PWH with controlled viral load after initiating cART between 2006 and 2018
Decrease in CD4 count and risk of severe morbidity in PWH with controlled viral load after initiating cART between 2006 and 2018 Open
International audience
View article: Time to negative PCR conversion amongst high-risk patients with mild-to-moderate Omicron BA.1 and BA.2 COVID-19 treated with sotrovimab or nirmatrelvir
Time to negative PCR conversion amongst high-risk patients with mild-to-moderate Omicron BA.1 and BA.2 COVID-19 treated with sotrovimab or nirmatrelvir Open
View article: Anti-PD-1 immune-related adverse events are associated with high therapeutic antibody fixation on T cells
Anti-PD-1 immune-related adverse events are associated with high therapeutic antibody fixation on T cells Open
Immune checkpoint inhibitors (ICI) widely improved the treatment of solid and hematologic malignancies. Yet, a remarkable proportion of patients receiving ICI develop immune related adverse events (irAEs) which are difficult to define as t…
View article: Decrease in CD4 T-Cell Count and Risk of Severe Morbid Conditions in People With Human Immunodeficiency Virus Infection With Controlled Viral Load After Initiating Combination Antiretroviral Therapy Between 2006 and 2018
Decrease in CD4 T-Cell Count and Risk of Severe Morbid Conditions in People With Human Immunodeficiency Virus Infection With Controlled Viral Load After Initiating Combination Antiretroviral Therapy Between 2006 and 2018 Open
Background A previous study showed an association between CD4 T-cell count decline in people with human immunodeficiency virus infection (PWH) with viral suppression and an increased risk of severe morbid conditions. We aimed to assess the…
View article: Human monkeypox virus infection in women and non-binary individuals during the 2022 outbreaks: a global case series
Human monkeypox virus infection in women and non-binary individuals during the 2022 outbreaks: a global case series Open