Valery V. Tuchin
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View article: Next-generation biomedical sensing through photoacoustic–electrochemical synergy
Next-generation biomedical sensing through photoacoustic–electrochemical synergy Open
Modern biomedical sensing increasingly demands technologies capable of capturing structural, functional, and molecular information simultaneously. Photoacoustic (PA) and electrochemical (EC) sensing individually address these needs but exh…
View article: Computer-guided optical clearing for transcranial laser speckle imaging of cortical blood flow through synergistic tartrazine-induced cranial bone transparency
Computer-guided optical clearing for transcranial laser speckle imaging of cortical blood flow through synergistic tartrazine-induced cranial bone transparency Open
The clinical deployment of transcranial laser speckle-contrast imaging (LSCI) is limited by pronounced multiple scattering in cranial bone, which substantially reduces probing depth and distorts estimates of cerebral blood flow parameters.…
View article: Optical technologies in monitoring mobility and delivery of drugs and metabolic agents
Optical technologies in monitoring mobility and delivery of drugs and metabolic agents Open
View article: Parathyroid glands viability assessment and identification during surgery with multimodal diffuse reflectance spectroscopy and NIR autofluorescence probe
Parathyroid glands viability assessment and identification during surgery with multimodal diffuse reflectance spectroscopy and NIR autofluorescence probe Open
View article: Differences in the kinetics of optical clearing of healthy and diabetic head tissues
Differences in the kinetics of optical clearing of healthy and diabetic head tissues Open
Background and Objectives: Optical differentiation of pathologies is a promising tool for biomedical diagnostics, primarily due to its non-invasiveness and ease of implementation. The values of optical parameters andthe kinetics oftheir ch…
View article: Long-term investigation of 3D tissue detailed structure and multiparametric vascular network properties using OCT/OCTA for guiding atopic dermatitis theranostics
Long-term investigation of 3D tissue detailed structure and multiparametric vascular network properties using OCT/OCTA for guiding atopic dermatitis theranostics Open
View article: Depth-resolved imaging in turbid media via Mueller matrix polarimetry
Depth-resolved imaging in turbid media via Mueller matrix polarimetry Open
We preliminarily explore the feasibility of depth measurement using Mueller matrix polarimetry, establishing a method for tissue depth assessment while also expanding the applications of polarimetry.
View article: Fluorescence molecular tomography based on asymptotic source function approximation: Prospects for solving the problem
Fluorescence molecular tomography based on asymptotic source function approximation: Prospects for solving the problem Open
The paper is devoted to an original method of time-resolved fluorescence molecular tomography (FMT) based on asymptotic approximation to the fluorescence source function. Such an approximation helps to simplify the expressions that describ…
View article: Concept study on using fiber-optic sensors with nanocrystalline diamond sheet for tissue monitoring in radiotherapy
Concept study on using fiber-optic sensors with nanocrystalline diamond sheet for tissue monitoring in radiotherapy Open
Ionizing radiation plays a crucial role in medical diagnostics and therapy, particularly in cancer treatment. This paper presents a novel concept for real-time tissue monitoring during radiotherapy using fiber-optic sensors integrated with…
View article: Microstructured Waveguide Sensors for Point-of-Care Health Screening
Microstructured Waveguide Sensors for Point-of-Care Health Screening Open
Biosensor technologies in medicine, as in many other areas, are replacing labor-intensive methods of monitoring human health. This paper presents the results of experimental studies on label-free sensors based on a hollow core microstructu…
View article: Ex vivo model of using the method of optical skin clearing during antimicrobial photodynamic action
Ex vivo model of using the method of optical skin clearing during antimicrobial photodynamic action Open
This study evaluated the efficacy of transcutaneous photodynamic therapy using blue (428 nm) LED irradiation on Staphylococcus aureus 11 in combination with a water-soluble cationic pyridyl porphyrin and optical clearing agents (OCA) in an…
View article: Variation of optical properties of mouse brain using an optical clearing agent: experimental and simulation approaches
Variation of optical properties of mouse brain using an optical clearing agent: experimental and simulation approaches Open
For optical diagnosis and therapy in medicine, tracking changes in tissue refractive index (RI), absorption, and scattering coefficient is important. These characteristics may be measured using a variety of techniques. Examples of simulati…
View article: Microstructured Waveguide Sensors for Point-of-Care Health Screening
Microstructured Waveguide Sensors for Point-of-Care Health Screening Open
Biosensor technologies in medicine, as in many other areas, are replacing labor-intensive methods of monitoring human health. In this paper, the results of experimental studies of label-free sensors based on hollow-core microstructured opt…
View article: Molecular Diffusion and Optical Properties of Implantable Collagen Materials
Molecular Diffusion and Optical Properties of Implantable Collagen Materials Open
The effects of optical clearing of implantable collagen materials were studied using optical clearing agents (OCAs) based on aqueous glucose solutions of various concentrations. By measuring the kinetics of the collimated transmission spec…
View article: Effect of terahertz radiation on cells and cellular structures
Effect of terahertz radiation on cells and cellular structures Open
The paper presents the results of modern research on the effects of electromagnetic terahertz radiation in the frequency range 0.5–100 THz at different levels of power density and exposure time on the viability of normal and cancer cells. …
View article: Terahertz endoscopy of hard-to-access objects in the context of neoplasms diagnosis–A review
Terahertz endoscopy of hard-to-access objects in the context of neoplasms diagnosis–A review Open
View article: Polarization optical detection and localization of subcutaneous lesions
Polarization optical detection and localization of subcutaneous lesions Open
It is of great significance in clinical diagnosis and treatment evaluation to accurately identify the lesion tissue and further extract its characteristics and depth location. In this study, we construct tissue phantoms for three lesion ty…
View article: Modelling the effect of osmotic pressure on cancer cell growth: The role of area size and duration of exposure
Modelling the effect of osmotic pressure on cancer cell growth: The role of area size and duration of exposure Open
Background and Objectives: One of the new and effective methods for treating skin cancer and other proliferative diseases, such as psoriasis, is phototherapy, but there is a problem of limiting the penetration of radiation into the depths …
View article: On the 95th anniversary of the Honored Professor of Lomonosov Moscow State University Yuri Mikhailovich Romanovsky
On the 95th anniversary of the Honored Professor of Lomonosov Moscow State University Yuri Mikhailovich Romanovsky Open
View article: Depth-Resolved Imaging in Turbid Media via Polarimetry
Depth-Resolved Imaging in Turbid Media via Polarimetry Open
Accurately locating diseased tissue and determining its depth are essential for effective drug penetration and surgical treatments. This study focuses on determining tissue depth in turbid media using polar-imetry, specifically targeting f…
View article: Enhanced Optical Imaging of Proximal Human Interphalangeal Joints Using Skin Optical Clearing
Enhanced Optical Imaging of Proximal Human Interphalangeal Joints Using Skin Optical Clearing Open
View article: Polarization Optical Detection and Localization of Subcutaneous Lesions
Polarization Optical Detection and Localization of Subcutaneous Lesions Open
It is of great significance in clinical diagnosis and treatment evaluation to accurately identify the lesion tissue and further extract its characteristics and depth location. In this letter, we construct tissue phantoms for three lesion t…
View article: Influence of strain differences on resistance of Staphylococcus aureus to photodynamic action using meso-substituted cationic porphyrins
Influence of strain differences on resistance of Staphylococcus aureus to photodynamic action using meso-substituted cationic porphyrins Open
Background and Objectives. Infections associated with antibiotic-resistant strains of microorganisms, including Staphylococcus aureus, pose the greatest danger in nasopharyngeal diseases and post-surgical complications. A number of studies…
View article: Stereoscopic spatial graphical method of Mueller matrix: Global-Polarization Stokes Ellipsoid
Stereoscopic spatial graphical method of Mueller matrix: Global-Polarization Stokes Ellipsoid Open
A Mueller matrix covers all the polarization information of the measured sample, however the combination of its 16 elements is sometimes not intuitive enough to describe and identify the key characteristics of polarization changes. Within …
View article: Preface — Introduction to the Special Issue for Chinese-Russian Workshop on Biophotonics and Biomedical Optics
Preface — Introduction to the Special Issue for Chinese-Russian Workshop on Biophotonics and Biomedical Optics Open
View article: Discrimination of Optical Properties of Healthy and Cancerous Ovarian Tissue
Discrimination of Optical Properties of Healthy and Cancerous Ovarian Tissue Open
In this work, the optical properties of ovarian tissue of cats with histologically confirmed diagnoses: leimyosarcoma, stromal sarcoma, serous carcinoma, granulosa carcinoma, follicular phase (healthy) and luteal phase (healthy), in the op…
View article: Kinetics of glycerol-induced molecular diffusion in the normal and cancerous ovarian tissues
Kinetics of glycerol-induced molecular diffusion in the normal and cancerous ovarian tissues Open
Background and Objectives. There is a global trend towards an increase in the number of patients diagnosed with ovarian cancer during their reproductive years. One of the current clinical technologies is the technology of cryopreservation …
View article: Unpaired fundus image enhancement based on constrained generative adversarial networks
Unpaired fundus image enhancement based on constrained generative adversarial networks Open
Fundus photography (FP) is a crucial technique for diagnosing the progression of ocular and systemic diseases in clinical studies, with wide applications in early clinical screening and diagnosis. However, due to the non-uniform illuminati…
View article: 2nd Spring Biophotonics Conference in Porto
2nd Spring Biophotonics Conference in Porto Open
Following the success of the 1st Spring Biophotonics Conference in Porto [1], and in response to suggestions from numerous researchers advocating for regular exchanges of ideas, the 2nd Spring Biophotonics Conference was organized once aga…
View article: Quantification of attenuation and speckle features from endoscopic OCT images for the diagnosis of human brain glioma
Quantification of attenuation and speckle features from endoscopic OCT images for the diagnosis of human brain glioma Open