Explanipedia

Development and implementation of bedside ultrasound curriculum (BUS) for pediatric residents Open

S Snellgrove, Subramanyam N. Murthy, Mark D. Weber, KatieLynn Roman, Valmik Bhargava · 2024

Transpelvic Magnetic Stimulation Enhances Penile Microvascular Perfusion in a Rat Model: A Novel Interventional Strategy to Prevent Penile Fibrosis after Cavernosal Nerve Injury Open

Samuel Sorkhi, Christopher Cano Sanchez, Min Chul Cho, Sung Yong Cho, Hong Chung , et al. · 2022

TPMS is a novel and non-invasive intervention to improve penile MVP after CNI. Potential application includes treatment of ED and sexual function preservation following cancer treatment, possibly through improved penile hemodynamics that m…

Preclinical applications of high-definition manometry system to investigate pelvic floor muscle contribution to continence mechanisms in a rabbit model Open

Samuel Sorkhi, Young‐Jin Seo, Valmik Bhargava, Mahadevan Rajasekaran · 2021

We anticipate that with this new HDM technology, physiological changes within these orifices may be redefined using the extensive data that are generated from 96 sensors. When compared with conventional methods, HDM offers the advantages o…

The Bladder Microbiome Is Associated with Epithelial–Mesenchymal Transition in Muscle Invasive Urothelial Bladder Carcinoma Open

Wei Tse Li, Anjali Iyangar, Rohan G. Reddy, Jaideep Chakladar, Valmik Bhargava , et al. · 2021

The intra-tumor microbiome has recently been linked to epithelial–mesenchymal transition (EMT) in a number of cancers. However, the relationship between EMT and microbes in bladder cancer has not been explored. In this study, we profiled t…

Evaluation of Age- and Radical-Prostatectomy Related Changes in Male Pelvic Floor Anatomy Based on Magnetic Resonance Imaging and 3-Dimensional Reconstruction Open

Jesse W. Tai, Samuel Sorkhi, Ishika Trivedi, Kyoko Sakamoto, Michael Albo , et al. · 2020

This is perhaps the first 3-D reconstruction of male pelvic floor structures based on in-vivo MRI in healthy and symptomatic patients. Observed reduction in PRM and ICM thickness is possibly due to age-related atrophy.

MP84-03 CAVERNOSAL NERVE INJURY IMPAIRS PENILE MICROVASCULAR PERFUSION IN A RAT MODEL Open

Min Chul Cho, Samuel Sorkhi, Sung Yong Cho, Hong Chung, Christopher Cano Sanchez , et al. · 2020

You have accessJournal of UrologySexual Function/Dysfunction: Basic Research & Pathophysiology (MP84)1 Apr 2020MP84-03 CAVERNOSAL NERVE INJURY IMPAIRS PENILE MICROVASCULAR PERFUSION IN A RAT MODEL Min Chul Cho*, Samuel Sorkhi, Sung Yong Ch…

PD36-02 TRANSPELVIC MAGNETIC STIMULATION (TPMS) AS A NOVEL THERAPY TO ENHANCE VAGINAL MICROVASCULAR PERFUSION Open

Samuel Sorkhi, Min Cho, Sungyong Cho, Hong Chung, Christopher Cano Sanchez , et al. · 2020

You have accessJournal of UrologySexual Function/Dysfunction: Female (PD36)1 Apr 2020PD36-02 TRANSPELVIC MAGNETIC STIMULATION (TPMS) AS A NOVEL THERAPY TO ENHANCE VAGINAL MICROVASCULAR PERFUSION Samuel Sorkhi*, Minchul Cho, Sungyong Cho, H…

PD36-01 HYPOGASTRIC AND PELVIC NERVE CRUSH INJURY IMPAIRS VAGINAL MICROVASCULAR PERFUSION IN A RAT MODEL Open

Samuel Sorkhi, Min Chul Cho, Sung Yong Cho, Hong Chung, Christopher Cano Sanchez , et al. · 2020

You have accessJournal of UrologySexual Function/Dysfunction: Female (PD36)1 Apr 2020PD36-01 HYPOGASTRIC AND PELVIC NERVE CRUSH INJURY IMPAIRS VAGINAL MICROVASCULAR PERFUSION IN A RAT MODEL Samuel Sorkhi*, Min Chul Cho, Sung Yong Cho, Hong…

Sa1656 – Repetitive Transpelvic Magnetic Stimulation (TPMS) Attenuates Prolonged Vaginal Distension (VD) Induced Pelvic Microvascular Perfusion (MVP) Impairment Open

Mahadevan Rajasekaran, Hosong Yu, Abinav Chilukuri, Valmik Bhargava · 2019

MP55-02 REPEATED TRANSURETHRAL INTERVENTIONS INCREASE URETHRAL FIBROGENESIS AND STRICTURE SEVERITY IN A RABBIT MODEL Open

Mahadevan Rajasekaran, Hosong Yu, Seung-Mo Yuk, Raag Bhargava, Rucha Deshpande , et al. · 2019

You have accessJournal of UrologyTrauma/Reconstruction/Diversion: Urethral Reconstruction (including Stricture, Diverticulum) II (MP55)1 Apr 2019MP55-02 REPEATED TRANSURETHRAL INTERVENTIONS INCREASE URETHRAL FIBROGENESIS AND STRICTURE SEVE…

MP65-14 A NOVEL LASER SPECKLE CONTRAST IMAGING (LSCI) TECHNIQUE TO EVALUATE PENILE MICROCIRCULATORY DYSFUNCTION IN PATIENTS WITH PEYRONIE'S DISEASE Open

Aaron Bradshaw, Seung-Mo Yuk, Mahadevan Rajasekaran, Valmik Bhargava, Tung-Chin Hsieh · 2019

You have accessJournal of UrologySexual Function/Dysfunction: Peyronie’s Disease (MP65)1 Apr 2019MP65-14 A NOVEL LASER SPECKLE CONTRAST IMAGING (LSCI) TECHNIQUE TO EVALUATE PENILE MICROCIRCULATORY DYSFUNCTION IN PATIENTS WITH PEYRONIE'S DI…

PD21-08 ROLE OF GIV/GIRDIN AND INTEGRIN SIGNALING PATHWAYS IN URETHRAL STRICTURE FIBROGENESIS Open

Mahadevan Rajasekaran, Seung Ryeol Lee, Ki‐Ho Kim, Hosong Yu, Sarah Q. To , et al. · 2018

You have accessJournal of UrologyTrauma/Reconstruction/Diversion: Urethral Reconstruction (including Stricture, Diverticulum) I1 Apr 2018PD21-08 ROLE OF GIV/GIRDIN AND INTEGRIN SIGNALING PATHWAYS IN URETHRAL STRICTURE FIBROGENESIS M. Raj R…

MP43-16 TRANSPELVIC MAGNETIC STIMULATION (TPMS) AS A NOVEL THERAPY TO ENHANCE PENILE MICRO AND MACRO CIRCULATION Open

Ki-Ho Kim, Seung Ryeol Lee, Hosong Yu, Tung- Chin Hsieh, Valmik Bhargava , et al. · 2018

You have accessJournal of UrologySexual Function/Dysfunction: Basic Research & Pathophysiology I1 Apr 2018MP43-16 TRANSPELVIC MAGNETIC STIMULATION (TPMS) AS A NOVEL THERAPY TO ENHANCE PENILE MICRO AND MACRO CIRCULATION Ki-Ho Kim, Seung-Rye…

Exploration of male urethral sphincter complex using diffusion tensor imaging (DTI)‐based fiber‐tracking Open

Shantanu Sinha, Usha Sinha, Vadim Malis, Valmik Bhargava, Kyoko Sakamoto , et al. · 2018

Background Urinary incontinence is a major clinical problem arising primarily from age‐related degenerative changes to the sphincter muscles. However, the precise anatomy of the normal male sphincter muscles has yet to be established. Diff…

Characterization of age‐related penile microvascular hemodynamic impairment using laser speckle contrast imaging: possible role of increased fibrogenesis Open

Seung Ryeol Lee, Ki‐Ho Kim, Ho‐Song You, Johnny Fu, Tung‐Chin Hsieh , et al. · 2017

Current technology for penile hemodynamic evaluations in small animals is invasive and has limitations. We evaluated a novel laser speckle contrast imaging ( LSCI ) technique to determine age‐related changes in penile microvascular perfusi…

Altered Penile Caveolin Expression in Diabetes: Potential Role in Erectile Dysfunction Open

Jay Parikh, Alice E. Zemljic‐Harpf, Johnny Fu, Dimosthenis Giamouridis, Tung‐Chin Hsieh , et al. · 2017

Background The pathophysiology of increased severity of erectile dysfunction in men with diabetes and their poor response to oral pharmacotherapy are unclear. Defective vascular endothelium and consequent impairment in the formation and ac…

Age-related external anal sphincter muscle dysfunction and fibrosis: possible role of Wnt/β-catenin signaling pathways Open

Mahadevan Rajasekaran, Sadhana Kanoo, Johnny Fu, My‐Uyen Nguyen, Valmik Bhargava , et al. · 2017

Studies show an age-related increase in the prevalence of anal incontinence and sphincter muscle atrophy. The Wnt/β-catenin signaling pathway has been recently recognized as the major molecular pathway involved in age-related skeletal musc…

Wnt-β Catenin Signaling Pathway: A Major Player in the Injury Induced Fibrosis and Dysfunction of the External Anal Sphincter Open

Mahadevan Rajasekaran, Sadhana Kanoo, Johnny Fu, Valmik Bhargava, Ravinder K. Mittal · 2017

MP42-17 AGE RELATED URETHRAL SPHINCTER MUSCLE DYSFUNCTION AND FIBROSIS: POSSIBLE ROLE OF WNT SIGNALING PATHWAYS Open

Mahadevan Rajasekaran, Johnny Fu, My‐Uyen Nguyen, Valmik Bhargava · 2017

You have accessJournal of UrologyBladder & Urethra: Anatomy, Physiology & Pharmacology I1 Apr 2017MP42-17 AGE RELATED URETHRAL SPHINCTER MUSCLE DYSFUNCTION AND FIBROSIS: POSSIBLE ROLE OF WNT SIGNALING PATHWAYS M. Raj Rajasekaran, Johnny Fu…

Clinical Evaluation of Heart Failure: Agreement among Tests Open

Amit Kumar Pandey, William F. Penny, Valmik Bhargava, N. Chin Lai, Ronghui Xu , et al. · 2016

Methods commonly used clinically to assess cardiac function in patients with heart failure include ejection fraction (EF), exercise treadmill testing (ETT), and symptom evaluation. Although these approaches are useful in evaluating patient…

Intracoronary Gene Transfer of Adenylyl Cyclase 6 in Patients With Heart Failure Open

H. Kirk Hammond, William F. Penny, Jay H. Traverse, Timothy D. Henry, Matthew W. Watkins , et al. · 2016

clinicaltrials.gov Identifier: NCT00787059.

MP89-10 CAVEOLIN REGULATION OF PENILE HEMODYNAMICS: POSSIBLE ROLE IN ERECTILE DYSFUNCTION Open

Jay Parikh, Dimosthenis Giamouridis, Tung-Chin Hsieh, Jan M. Schilling, Valmik Bhargava , et al. · 2016

You have accessJournal of UrologySexual Function/Dysfunction: Basic Research & Pathophysiology II1 Apr 2016MP89-10 CAVEOLIN REGULATION OF PENILE HEMODYNAMICS: POSSIBLE ROLE IN ERECTILE DYSFUNCTION Jay Parikh, Dimosthenis Giamouridis, Tung-…

MP89-19 ALTERED CAVEOLIN EXPRESSION IN DIABETIC PENIS: POSSIBLE ROLE IN ERECTILE DYSFUNCTION Open

Mahadevan Rajasekaran, Johnny Fu, Adam Kassan, Alice E. Zemljic‐Harpf, Valmik Bhargava , et al. · 2016

You have accessJournal of UrologySexual Function/Dysfunction: Basic Research & Pathophysiology II1 Apr 2016MP89-19 ALTERED CAVEOLIN EXPRESSION IN DIABETIC PENIS: POSSIBLE ROLE IN ERECTILE DYSFUNCTION M. Raj Rajasekaran, Johnny Fu, Adam Kas…

Circular and longitudinal muscles shortening indicates sliding patterns during peristalsis and transient lower esophageal sphincter relaxation Open

Nirali Patel, Yanfen Jiang, Ravinder K. Mittal, Tae Ho Kim, Melissa M. Ledgerwood , et al. · 2015

Esophageal axial shortening is caused by longitudinal muscle (LM) contraction, but circular muscle (CM) may also contribute to axial shortening because of its spiral morphology. The goal of our study was to show patterns of contraction of …

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