Vanessa Boll
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View article: Reprogramming of bacterial virulence by lysine acetylation
Reprogramming of bacterial virulence by lysine acetylation Open
Gram-negative bacteria use a plethora of virulence factors to infect eukaryotic cells. CE-clan protease-related virulence factors were reported to act as deubiquitinases/ubiquitin-like specific proteases. Some have an additional acetyltran…
View article: Identification and characterization of a ubiquitin E3 RING ligase of the<i>Chlamydia</i>-like bacterium<i>Simkania negevensis</i>
Identification and characterization of a ubiquitin E3 RING ligase of the<i>Chlamydia</i>-like bacterium<i>Simkania negevensis</i> Open
In the arms race between a pathogen and the host, many bacteria have acquired a sizable armory to counteract or change the defense mechanisms of the host cell, including the eukaryotic ubiquitin system. Simkania negevensis , an obligate in…
View article: Functional and structural diversity in deubiquitinases of the Chlamydia-like bacterium Simkania negevensis
Functional and structural diversity in deubiquitinases of the Chlamydia-like bacterium Simkania negevensis Open
View article: Unexpected functional and structural diversity in deubiquitinases of the Chlamydia-like bacterium Simkania negevensis
Unexpected functional and structural diversity in deubiquitinases of the Chlamydia-like bacterium Simkania negevensis Open
Besides the regulation of many cellular pathways, ubiquitination is important for the defence against invading pathogens. Some intracellular bacteria have evolved deubiquitinase (DUB) effector proteins, which interfere with the host ubiqui…
View article: Characterization of <i>spa</i> mutants in the moss <i>Physcomitrella</i> provides evidence for functional divergence of <i><scp>SPA</scp></i> genes during the evolution of land plants
Characterization of <i>spa</i> mutants in the moss <i>Physcomitrella</i> provides evidence for functional divergence of <i><span>SPA</span></i> genes during the evolution of land plants Open
Summary The Arabidopsis COP 1/ SPA complex is a key repressor of photomorphogenesis that suppresses light signaling in the dark. Both COP 1 and SPA proteins are essential components of this complex. Although COP 1 also exists in humans, SP…