Explanipedia

7T MRI quantitative susceptibility mapping for magnetic resonance-guided focused ultrasound thalamotomy: methodology and anatomo-clinical correlations in a retrospective pilot study Open

Daniele Botta, Martin Ndengera, Masiel Velarde, P Guillemin, Christo Bratanov , et al. · 2025

Sensitivity to somatomotor conflicts links frontal subcortical dysfunction and minor hallucinations in Parkinson’s disease Open

Jevita Potheegadoo, Lea Duong Phan Thanh, Marie Elise Maradan‐Gachet, Cyrille Stucker, Nathalie H. Meyer , et al. · 2025

Background Minor hallucinations (MH) affect 30-60% of patients with Parkinson’s disease (PD), and are considered precursors to structured visual hallucinations and cognitive decline. While the link between structured visual hallucinations …

Subthalamic nucleus encoding steers adaptive therapies for gait in Parkinson’s disease Open

Stefano Scafa, Valeria de Seta, Ruijia Wang, P.A. Lopez, Camille Varescon , et al. · 2025

Parkinson’s disease leads to a spectrum of cardinal motor symptoms and locomotor deficits that vary in severity with the nature of daily activities and the fluctuating physiology of patients. Many of these deficits remain inadequately addr…

The Unseen Burden: Uncovering Shame and Its Determinants in Parkinson's Disease Open

Sabina Catalano Chiuvé, Damien Benis, Charline Rime, María João Forjaz, Paul Krack , et al. · 2025

Background Shame is frequent in Parkinson's disease (PD) and often overlooked. Objective The aim was to assess factors associated with PD‐related shame. Methods PD‐related shame was measured using the Shame and Embarrassment in PD (SPARK) …

Using the Tissue Impulse Response Function to Streamline Fractionated MRgFUS-Induced Hyperthermia Open

P Guillemin, Yacine M’Rad, G. Dipasquale, Orane Lorton, Vanessa Fleury , et al. · 2025

Background/Objectives: Combining radiation therapy with mild hyperthermia, especially via magnetic resonance-guided focused ultrasound (MRgFUS), holds promise for enhancing tumor control and alleviating symptoms in cancer patients. However…

Psilocybin-assisted psychotherapy for Parkinson's disease without depression: A case-report Open

Vanessa Fleury, Emilie Tomkova, Sabina Catalano Chiuvé, Louise Penzenstadler · 2025

Background Psychedelic assisted psychotherapy (PAP) can improve treatment-resistant depression. Its usefulness in Parkinson's disease (PD) is unknown. PD patients may have problems adjusting to their chronic progressive neurological diseas…

Neurology of Aging: Adapting Neurology Provision for an Aging Population Open

Patrick Stancu, Lisa Hentsch, Margitta Seeck, Dina Zekry, Christophe Graf , et al. · 2024

Background: Over the past few decades, advances in the neurology of aging have been considerable and have led to a better understanding of the science of age-related neurological disorders. Likewise, it changed the perception of classical …

La transplantation de microbiote fécal dans la maladie de Parkinson Open

Mathilde d’Esneval, Mayté Castro Jiménez, Ines Debove, Selma Aybek, Vanessa Fleury · 2024

Fäkale Mikrobiota-Transplantation bei Morbus Parkinson Open

Mathilde d’Esneval, Mayté Castro Jiménez, Ines Debove, Selma Aybek, Vanessa Fleury · 2024

Electroencephalographic Abnormalities in a Patient Suffering from Long-Term Neuropsychological Complications following SARS-CoV-2 Infection Open

Damien Benis, Philippe Voruz, Sabina Catalano Chiuvé, Valentina Garibotto, Frédéric Assal , et al. · 2023

Introduction: Emotional apathy has recently been identified as a common symptom of long COVID. While recent meta-analyses have demonstrated generalized EEG slowing with the emergence of delta rhythms in patients hospitalized …

Validation of Lead-DBS β-Oscillation Localization with Directional Electrodes Open

Colette Boëx, Abdullah Al Awadhi, Rémi Tyrand, Marco V. Corniola, Astrid Kibleur , et al. · 2023

In deep brain stimulation (DBS) studies in patients with Parkinson’s disease, the Lead-DBS toolbox allows the reconstruction of the location of β-oscillations in the subthalamic nucleus (STN) using Vercise Cartesia directional electrodes (…

Validation of Lead-DBS β-oscillation Localization with Directional Electrodes Open

Colette Boëx, Abdullah Al Awadhi, Rémi Tyrand, Marco V. Corniola, Astrid Kibleur , et al. · 2023

The Lead-DBS imaging toolbox reconstructs the location of β-oscillations in the subthalamic nucleus (STN) in patients with Parkinson’s disease. The objective was to compare this probabilistic location with those of intraoperativ…

Oral and intestinal dysbiosis in Parkinson's disease Open

E. Berthouzoz, Vladimir Lazarević, Alkisti Zekeridou, Mayté Castro Jiménez, Ines Debove , et al. · 2023

Supplementary Material for: Electroencephalographic abnormalities in a patient suffering from long-term neuropsychological complications following SARS-Cov2 infection Open

Damien Benis, Philippe Voruz, Chiuve S.C., Valentina Garibotto, Frédéric Assal , et al. · 2023

Introduction Emotional apathy has recently been identified as a common symptom of long COVID. While recent meta-analyses have demonstrated generalized EEG slowing with the emergence of delta rhythms in patients hospitalized for severe SARS…

Supplementary Material for: Successful MRI-guided focused ultrasound thalamotomy after ipsilateral Gamma Knife radiosurgery for essential tremor: a case report with video Open

Vanessa Fleury, David Romascano, Dietmar Schneider, Constantin Tuleasca, Orane Lorton , et al. · 2023

We report the case of a 67-year-old left-handed female patient with disabling medically-refractory essential tremor who underwent successful right-sided Magnetic Resonance-guided focused ultrasound (MRgFUS) of the ventral intermediate (VIM…

Successful MRI-Guided Focused Ultrasound Thalamotomy after Ipsilateral Gamma Knife Radiosurgery for Essential Tremor: A Case Report with Video Open

Vanessa Fleury, David Romascano, Damien Schneider, Constantin Tuleasca, Orane Lorton , et al. · 2023

We report the case of a 67-year-old left-handed female patient with disabling medically refractory essential tremor who underwent successful right-sided magnetic resonance-guided focused ultrasound (MRgFUS) of the ventral intermediate nucl…

Place de l’imagerie moléculaire dans la prise en charge du cancer de la prostate Open

Caroline Rousseau, Maëlle Le Thiec, Bruno Maucherat, Mathieu Frindel, Vanessa Fleury · 2021

Oral Dysbiosis and Inflammation in Parkinson’s Disease Open

Vanessa Fleury, Alkisti Zekeridou, Vladimir Lazarević, Nadia Gaïa, Catherine Giannopoulou , et al. · 2021

Background: Oral microbiota has largely escaped attention in Parkinson’s disease (PD), despite its pivotal role in maintaining oral and systemic health. Objective: The aim of our study was to examine the composition of the oral microbiota …

Geospatial analysis of individual-based Parkinson's disease data supports a link with air pollution: A case-control study Open

Vanessa Fleury, Rebecca Himsl, Stéphane Joost, Nicolas Nicastro, Matthieu Béreau , et al. · 2021

Embarrassment and Shame in People With Parkinson's Disease: A New Tool for Self-Assessment Open

Vanessa Fleury, Sabina Catalano Chiuvé, María João Forjaz, Mariagrazia Di Marco, Maria Messe , et al. · 2020

Shame and embarrassment related to Parkinson's disease (PD) are rarely addressed in clinical practice nor studied in neuroscience research, partly because no specific tool exists to detect them in PD. Objective: To develop a self-ap…

Extrastriatal 123I-FP-CIT SPECT impairment in degenerative parkinsonisms Open

Nicolas Nicastro, Vanessa Fleury, Nicolas Broc, Pierre R. Burkhard, Valentina Garibotto · 2020

This study provides evidence of a major extrastriatal ¹²³I-FP-CIT impairment, and therefore of an altered serotonergic transmission in PD and APS, confirming previous neuropathological and SERT imaging findings.

Modeling of Electric Fields in Individual Imaging Atlas for Capsular Threshold Prediction of Deep Brain Stimulation in Parkinson's Disease: A Pilot Study Open

Matthieu Béreau, Astrid Kibleur, Walid Bouthour, Emilie Tomkova Chaoui, Nicholas Maling , et al. · 2020

Background: Modeling of deep brain stimulation electric fields and anatomy-based software might improve post-operative management of patients with Parkinson's disease (PD) who have benefitted from subthalamic nucleus deep brain stim…

Shame in Parkinson’S Disease: A Review Open

Julio Angulo, Vanessa Fleury, Julie Péron, Louise Penzenstadler, Daniele Zullino , et al. · 2019

Shame is a self-conscious emotion marked by an intensely negative self-evaluation. It is exhibited by an individual upon realizing that she/he has violated an important (usually social) norm. Shame can be a source of emotional distress lea…

Classification of degenerative parkinsonism subtypes by support-vector-machine analysis and striatal 123I-FP-CIT indices Open

Nicolas Nicastro, Jennifer Wegrzyk, Maria Giulia Preti, Vanessa Fleury, Dimitri Van De Ville , et al. · 2019

OBJECTIVES: To provide an automated classification method for degenerative parkinsonian syndromes (PS) based on semiquantitative 123I-FP-CIT SPECT striatal indices and support-vector-machine (SVM) analysis. METHODS: 123I-FP-CIT SPECT was p…

First results of molecular imaging (FDG and FES) in prospective study for selecting second line hormonotherapy in estrogen receptors positive metastatic breast cancer patients Open

Bruno Maucherat, A. Leduc-Pennec, Normand Fleury, Ludovic Ferrer, Emmanuelle Bourbouloux , et al. · 2019

Localization of Deep Brain Stimulation Contacts Using Corticospinal/Corticobulbar Tracts Stimulation Open

Julien F. Bally, María Isabel Vargas, Judit Horváth, Vanessa Fleury, Pierre R. Burkhard , et al. · 2017

The correlation between electrode distance to the CSBT and contraction thresholds was found better when estimated with currents rather than voltage, eliminating the variance due to electrode impedance. Using LFS did not improve the precisi…

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