Vanessa Richartz
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View article: Benchmark of screening markers for KEAP1/NFE2L2 mutations and joint analysis with the K1N2-score
Benchmark of screening markers for KEAP1/NFE2L2 mutations and joint analysis with the K1N2-score Open
View article: Integrative genomic analyses of European intrahepatic cholangiocarcinoma: Novel <i>ROS1</i> fusion gene and PBX1 as prognostic marker
Integrative genomic analyses of European intrahepatic cholangiocarcinoma: Novel <i>ROS1</i> fusion gene and PBX1 as prognostic marker Open
Background Cholangiocarcinoma (CCA) is a fatal cancer of the bile duct with a poor prognosis owing to limited therapeutic options. The incidence of intrahepatic CCA (iCCA) is increasing worldwide, and its molecular basis is emerging. Envir…
View article: KEAP1/NFE2L2 Pathway Signature Outperforms KEAP1/NFE2L2 Mutation Status and Reveals Alternative Pathway-Activating Mutations in NSCLC
KEAP1/NFE2L2 Pathway Signature Outperforms KEAP1/NFE2L2 Mutation Status and Reveals Alternative Pathway-Activating Mutations in NSCLC Open
The K1N2-score identified KEAP1/NFE2L2-activated NSCLC by robustly detecting KEAP1/NFE2L2mut cases and discovering alternative genomic activators. It is a potential means for selecting patients with a constitutively active KEAP1/NFE2L2 pat…