Varsha Shukla
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View article: Novel Antimicrobial Peptides Derived from Urease-2 of Jack Beans for Treatment of Indian Priority Pathogens
Novel Antimicrobial Peptides Derived from Urease-2 of Jack Beans for Treatment of Indian Priority Pathogens Open
Antimicrobial peptides (AMPs) are short-chain amino acid sequences that play crucial roles in the host immune response. Canavalia ensiformis, commonly known as the jack bean, has long been recognized as a valuable protein source for bioche…
View article: Standardization of Portable Culture Device for Detection of Listeria Monocytogenes from Food Samples
Standardization of Portable Culture Device for Detection of Listeria Monocytogenes from Food Samples Open
Pathogens emerge and spread from a variety of sources including food, water, air, and clinical samples, resulting in disease epidemics in the community. The early detection of pathogens in food and water samples can help prevent illness tr…
View article: A novel method of testing the antimicrobial potentials of<i>Exiguobacterium aurantiacum, Lysinibacillus boronitolerans</i>and<i>Bacillus megaterium</i>
A novel method of testing the antimicrobial potentials of<i>Exiguobacterium aurantiacum, Lysinibacillus boronitolerans</i>and<i>Bacillus megaterium</i> Open
Microorganisms can be an effective source for antimicrobial compounds including peptides that provide an evolutionary advantage to them in specific niches. Prior studies have noted the antimicrobial properties of Exiguobacterium aurantiacu…
View article: Inter-observer Reliability in Reporting Complications of Transurethral Resection of the Prostate with Clavien-Dindo Classification: A Retrospective Observational Study
Inter-observer Reliability in Reporting Complications of Transurethral Resection of the Prostate with Clavien-Dindo Classification: A Retrospective Observational Study Open
Introduction: Transurethral Resection of the Prostate (TURP) is a gold standard treatment for Benign Prostatic Hyperplasia (BPH). The Clavien classification system was proposed in 1992 to grade complications of general surgery, which was t…
View article: CHASING THE RETENTION: EXAMINING THE DIVERSE EFFECTS OF JOB SATISFACTION AND WORK ENVIRONMENT ON EMPLOYEE RETENTION IN THE INFORMATION TECHNOLOGY SECTOR
CHASING THE RETENTION: EXAMINING THE DIVERSE EFFECTS OF JOB SATISFACTION AND WORK ENVIRONMENT ON EMPLOYEE RETENTION IN THE INFORMATION TECHNOLOGY SECTOR Open
In this study, we investigate employee retention in the dynamic IT sector in India, employing an exploratory research approach. Our research included 110 participants from various organizational levels, encompassing both established…
View article: Pharmaceutico-Analytical study of Shadbindu taila
Pharmaceutico-Analytical study of Shadbindu taila Open
Introduction: Shadbindu taila is an Ayurvedic herbo-mineral preparation used in a variety of clinical conditions especially in diseases of upper part of body. This taila is described as exceptionally beneficial for improving the strength o…
View article: Pharmacognostic and Analytical Profile of Leaves of Erythroxylum Moonii Hochr. – An Ethno-Medicinal Plant
Pharmacognostic and Analytical Profile of Leaves of Erythroxylum Moonii Hochr. – An Ethno-Medicinal Plant Open
Erythroxylum moonii Hochr. is a shrub or small tree in family Erythroxylaceae and folklore claims report the use of its leaves in the treatment of helminthiasis. Aim: Hence, present study aims to evaluate the pharmacognostic and analytical…
View article: Pharmaceutico-analytical Standardization of Katupila Taila; An Ayurvedic Dosage Form from Ethnobotany: Securinega leucopyrus
Pharmaceutico-analytical Standardization of Katupila Taila; An Ayurvedic Dosage Form from Ethnobotany: Securinega leucopyrus Open
Katupila - Securinega leucopyrus (willd) Muell. is ethnobotanic medicine, whose leaves are proven to exhibit wound healing property through in vitro, in vivo experimental studies and clinical study along with other properties like anti inf…
View article: Quality Control Assessment of an Ayurvedic Medicine - Durvadi Ghrita
Quality Control Assessment of an Ayurvedic Medicine - Durvadi Ghrita Open
Background: Durvadi Ghrita is a Sneha Kalpana which is claimed to be effective in Madhumehajanya Timira (Diabetic Retinopathy). In present study, it has been used for Nasya. Objective: Present study was planned to look out on herbal drugs …
View article: Aetiology, Evaluation and Management of Penile Fracture: Experience at a Teaching Hospital in Central India
Aetiology, Evaluation and Management of Penile Fracture: Experience at a Teaching Hospital in Central India Open
Introduction: Penile fracture is rupture of corpora cavernosa which occurs when the rigid penis is forcibly bent against resistance, leading to the disruption of tunica albuginea. There is classical history and physical examination before …
View article: Nitric oxide, lipid peroxidation products, and antioxidants in primary fibromyalgia and correlation with disease severity
Nitric oxide, lipid peroxidation products, and antioxidants in primary fibromyalgia and correlation with disease severity Open
Summary Background Fibromyalgia syndrome (FMS) is characterized by altered pain perception with chronic, widespread musculoskeletal pain. The relationship between nitric oxide, oxidative stress and the severity of FMS has not been studied.…
View article: Overexpression of the Cdk5 inhibitory peptide in motor neurons rescue of amyotrophic lateral sclerosis phenotype in a mouse model
Overexpression of the Cdk5 inhibitory peptide in motor neurons rescue of amyotrophic lateral sclerosis phenotype in a mouse model Open
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that affects motor nerve cells in the brain and the spinal cord. Etiological mechanisms underlying the disease remain poorly understood; recent studies suggest …
View article: Pharmacognostical and Phytochemical Evaluation of Leaf of Clerodendrum phlomidis Linn. F.
Pharmacognostical and Phytochemical Evaluation of Leaf of Clerodendrum phlomidis Linn. F. Open
Clerodendrum phlomidis Linn.f. is a large bush or small tree belonging to the family Verbenaceae. The present study deals with the pharmacognostical and phytochemical study of leaf including chromatographic evaluation. Clerodendrum phlomid…
View article: Comparative Phyto-pharmacognostical profile of stem of Ixora coccinea Linn. and Ixora arborea Roxb
Comparative Phyto-pharmacognostical profile of stem of Ixora coccinea Linn. and Ixora arborea Roxb Open
Ayurveda dating back to 1500-800 BC has been an integral part of Indian culture. The term comes from the Sanskrit root Ayu (life) and Veda (knowledge). Ixora is said to be native to Asia and whose name derives from an Indian deity. Till da…
View article: TFP5, a Peptide Inhibitor of Aberrant and Hyperactive Cdk5/p25, Attenuates Pathological Phenotypes and Restores Synaptic Function in CK-p25Tg Mice
TFP5, a Peptide Inhibitor of Aberrant and Hyperactive Cdk5/p25, Attenuates Pathological Phenotypes and Restores Synaptic Function in CK-p25Tg Mice Open
It has been reported that cyclin-dependent kinase 5 (cdk5), a critical neuronal kinase, is hyperactivated in Alzheimer’s disease (AD) and may be, in part, responsible for the hallmark pathology of amyloid plaques and neurofibrillary tangle…
View article: Knockdown of Expression of Cdk5 or p35 (a Cdk5 Activator) Results in Podocyte Apoptosis
Knockdown of Expression of Cdk5 or p35 (a Cdk5 Activator) Results in Podocyte Apoptosis Open
Podocytes are terminally differentiated glomerular epithelial cells. Podocyte loss has been found in many renal diseases. Cdk5 is a cyclin-dependent protein kinase which is predominantly regulated by p35. To study the role of Cdk5/p35 in p…
View article: Broad Spectrum Anti-Quorum Sensing Activity of Tannin-Rich Crude Extracts of Indian Medicinal Plants
Broad Spectrum Anti-Quorum Sensing Activity of Tannin-Rich Crude Extracts of Indian Medicinal Plants Open
Quorum sensing (QS) mechanisms have been demonstrated to have significance in expression of pathogenicity in infectious bacteria. In Gram negative bacteria the autoinducer molecules that mediate QS are acyl homoserine lactones (AHL) and in…
View article: Analysis of the Inhibitory Elements in the p5 Peptide Fragment of the CDK5 Activator, p35, CDKR1 Protein
Analysis of the Inhibitory Elements in the p5 Peptide Fragment of the CDK5 Activator, p35, CDKR1 Protein Open
Besides the hallmark pathology of amyloid plaques and neurofibrillary tangles, it is well documented that cyclin-dependent kinase 5 (CDK5), a critical neuronal protein kinase in nervous system development, function, and survival, when dere…