Varun Garg
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View article: A comparative analysis of vacuum assisted closure therapy and conventional dressings: outcomes in chronic diabetic foot ulcers among Indian patients
A comparative analysis of vacuum assisted closure therapy and conventional dressings: outcomes in chronic diabetic foot ulcers among Indian patients Open
Background: India faces a growing diabetes epidemic, with approximately 77 million individuals affected. Chronic non-healing diabetic foot ulcers (DFUs) are a common complication of diabetes and a major healthcare challenge in Conventional…
View article: Unraveling the role of chitosan for nasal drug delivery systems: A review
Unraveling the role of chitosan for nasal drug delivery systems: A review Open
The discipline of nanoscience has made enormous strides in the recent two decades. The researchers in the field of nanomedicine have been looking into using natural biodegradable polymeric nano-colloids for targeted drug delivery, due to t…
View article: Abstract 122
Abstract 122 Open
Background and Aims: Therapies that address multiple risk factors may help patients with type 2 diabetes (T2D) to improve their cardiometabolic risk profile. This exploratory analysis aimed to evaluate the efficacy of oral semaglutide in i…
View article: Enhancing Scalability and Reliability of Batch Data Transformation Workflows Using Automation and Orchestration Tools
Enhancing Scalability and Reliability of Batch Data Transformation Workflows Using Automation and Orchestration Tools Open
Moving data around in large volumes within big businesses is a natural happening of business nowadays. With this exponential growth, the need for more reliable, scalable, and effective batch data transformation techniques becomes increasin…
View article: FORMULATION, SYSTEMATIC OPTIMIZATION, IN VITRO, EX VIVO, AND STABILITY ASSESSMENT OF TRANSETHOSOME BASED GEL OF CURCUMIN
FORMULATION, SYSTEMATIC OPTIMIZATION, IN VITRO, EX VIVO, AND STABILITY ASSESSMENT OF TRANSETHOSOME BASED GEL OF CURCUMIN Open
Objectives: The current work presents a formulation of curcumin-loaded transethosome (CRM-TE) in the form of a gel and its characterization.Methods: Thirteen formulations were prepared by varying the concentration of Phospholipon 90G as li…
View article: INVESTIGATION AND OPTIMIZATION OF FORMULATION PARAMETERS FOR SELFNANOEMULSIFYING DELIVERY SYSTEM OF TWO LIPOPHILIC AND GASTROINTESTINAL LABILE DRUGS USING BOX-BEHNKEN DESIGN
INVESTIGATION AND OPTIMIZATION OF FORMULATION PARAMETERS FOR SELFNANOEMULSIFYING DELIVERY SYSTEM OF TWO LIPOPHILIC AND GASTROINTESTINAL LABILE DRUGS USING BOX-BEHNKEN DESIGN Open
Objective: Present research work aims toward codelivery of two hydrophobic drugs, curcumin (CRM) and duloxetine hydrochloride (DXH) through self-nanoemulsifying drug delivery systems (SNEDDS).Methods: Initially, binary mixture in the ratio…
View article: INFLUENCE OF FORMULATION PARAMETERS ON DISSOLUTION RATE ENHANCEMENT OF ACYCLOVIR USING LIQUISOLID FORMULATION
INFLUENCE OF FORMULATION PARAMETERS ON DISSOLUTION RATE ENHANCEMENT OF ACYCLOVIR USING LIQUISOLID FORMULATION Open
Objective: The objective of this research work is to explore the use of liquisolid technique in enhancement of acyclovir dissolution rate. This current study was planned to assess the impact of different formulation variables, such as non-…
View article: DESIGN AND PERFORMANCE VERIFICATION OF NEWLY DEVELOPED DISPOSABLE STATIC DIFFUSION CELL FOR DRUG DIFFUSION/PERMEABILITY STUDIES
DESIGN AND PERFORMANCE VERIFICATION OF NEWLY DEVELOPED DISPOSABLE STATIC DIFFUSION CELL FOR DRUG DIFFUSION/PERMEABILITY STUDIES Open
Objectives: The present study describes a disposable static diffusion cell for in vitro diffusion studies to achieve better results as compared to well existing Franz diffusion cell (FDC) in terms of the absence of bubbles, variable recept…
View article: FORMULATION OF CURCUMIN NANOSUSPENSION USING BOX-BEHNKEN DESIGN AND STUDY OF IMPACT OF DRYING TECHNIQUES ON ITS POWDER CHARACTERISTICS
FORMULATION OF CURCUMIN NANOSUSPENSION USING BOX-BEHNKEN DESIGN AND STUDY OF IMPACT OF DRYING TECHNIQUES ON ITS POWDER CHARACTERISTICS Open
Objective: The objective of this study was to formulate curcumin nanosuspension (NS) using Box-Behnken design (BBD) and solvent-antisolvent technique to overcome the challenges related to its poor dissolution rate.Methods: Sodium lauryl su…
View article: Novel biorelevant dissolution medium as a prognostic tool for polysaccharide-based colon-targeted drug delivery system
Novel biorelevant dissolution medium as a prognostic tool for polysaccharide-based colon-targeted drug delivery system Open
To overcome the limitations of the conventionally used methods for evaluation of orally administered colon-targeted delivery systems, a novel dissolution method using probiotics has been recently reported. In the present study, universal s…
View article: Evaluation of Intracranial Ring Lesions by Diffusion-Weighted Imaging and in Vivo Proton Magnetic Resonance Spectroscopy
Evaluation of Intracranial Ring Lesions by Diffusion-Weighted Imaging and in Vivo Proton Magnetic Resonance Spectroscopy Open
AIMS & OBJECTIVES:To assess the combined role of diffusion weighted imaging and spectroscopy in differentiating ring enhancing intracranial cystic lesions. MATERIALS AND METHIODS:The study was conducted from Oct 2011 to Sep 2013.Thirty (30…
View article: TERMINALIA CHEBULA: SUCCESS FROM BOTANY TO ALLOPATHIC AND AYURVEDIC PHARMACY
TERMINALIA CHEBULA: SUCCESS FROM BOTANY TO ALLOPATHIC AND AYURVEDIC PHARMACY Open
Terminalia chebula (TC) is a unique herb having various therapeutic potentials as anti-inflammatory, antioxidant, anticancer, and digestant. It belongsto family Combretaceae. In the present review, an attempt has been made to decipher clas…
View article: Open-Label Study to Evaluate the Safety & Tolerability of Telaprevir in Combination With Sofosbuvir in Naive Subjects Infected With Hepatitis C Virus Genotype 1
Open-Label Study to Evaluate the Safety & Tolerability of Telaprevir in Combination With Sofosbuvir in Naive Subjects Infected With Hepatitis C Virus Genotype 1 Open
Background & Aims : Sofosbuvir is a potent hepatitis C NS5B polymerase inhibitor that has led to high-sustained viral response rates when combined with other direct-acting antivirals. To date, no data exists on the combination of sofosbuvi…