Explanipedia

Trends in Infective Endocarditis Mortality in the United States: 1999 to 2020: A Cause for Alarm Open

Muchi Ditah Chobufo, Varunsiri Atti, Archana Vasudevan, Ruchi Bhandari, Vinay Badhwar , et al. · 2023

Background Data on national trends in mortality due to infective endocarditis (IE) in the United States are limited. Methods and Results Utilizing the multiple causes of death data from the Centers for Disease Control and Prevention's Wide…

Variation in Survival After Cardiopulmonary Arrest in Cardiac Catheterization Laboratories in the United States Open

Avnish Tripathi, Paul S. Chan, Mazen Albaghdadi, Mohammad Saud Khan, Varunsiri Atti , et al. · 2022

Even in controlled settings such as the CCL, there is significant hospital-level variation in survival after in-hospital cardiac arrest, which suggests an important opportunity to improve resuscitation outcomes in procedural areas.

A-48 | Heparin versus Bivalirudin Among Patients Undergoing Percutaneous Coronary Intervention (PCI): An Updated Meta-analysis Open

Pradeep Kumar Devarakonda, Sai Harika Pujari, Marie Liu, Nicholas Nourieh, Monika Karki , et al. · 2022

BackgroundAnticoagulant and antiplatelet therapy remain indispensable in the management of acute coronary syndrome; however, are associated with an increased risk of bleeding. This meta-analysis evaluates the efficacy and safety of bivalir…

Longitudinal Follow-Up of Asymptomatic COVID-19 Myocarditis with Cardiac Magnetic Resonance Imaging Open

Matthew K. Shotwell, Bandar A. Alyami, Kesavan Sankaramangalam, Varunsiri Atti, Yasmin S. Hamirani · 2022

BACKGROUND Varying degrees of cardiovascular involvement have been noted with COVID-19, with myocarditis being one of the feared complications. We present the case of a healthy, young individual with persistent myocardial involvement on ca…

A Comprehensive Review of Mechanical Circulatory Support Devices Open

Varunsiri Atti, Mahesh Anantha Narayanan, Brijesh Patel, Sudarshan Balla, Aleem Siddique , et al. · 2022

Treatment strategies to combat cardiogenic shock (CS) have remained stagnant over the past decade. Mortality rates among patients who suffer CS after acute myocardial infarction (AMI) remain high at 50%. Mechanical circulatory support (MCS…

Differential Effects of Cardiac Rehabilitation in Obese and Non-Obese Population Open

Varunsiri Atti, Pradeep Kumar Devarakonda, Sameer Raina · 2021

Background Cardiac rehabilitation (CR) improves outcomes in patients with heart disease. We investigated the differences in outcomes of comprehensive phase II CR in obese and non-obese patients. Methods We performed a retrospective analysi…

Transradial vs. Transfemoral Access for Percutaneous Coronary Intervention in STEMI: Meta-Analysis of Randomized Controlled Trials Open

Aravdeep Jhand, Varunsiri Atti, Rahul Dhwan, Mohit K. Turagam, Natraj Kataa , et al. · 2020

Multivessel Versus Culprit-Only Revascularization in STEMI and Multivessel Coronary Artery Disease Open

Varunsiri Atti, Yeongjin Gwon, Mahesh Anantha Narayanan, Santiago García, Yader Sandoval , et al. · 2020

An Update on the Reversal of Non-Vitamin K Antagonist Oral Anticoagulants Open

Mark Mujer, P Manoj, Varunsiri Atti, Ian Dimaandal, Abigail Chan , et al. · 2020

Non-vitamin K antagonist oral anticoagulants (NOACs) include thrombin inhibitor dabigatran and coagulation factor Xa inhibitors rivaroxaban, apixaban, edoxaban, and betrixaban. NOACs have several benefits over warfarin, including faster ti…

Issue Information ‐ TOC Open

David E. Kandzari, Dimitri Karmpaliotis, Annapoorna Kini, Jeffrey W. Moses, Pradyumna E. Tummala , et al. · 2019

Outcomes and Resource Utilization Associated With Readmissions After Atrial Fibrillation Hospitalizations Open

Byomesh Tripathi, Varunsiri Atti, Varun Kumar, Vamsidhar Naraparaju, Purnima Sharma , et al. · 2019

Background Atrial fibrillation is the most common arrhythmia worldwide. Data regarding 30‐day readmission rates after discharge for atrial fibrillation remain poorly reported. Methods and Results The Nationwide Readmission Database (2010–2…

Transcatheter aortic valve replacement in Bicuspid Aortic Valve Disease: An Insight Open

Varshil Mehta, Nikhil Nalluri, Varun Kumar, Nileshkumar Patel, Varunsiri Atti , et al. · 2019

As per the current scenario, role of Transcatheter aortic valve replacement (TAVI) is controversial in bicuspid aortic valve stenosis. All the randomized clinical trials comparing outcomes of TAVI with surgery till date, have excluded pati…

Burden and trends of arrhythmias in hypertrophic cardiomyopathy and its impact of mortality and resource utilization Open

Byomesh Tripathi, Safi U. Khan, Shilpkumar Arora, Varun Kumar, Vamsidhar Naraparaju , et al. · 2019

Background Hypertrophic cardiomyopathy (HCM) accounts for significant morbidity and mortality worldwide. Arrhythmias are considered the main cause of mortality, however, there is paucity of data relating to trends of arrhythmia and associa…

Contents Open

Christopher M. Cannon, Robert J. Sanchez, Alexa C. Klimchak, Irfan Khan, William J. Sasiela , et al. · 2019

Anticoagulation After Catheter Ablation of Atrial Fibrillation: Is it time to Discontinue in Select Patient Population? Open

Varunsiri Atti · 2018

In conclusion, discontinuation of oral anticoagulation 3 months after a successful AF ablation appears to be safe in highly selected closely monitored patients. Further randomized trials are warranted to assess the safety of discontinuing …

Surgical left atrial appendage occlusion during cardiac surgery: A systematic review and meta-analysis Open

Varunsiri Atti, Mahesh Anantha Narayanan, Mohit K. Turagam, Scott Koerber, Sunil V. Rao , et al. · 2018

Concomitant s-LAAO during cardiac surgery was associated with lower risk of follow-up thromboembolic events and stroke, especially in those with AF without significant increase in adverse events. Further randomized trials to evaluate long-…

Drug-Eluting Stents Versus Bare-Metal Stents in Saphenous Vein Graft Intervention Open

Nileshkumar Patel, Chirag Bavishi, Varunsiri Atti, Avnish Tripathi, Nikhil Nalluri , et al. · 2018

Background Percutaneous coronary intervention with drug-eluting stents (DES) has been increasingly used for revascularization of saphenous vein graft stenosis without strong clinical evidence favoring their use. Randomized controlled trial…

Spontaneous rupture of a pancreatic pseudocyst Open

Mark Mujer, P Manoj, Varunsiri Atti, Shiva Shrotriya · 2018

This is a case of a 50-year-old woman with medical history significant for chronic pancreatitis secondary to alcohol abuse who initially presented with a 3-week history of progressively worsening epigastric pain. The patient described the …

Sarcomatoid carcinoma of the duodenum Open

Julie Yam, P Manoj, Divyesh Nemakayala, Varunsiri Atti · 2018

A 69-year-old Caucasian man presented to the gastroenterology clinic with complaints of nausea, abdominal pain and more than 100-pound unintentional weight loss over the past 1 year. He had a history of colon polyps and was overdue for sur…

Coxsackie Myocarditis and Hepatitis with Reactivated Epstein-Bar Virus (EBV): A Case Report Open

Varunsiri Atti, Nathan Anderson, Mathew B. Day · 2017

BACKGROUND Myocarditis, defined as inflammation of myocardial tissue of the heart, is an uncommon cardiac presentation and is due to a variety of causes. It affects 1% of the US population, 50% of which is caused by coxsackie B virus. Card…

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