Vasilisa Skvortsova
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View article: Neural variability in the medial prefrontal cortex contributes to efficient adaptive behavior
Neural variability in the medial prefrontal cortex contributes to efficient adaptive behavior Open
Neural variability, i.e. random fluctuations in neural activity, is a ubiquitous and sizable brain feature that impacts behavior. Its functional role however remains unclear and neural variability is commonly viewed as a nuisance factor de…
View article: From promise to practice: towards the realisation of AI-informed mental health care
From promise to practice: towards the realisation of AI-informed mental health care Open
In this Series paper, we explore the promises and challenges of artificial intelligence (AI)-based precision medicine tools in mental health care from clinical, ethical, and regulatory perspectives. The real-world implementation of these t…
View article: The promise of a model-based psychiatry: building computational models of mental ill health
The promise of a model-based psychiatry: building computational models of mental ill health Open
Computational models have great potential to revolutionise psychiatry research and clinical practice. These models are now used across multiple subfields, including computational psychiatry and precision psychiatry. Their goals vary from u…
View article: Distinct computational mechanisms underlying cognitive flexibility deficits in impulsivity and compulsivity
Distinct computational mechanisms underlying cognitive flexibility deficits in impulsivity and compulsivity Open
Cognitive flexibility, the ability to quickly adapt to changing environmental demands, is a hallmark of human behaviour, and is impaired across multiple psychiatric disorders. Especially compulsivity and impulsivity disorders have been lin…
View article: Obsessive–compulsive symptoms and information seeking during the Covid-19 pandemic
Obsessive–compulsive symptoms and information seeking during the Covid-19 pandemic Open
Increased mental-health symptoms as a reaction to stressful life events, such as the Covid-19 pandemic, are common. Critically, successful adaptation helps to reduce such symptoms to baseline, preventing long-term psychiatric disorders. It…
View article: A Causal Role for the Pedunculopontine Nucleus in Human Instrumental Learning
A Causal Role for the Pedunculopontine Nucleus in Human Instrumental Learning Open
View article: A Selective Increase in OC Symptoms is Driving Information Seeking and Guideline Adherence During the Covid-19 Pandemic
A Selective Increase in OC Symptoms is Driving Information Seeking and Guideline Adherence During the Covid-19 Pandemic Open
Background Increased mental health problems as a reaction to stressful life events, such as the Covid-19 pandemic, are common. Critically, successful adaptation helps reduce such symptoms to baseline, preventing long-term psychiatric disor…
View article: Cerebellar anaplastic astrocytoma in adult patients: 15 consecutive cases from a single institution and literature review
Cerebellar anaplastic astrocytoma in adult patients: 15 consecutive cases from a single institution and literature review Open
Adult cerebellar anaplastic astrocytomas (cAA) are rare entities and their clinical and genetic appearances are still ill defined. Previously, malignant gliomas of the cerebellum were combined and reviewed together (cAA and cerebellar glio…
View article: Computational noise in reward-guided learning drives behavioral variability in volatile environments
Computational noise in reward-guided learning drives behavioral variability in volatile environments Open
When learning the value of actions in volatile environments, humans often make seemingly irrational decisions which fail to maximize expected value. We reasoned that these ‘non-greedy’ decisions, instead of reflecting information seeking d…
View article: How context alters value: The brain’s valuation and affective regulation system link price cues to experienced taste pleasantness
How context alters value: The brain’s valuation and affective regulation system link price cues to experienced taste pleasantness Open
View article: A Selective Role for Dopamine in Learning to Maximize Reward But Not to Minimize Effort: Evidence from Patients with Parkinson's Disease
A Selective Role for Dopamine in Learning to Maximize Reward But Not to Minimize Effort: Evidence from Patients with Parkinson's Disease Open
Instrumental learning is a fundamental process through which agents optimize their choices, taking into account various dimensions of available options such as the possible reward or punishment outcomes and the costs associated with potent…
View article: How context alters value: Price information recruits the brain’s valuation and affective regulation system for shaping experienced taste pleasantness
How context alters value: Price information recruits the brain’s valuation and affective regulation system for shaping experienced taste pleasantness Open
SUMMARY Informational cues such as the price of a wine can trigger expectations about its taste quality and thereby modulate the sensory experience on a reported and neural level. Yet it is unclear how the brain translates such expectation…