Vasudha Devi
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View article: Role of human Myocyte Enhancer Factor 2 (MEF2) proteins in cancer: structural insights, functional diversity, and regulatory mechanisms
Role of human Myocyte Enhancer Factor 2 (MEF2) proteins in cancer: structural insights, functional diversity, and regulatory mechanisms Open
The Myocyte Enhancer Factor 2 (MEF2) family of transcription factors plays a central role in regulating key cellular processes, including differentiation, proliferation, apoptosis and stress response. MEF2 activity is important for normal …
View article: Efficacy of Subjective and Objective Nutritional Assessment in Children: A Cross-sectional Study
Efficacy of Subjective and Objective Nutritional Assessment in Children: A Cross-sectional Study Open
Introduction: Globally, malnutrition represents a critical health concern, particularly among children. Research has consistently shown that undernutrition is highly prevalent in children admitted to hospitals, with reported rates ranging …
View article: Phytochemical and pharmacoinformatics analysis of a traditional antipsoriatic oil formulation for its potential against proinflammatory cytokines TNF-α and IL-17A
Phytochemical and pharmacoinformatics analysis of a traditional antipsoriatic oil formulation for its potential against proinflammatory cytokines TNF-α and IL-17A Open
Psoriasis, a persistent inflammatory condition with a complex origin, lacks a definitive cure despite the availability of diverse treatments. Vetpalai thailam (VT), a Siddha formulation, is commonly used for addressing various skin ailment…
View article: Machine-learning-based artificial intelligence tools for the diagnosis of tropical fevers: a systematic review and meta-analysis protocol of diagnostic test accuracy
Machine-learning-based artificial intelligence tools for the diagnosis of tropical fevers: a systematic review and meta-analysis protocol of diagnostic test accuracy Open
Introduction Recent advancements in diagnosing tropical fevers increasingly use artificial intelligence (AI). These innovations focus on diagnosing single or multiple diseases, significantly reducing the global burden of tropical fevers. T…
View article: Perceived learning gaps in paediatric anaesthesia training: A cross-sectional survey
Perceived learning gaps in paediatric anaesthesia training: A cross-sectional survey Open
Background and Aims: Paediatric anaesthesia requires specialised skills to manage patients effectively, yet training often falls short of clinical needs. To address this, a survey was conducted among anaesthesia trainees and teachers to id…
View article: Prevalent Plant Growth Hormone Indole-3-acetic Acid Produced by Streptomyces sp. VSMKU1027 and its Potential Antifungal Activity against Phytofungal Pathogens
Prevalent Plant Growth Hormone Indole-3-acetic Acid Produced by Streptomyces sp. VSMKU1027 and its Potential Antifungal Activity against Phytofungal Pathogens Open
Microorganisms and plants can produce indole-3-acetic acid (IAA) by mechanisms that either involve tryptophan or do not involve tryptophan. The control of Zone of inhibition (ZOI) ranged from 1.2 cm to 1.0 cm. A promising antagonistic isol…
View article: Cell and molecular targeted therapies for diabetic retinopathy
Cell and molecular targeted therapies for diabetic retinopathy Open
Diabetic retinopathy (DR) stands as a prevalent complication in the eye resulting from diabetes mellitus, predominantly associated with high blood sugar levels and hypertension as individuals age. DR is a severe microvascular complication …
View article: Cell-specific extracellular vesicle-encapsulated exogenous GABA controls seizures in epilepsy
Cell-specific extracellular vesicle-encapsulated exogenous GABA controls seizures in epilepsy Open
Background Epilepsy affects ∼60 million people worldwide. Most antiseizure medications in the market act on voltage-gated sodium or calcium channels, indirectly modulating neurotransmitter GABA or glutamate levels or multiple targets. Earl…
View article: Small extracellular vesicle-loaded bevacizumab reduces the frequency of intravitreal injection required for diabetic retinopathy
Small extracellular vesicle-loaded bevacizumab reduces the frequency of intravitreal injection required for diabetic retinopathy Open
Diabetic retinopathy (DR) is associated with retinal neovascularization, hard exudates, inflammation, oxidative stress and cell death, leading to vision loss. Anti-vascular endothelial growth factor (Anti-VEGF) therapy through repeated int…
View article: Development and validation of Manipal Inventory for Curriculum Evaluation (MICE): A comprehensive tool for evaluation of hybrid medical curriculum
Development and validation of Manipal Inventory for Curriculum Evaluation (MICE): A comprehensive tool for evaluation of hybrid medical curriculum Open
Background: In outcome-based education, the components of the curriculum must facilitate the students to attain expected outcomes. Hence, it is imperative to evaluate the components of the curriculum. Objective: The study aimed to develop …
View article: Establishing links between assessments and expected learning outcomes through curriculum mapping in a dental physiology curriculum
Establishing links between assessments and expected learning outcomes through curriculum mapping in a dental physiology curriculum Open
. Through curriculum mapping, we were able to establish links between assessments and expected learning outcomes. We observed that, in the assessment system followed at MMMC, all expected learning outcomes were not given equal weightage in…
View article: Evaluation of a mentored student project programme using reflective summaries
Evaluation of a mentored student project programme using reflective summaries Open
. Reflective summaries as a means to evaluate the MSP programme was found to be an easy, feasible and cost-effective method. The qualitative approach adopted for data analysis enabled the programme coordinators to assess the strengths and …
View article: Using an integrated teaching approach to facilitate student achievement of the learning outcomes in a preclinical medical curriculum in India
Using an integrated teaching approach to facilitate student achievement of the learning outcomes in a preclinical medical curriculum in India Open
Today most education institutions around the world have adopted the philosophy of outcome-based education. The emphasis in outcome-based education is achievement of outcomes; hence the curriculum should be designed in a way that it include…
View article: AWARENESS OF FIRST YEAR MBBS STUDENTS ON MBBS DEGREE AND THEIR IDEAS: AN UNEXPECTED REALITY
AWARENESS OF FIRST YEAR MBBS STUDENTS ON MBBS DEGREE AND THEIR IDEAS: AN UNEXPECTED REALITY Open
Introduction: MBBS is a dream to cherish for all students.It is a course which is respected globally.Medical course is perceived as stressful by many of the undergraduates all over the world.They join the course at an early age without awa…
View article: VERNONIA CINEREA (NEICHITTI KEERAI) REGENERATES PROXIMAL TUBULES IN CISPLATININDUCED RENAL DAMAGE IN MICE
VERNONIA CINEREA (NEICHITTI KEERAI) REGENERATES PROXIMAL TUBULES IN CISPLATININDUCED RENAL DAMAGE IN MICE Open
Objective: The aim of the study was to evaluate whether Vernonia cinerea (VC) regenerates the proximal renal tubular cells in cisplatin-induced necrosis in male Swiss albino mice.Methods: The crude aqueous extract (CAE) of VC was fractiona…
View article: VERNONIA CINEREA (NEICHITTI KEERAI) REGENERATES PROXIMAL TUBULES IN CISPLATININDUCED RENAL DAMAGE IN MICE
VERNONIA CINEREA (NEICHITTI KEERAI) REGENERATES PROXIMAL TUBULES IN CISPLATININDUCED RENAL DAMAGE IN MICE Open
Objective: The aim of the study was to evaluate whether Vernonia cinerea (VC) regenerates the proximal renal tubular cells in cisplatin-induced necrosis in male Swiss albino mice.Methods: The crude aqueous extract (CAE) of VC was fractiona…
View article: Cytoprotective Activity of Neichitti (Vernonia cinerea) in Human Embryonic Kidney (HEK293) Normal Cells and Human Cervix Epitheloid Carcinoma (HeLa) Cells against Cisplatin Induced Toxicity: A Comparative Study
Cytoprotective Activity of Neichitti (Vernonia cinerea) in Human Embryonic Kidney (HEK293) Normal Cells and Human Cervix Epitheloid Carcinoma (HeLa) Cells against Cisplatin Induced Toxicity: A Comparative Study Open
Introduction: Traditional Siddha Medicine literatures suggest to use the decoction of Vernonia cinerea (VC) to alleviate toxic effects caused by metals. Cisplatin, a metal used in cancer treatment is known to cause nephrotoxicity. Aim: To …
View article: INFLUENCE OF GENDER AND OBESITY ON ANALGESIC MODULATION OF TRAMADOL IN RATS
INFLUENCE OF GENDER AND OBESITY ON ANALGESIC MODULATION OF TRAMADOL IN RATS Open
Objective: The objective of this study was to investigate the influence of gender and obesity on analgesic modulation of tramadol in Wistar rats.Methods: This study was carried out in two sets of experiments. In Set I experiment - 48 rats …
View article: Assessment for learning: a needs analysis study using formative assessment to evaluate the need for curriculum reform in basic sciences
Assessment for learning: a needs analysis study using formative assessment to evaluate the need for curriculum reform in basic sciences Open
A needs analysis study for curriculum reform in basic sciences was conducted at Melaka Manipal Medical College, India, by means of a formative assessment method, namely Basic Science Retention Examination (BSRE). Students participated in a…
View article: CORRELATION OF GENDER AND LEPTIN WITH ANALGESIC EFFECT OF TRAMADOL IN RATS
CORRELATION OF GENDER AND LEPTIN WITH ANALGESIC EFFECT OF TRAMADOL IN RATS Open
Objective: The objective of the study was to investigate the correlation of gender and serum leptin level with analgesic modulation of tramadol in Wistar rats.Methods: A total of 48 Wistar rats (body weight 100–150 g), 24 each male and fem…
View article: Correlation of Gender and Leptin with Analgesic Effect of Tramadol in High Fat Diet Induced Obese Rats
Correlation of Gender and Leptin with Analgesic Effect of Tramadol in High Fat Diet Induced Obese Rats Open
Introduction: Gender and obesity related influences on the experience of pain have received considerable empirical attention in recent years. Differences in pain sensitivity among individuals may have implications for pain management which…
View article: Teaching and Assessing Reflecting Skills among Undergraduate Medical Students Experiencing Research
Teaching and Assessing Reflecting Skills among Undergraduate Medical Students Experiencing Research Open
Teaching and assessing reflecting skills among students using research experience as context was feasible. This study demonstrated that students acquire better reflecting skills after undergoing training.
View article: Curricular Impact on Learning Approaches and Critical Thinking Skills of Medical Students
Curricular Impact on Learning Approaches and Critical Thinking Skills of Medical Students Open
Objectives: This investigation focused on finding the changes in learning approaches of students' while experiencing physiology curriculum and to explore the reflection of changes if any, on their critical thinking skills.Methods: In this …
View article: Learning Habits of Undergraduate Medical Students in Pharmacology
Learning Habits of Undergraduate Medical Students in Pharmacology Open
International Journal of Pharmacology and Clinical Sciences,2015,4,3,63-67.DOI:10.5530/ijpcs.4.3.6Published:September 2015Type:Original ArticleAuthors:Vasudha Devi, Zulhashime bin Zulkifli, Abdul Hadi bin Abd Rahman, Nurul Wahida Amalin bi…
View article: Undergraduate pharmacology curriculum at an international medical college in India
Undergraduate pharmacology curriculum at an international medical college in India Open
Pharmacology is an important aspect of rational therapeutics. There has been a long-standing need for a change in the undergraduate medical curriculum of pharmacology. A review of literature throws up different approaches to improve the cu…
View article: Cost, Benefit and Risks Associated with in-Campus and off-Campus Accommodations of Medical Students: A cross-Sectional Study
Cost, Benefit and Risks Associated with in-Campus and off-Campus Accommodations of Medical Students: A cross-Sectional Study Open
International Journal of Pharmacology and Clinical Sciences,2015,4,3,58-62.DOI:10.5530/ijpcs.4.3.5Published:Sept 2015Type:Original ArticleAuthors:Vasudha Devi, Sabrina Najiha Binti Mohamad Ashari, Syahirah Binti Abd Rashid, Muhammad Azim B…
View article: Students’ And Teachers’ Characteristics Promoting Student’s Learning During Lecture Classes
Students’ And Teachers’ Characteristics Promoting Student’s Learning During Lecture Classes Open
Introduction:In spite of general call for a reduction in the number of lecture classes scheduled in a curriculum, the lecture remains one of the most widely used instructional methods in medical schools.Hence, lecture classes must be fine-…