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View article: Lipoprotein metabolism and inflammation in healthy young subjects – exploring the postprandial and postabsorptive phases following intake of a standardized meal
Lipoprotein metabolism and inflammation in healthy young subjects – exploring the postprandial and postabsorptive phases following intake of a standardized meal Open
Background and aims Non-fasting blood sampling is increasingly recommended for routine lipid testing in cardiovascular disease risk assessment. However, these recommendations are mainly based on associations between lipid levels and self-r…
View article: Serum concentrations of lipids, ketones and acylcarnitines during the postprandial and fasting state: the Postprandial Metabolism (PoMet) study in healthy young adults
Serum concentrations of lipids, ketones and acylcarnitines during the postprandial and fasting state: the Postprandial Metabolism (PoMet) study in healthy young adults Open
To improve the interpretation and utilisation of blood lipids, ketones and acylcarnitine concentrations as biomarkers in clinical assessments, more information is needed on their dynamic alterations in response to dietary intake and fastin…
View article: Association between dietary macronutrient composition and plasma one-carbon metabolites and B-vitamin cofactors in patients with stable angina pectoris
Association between dietary macronutrient composition and plasma one-carbon metabolites and B-vitamin cofactors in patients with stable angina pectoris Open
Elevated plasma concentrations of several one-carbon metabolites are associated with increased CVD risk. Both diet-induced regulation and dietary content of one-carbon metabolites can influence circulating concentrations of these markers. …
View article: Preparatory work for the update of the tolerable upper intake levels for vitamin A
Preparatory work for the update of the tolerable upper intake levels for vitamin A Open
This report describes collection of data and appraisal of scientific evidence in relation to assessment of Upper Levels (UL) for vitamin A. In the SR on teratogenicity, 370 records were identified and reduced to 23 records after screening …
View article: Riboflavin: a scoping review for Nordic Nutrition Recommendations 2023
Riboflavin: a scoping review for Nordic Nutrition Recommendations 2023 Open
Only a few studies have explored relationships between riboflavin intake and function and a few studies have examined the effects of supplements on various clinical or biochemical outcomes. None of these studies, however, make a useful con…
View article: Niacin – a scoping review for Nordic Nutrition Recommendations 2023
Niacin – a scoping review for Nordic Nutrition Recommendations 2023 Open
Niacin is the precursor to pyridine nucleotides NAD (nicotinamide adenine dinucleotide) and NADP (nicotinamide adenine dinucleotide phosphate). Niacin (vitamin B3) is the common term for nicotinic acid, nicotinamide and derivatives that ex…
View article: Vitamin B12 – a scoping review for Nordic Nutrition Recommendations 2023
Vitamin B12 – a scoping review for Nordic Nutrition Recommendations 2023 Open
Vitamin B12 (cobalamin) is essential for normal metabolic function, and even moderate deficiency of this vitamin has negative health effects. Vitamin B12 is found in animal foods, and as vegetarian diets are increasingly popular in Western…
View article: Time-resolved concentrations of serum amino acids, one-carbon metabolites and B-vitamin biomarkers during the postprandial and fasting state: the Postprandial Metabolism in Healthy Young Adults (PoMet) Study
Time-resolved concentrations of serum amino acids, one-carbon metabolites and B-vitamin biomarkers during the postprandial and fasting state: the Postprandial Metabolism in Healthy Young Adults (PoMet) Study Open
Metabolomics has been utilised in epidemiological studies to investigate biomarkers of nutritional status and metabolism in relation to non-communicable diseases. However, little is known about the effect of prandial status on several biom…
View article: Cystatin C proteoforms in chronic kidney disease
Cystatin C proteoforms in chronic kidney disease Open
Cystatin C, a cysteine protease inhibitor, is used as a biomarker of renal function. It offers several advantages compared to creatinine, and formulas for the estimation of the glomerular filtration rate based on cystatin C have been devel…
View article: Plasma methylmalonic acid predicts risk of acute myocardial infarction and mortality in patients with coronary heart disease: A prospective 2‐cohort study
Plasma methylmalonic acid predicts risk of acute myocardial infarction and mortality in patients with coronary heart disease: A prospective 2‐cohort study Open
Background Elevated plasma methylmalonic acid (MMA) is reported in patients with established coronary heart disease (CHD) and is considered a marker of vitamin B12 deficiency. Moreover, MMA‐dependent reactions have been linked to alteratio…
View article: The association between dairy intake and risk of cardiovascular disease and mortality in patients with stable angina pectoris
The association between dairy intake and risk of cardiovascular disease and mortality in patients with stable angina pectoris Open
Aims The association of dairy products with cardiovascular disease and mortality risk remains heavily debated. We aimed to investigate the association between intake of total dairy and dairy products and the risk of acute myocardial infarc…
View article: Sixteen-week multicentre randomised controlled trial to study the effect of the consumption of an oat beta-glucan-enriched bread versus a whole-grain wheat bread on glycaemic control among persons with pre-diabetes: a study protocol of the CarbHealth study
Sixteen-week multicentre randomised controlled trial to study the effect of the consumption of an oat beta-glucan-enriched bread versus a whole-grain wheat bread on glycaemic control among persons with pre-diabetes: a study protocol of the CarbHealth study Open
Introduction In 2012, the estimated global prevalence of pre-diabetes was 280 million, and the prevalence is expected to rise to 400 million by 2030. Oat-based foods are a good source of beta-glucans, which have been shown to lower postpra…
View article: Food choices and life expectancy: is it just beans?
Food choices and life expectancy: is it just beans? Open
In response to: Fadnes LT, Økland J-M, Haaland ØA, Johansson KA. Estimating impact of food choices on life expectancy: A modeling study. PLoS Med 2022; 19: e1003889. https://doi.org/10.1371/journal.pmed.1003889
View article: Additional file 1 of MRI adipose tissue segmentation and quantification in R (RAdipoSeg)
Additional file 1 of MRI adipose tissue segmentation and quantification in R (RAdipoSeg) Open
Additional file 1: can be viewed in RStudio ( https://www.rstudio.com/ ) Complete code for performing adipose tissue segmentation with RAdiposeg. This format allows for convenient and direct use of the code in RStudio.
View article: Additional file 6 of MRI adipose tissue segmentation and quantification in R (RAdipoSeg)
Additional file 6 of MRI adipose tissue segmentation and quantification in R (RAdipoSeg) Open
Additional file 6. MRI image data. All data collected from each MRI image using the RAdipoSeg and SliceOmatic segmentation methods.
View article: Additional file 7 of MRI adipose tissue segmentation and quantification in R (RAdipoSeg)
Additional file 7 of MRI adipose tissue segmentation and quantification in R (RAdipoSeg) Open
Additional file 7. Readme file with details about Additional file 6.
View article: Assessment of Dietary Choline Intake, Contributing Food Items, and Associations with One-Carbon and Lipid Metabolites in Middle-Aged and Elderly Adults: The Hordaland Health Study
Assessment of Dietary Choline Intake, Contributing Food Items, and Associations with One-Carbon and Lipid Metabolites in Middle-Aged and Elderly Adults: The Hordaland Health Study Open
Phosphatidylcholine was the most consumed choline form in community-dwelling adults in Norway. Our findings suggest that choline intake is associated with the concentration of most metabolites involved in the one-carbon and lipid metabolis…
View article: Food Sources Contributing to Intake of Choline and Individual Choline Forms in a Norwegian Cohort of Patients With Stable Angina Pectoris
Food Sources Contributing to Intake of Choline and Individual Choline Forms in a Norwegian Cohort of Patients With Stable Angina Pectoris Open
Background: Choline is an essential nutrient involved in a wide range of physiological functions. It occurs in water- and lipid-soluble forms in the body and diet. Foods with a known high choline content are eggs, beef, chicken, milk, fish…
View article: The Association of Meat Intake With All-Cause Mortality and Acute Myocardial Infarction Is Age-Dependent in Patients With Stable Angina Pectoris
The Association of Meat Intake With All-Cause Mortality and Acute Myocardial Infarction Is Age-Dependent in Patients With Stable Angina Pectoris Open
Background: Red and processed meat intake have been associated with increased risk of morbidity and mortality, and a restricted intake is encouraged in patients with cardiovascular disease. However, evidence on the association between tota…
View article: β-blocker use and risk of all-cause mortality in patients with coronary heart disease: effect modification by serum vitamin A
β-blocker use and risk of all-cause mortality in patients with coronary heart disease: effect modification by serum vitamin A Open
Aims Blockade of β-adrenoceptors reduces sympathetic nervous system activity and improves survival in patients with heart failure with reduced left ventricular ejection fraction (HFrEF); however, any improvement in longevity among patients…
View article: Lipid parameters and vitamin A modify cardiovascular risk prediction by plasma neopterin
Lipid parameters and vitamin A modify cardiovascular risk prediction by plasma neopterin Open
Objectives Oxidised cholesterol metabolites are linked to increased production of the active vitamin A (Vit-A) form and monocyte/macrophage activation, which may be reflected by neopterin, a marker of both interferon-γ–mediated immune acti…
View article: Association of dietary vitamin K and risk of coronary heart disease in middle-age adults: the Hordaland Health Study Cohort
Association of dietary vitamin K and risk of coronary heart disease in middle-age adults: the Hordaland Health Study Cohort Open
Objective The role of vitamin K in the regulation of vascular calcification is established. However, the association of dietary vitamins K1 and K2 with risk of coronary heart disease (CHD) is inconclusive. Design Prospective cohort study. …
View article: Dietary composition is associated with one-carbon metabolites and B-vitamin status in patients with stable angina – a cross-sectional study
Dietary composition is associated with one-carbon metabolites and B-vitamin status in patients with stable angina – a cross-sectional study Open
Introduction: Peroxisome Proliferator-Activated Receptor α (PPARα) is a known regulator of lipid and energy metabolism. In animal experiments of PPARα activation, we have reported on altered plasma concentration of metabolites related to o…
View article: Short-term treatment with a peroxisome proliferator-activated receptor α agonist influences plasma one-carbon metabolites and B-vitamin status in rats
Short-term treatment with a peroxisome proliferator-activated receptor α agonist influences plasma one-carbon metabolites and B-vitamin status in rats Open
Treatment with a PPARα agonist influenced plasma concentration of one-carbon metabolites and markers of B-vitamin status. This confirms previous findings, suggesting specific involvement of PPARα in the regulation of these metabolic pathwa…
View article: Biomarkers of one-carbon metabolism and B-vitamin status : Targeted metabolomics in rats and humans exploring the effects of PPARα-activation and dietary composition
Biomarkers of one-carbon metabolism and B-vitamin status : Targeted metabolomics in rats and humans exploring the effects of PPARα-activation and dietary composition Open
BACKGROUND: One-carbon metabolism is an overarching term describing central metabolic pathways involved in the transfer of one-carbon units. These include the methionine-homocysteine and folate cycles, as well as the choline oxidation and …