Xinyi Wang
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View article: Design and Synthesis of a Bio‐Based <scp>DOPO</scp> ‐ <scp>ITA</scp> Flame‐Retardant Monomer for Modifying <scp> CO <sub>2</sub> </scp> ‐Based Polycarbonates
Design and Synthesis of a Bio‐Based <span>DOPO</span> ‐ <span>ITA</span> Flame‐Retardant Monomer for Modifying <span> CO <sub>2</sub> </span> ‐Based Polycarbonates Open
This study tackles the poor flame retardancy of CO 2 ‐based poly(propylene carbonate) (PPC) by synthesizing a known biobased phosphorus‐containing monomer, DOPO‐ITA, and for the first time, incorporating it as a flame‐retardant functional …
View article: Role of antifungal drugs in modulating interaction between <i>Candida glabrata</i> and macrophages: cytokine profiles and TEM analysis
Role of antifungal drugs in modulating interaction between <i>Candida glabrata</i> and macrophages: cytokine profiles and TEM analysis Open
Candida glabrata often resides within macrophages, creating challenges for antifungal treatment. This study investigates the impact of antifungal agents on the immune response of C. glabrata within macrophages to understand its immune evas…
View article: Effects of scale and form of verandas on thermal protection performance
Effects of scale and form of verandas on thermal protection performance Open
Veranda serves as a shading and heat protection area for homes in hot and humid regions, connecting indoor and outdoor spaces. However, there is limited literature on precise veranda design for climate regulation. This research focuses on …
View article: Comparison of triglyceride-glucose index and triglyceride-glucose related indexes in predicting cardiovascular disease incidence among populations with cardiovascular-kidney-metabolic syndrome stages 0-3: a nationwide prospective cohort study
Comparison of triglyceride-glucose index and triglyceride-glucose related indexes in predicting cardiovascular disease incidence among populations with cardiovascular-kidney-metabolic syndrome stages 0-3: a nationwide prospective cohort study Open
Background The association of the triglyceride glucose (TyG) index and related TyG metrics with obesity indices has been demonstrated to correlate with the incidence of cardiovascular disease (CVD). Nonetheless, this relationship has not b…
View article: The critical role of matrix metalloproteinase 9-mediated microglial polarization in perioperative neurocognitive disorders of aged rats
The critical role of matrix metalloproteinase 9-mediated microglial polarization in perioperative neurocognitive disorders of aged rats Open
Background Perioperative neurocognitive disorders (PND) is a significant clinical syndrome and neuroinflammation is an important pathological process. Matrix metalloproteinase 9 (MMP9) as a Zn2+-dependent matrix enzyme, not only maintains …
View article: Cost-utility of endoscopic screening strategies for upper gastrointestinal cancer across China: a modeling study
Cost-utility of endoscopic screening strategies for upper gastrointestinal cancer across China: a modeling study Open
Introduction Endoscopic screening for upper gastrointestinal cancer (UGC) is effective, but it's cost-utility across comprehensive strategies remains unclear. We aimed to assess the cost-utility of various endoscopic screening strategies f…
View article: OPTIMIZATION PATH FOR GIRE STATION LAYOUT BASED ON PAGERANK
OPTIMIZATION PATH FOR GIRE STATION LAYOUT BASED ON PAGERANK Open
This article focuses on the optimization of fire station layout, aiming to explore a more scientific and reasonable layout path by introducing the PageRank algorithm. Firstly, the importance of optimizing the layout of fire stations and th…
View article: Age-period-cohort analysis of syphilis epidemics in Eastern China, China, 2005–2024
Age-period-cohort analysis of syphilis epidemics in Eastern China, China, 2005–2024 Open
Background Syphilis remains one of the serious public health challenges in China and worldwide. This study aims to assess the potential independent risks associated with age, period, and birth cohort for the reported incidence of syphilis …
View article: Overexpression of colonic VIP ameliorates cognitive function and barrier system damage caused by sevoflurane anesthesia and surgery in aged rats with fragile brain functions
Overexpression of colonic VIP ameliorates cognitive function and barrier system damage caused by sevoflurane anesthesia and surgery in aged rats with fragile brain functions Open
These findings indicate that VIP upregulation mitigates anesthesia- and surgery-induced cognitive impairment and its progression in aged rats with fragile brain function a, primarily by modulating the inflammatory response and preserving t…
View article: Real-time dynamic monitoring and multiplex PCR identification of vector mosquitoes in Zhejiang, China
Real-time dynamic monitoring and multiplex PCR identification of vector mosquitoes in Zhejiang, China Open
The monitoring and identification of mosquito vectors are crucial for controlling the transmission of mosquito-borne diseases. Traditional mosquito morphological identification and surveillance methods, such as human landing catches, human…
View article: Organoid technologies in antitumor drug screening: past development, present applications, and future prospects
Organoid technologies in antitumor drug screening: past development, present applications, and future prospects Open
Tumors are one of the major diseases affecting human life and health with an increasing incidence worldwide. Drug therapy is the most commonly used treatment for tumors. Therefore, screening for antitumor drugs has always been a focus of t…
View article: Pan-cancer analysis reveals TRA16 as a master regulator of human carcinogenesis
Pan-cancer analysis reveals TRA16 as a master regulator of human carcinogenesis Open
Introduction The nuclear receptor TR4 binding protein, TRA16, has been implicated in lung carcinogenesis; however, its broader role across diverse human cancers remains poorly understood. Understanding TRA16’s involvement in cancer biology…
View article: Bacteria-Assisted Celastrol Liposomes for Effective Chemotherapy Against Lung Cancer in Mice Model
Bacteria-Assisted Celastrol Liposomes for Effective Chemotherapy Against Lung Cancer in Mice Model Open
In our work, Bif@CLC-LP significantly inhibited tumor growth while minimizing celastrol-induced liver damage in a mouse lung cancer model. This bacteria-mediated liposome delivery system is a promising new nanoplatform for treating differe…
View article: GM-MoE: Low-Light Enhancement with Gated-Mechanism Mixture-of-Experts
GM-MoE: Low-Light Enhancement with Gated-Mechanism Mixture-of-Experts Open
Low-light enhancement has wide applications in autonomous driving, 3D reconstruction, remote sensing, surveillance, and so on, which can significantly improve information utilization. However, most existing methods lack generalization and …
View article: Time series analysis and scaling law characteristics of viral hepatitis from 2004 to 2023 in Zhejiang Province, China
Time series analysis and scaling law characteristics of viral hepatitis from 2004 to 2023 in Zhejiang Province, China Open
Background Hepatitis significantly increases the global disease burden and has become a major public health issue worldwide. China is a high-risk area for viral hepatitis, which is also a serious public health problem. Methods The scaling …
View article: Soil quality assessment of greenhouse vegetable production in Ningxia—A low‐contaminated and high‐quality crop base
Soil quality assessment of greenhouse vegetable production in Ningxia—A low‐contaminated and high‐quality crop base Open
Declining soil nutrients and increasing total metals impair optimum land productivity. Understanding the spatial and temporal variabilities of soil properties helps researchers and farmers to determine the soil's ecological status and prov…
View article: Bioinformatics analysis reveals novel tumor antigens and immune subtypes of skin cutaneous melanoma contributing to mRNA vaccine development
Bioinformatics analysis reveals novel tumor antigens and immune subtypes of skin cutaneous melanoma contributing to mRNA vaccine development Open
Introduction Skin cutaneous melanoma (SKCM) is a common malignant skin cancer with high mortality and recurrence rates. Although the mRNA vaccine is a promising strategy for cancer treatment, its application against SKCM remains confusing.…
View article: The emerging role of transmembrane proteins in tumorigenesis and therapy
The emerging role of transmembrane proteins in tumorigenesis and therapy Open
Transmembrane proteins (TMEMs) are a kind of proteins that can cross the phospholipid bilayer one or multiple times and remain permanently anchored. They are involved in the regulation of many biological functions, and their dysregulation …
View article: Stratified Impact of Therapies on Anaplastic Thyroid Cancer Outcomes in the Pre-Gene-Targeted Therapy Era
Stratified Impact of Therapies on Anaplastic Thyroid Cancer Outcomes in the Pre-Gene-Targeted Therapy Era Open
Background Anaplastic thyroid cancer (ATC) is a highly lethal disease, often diagnosed with advanced locoregional and distant metastases, resulting in a median survival of just 3–5 months. This study determines the stratified effectiveness…
View article: Highly effective treatment of bacterial infection-accompanied wounds by fat extract-embedded phototherapeutic hydrogel
Highly effective treatment of bacterial infection-accompanied wounds by fat extract-embedded phototherapeutic hydrogel Open
Phototherapy presents an effective approach for treating localized methicillin-resistant Staphylococcus aureus (MRSA) infections; however, the tradeoff between therapeutic efficacy and negative off-target effect persists. To address these …
View article: Global burden of pneumoconiosis attributable to occupational particulate matter, gasses, and fumes from 1990~2021 and forecasting the future trends: a population-based study
Global burden of pneumoconiosis attributable to occupational particulate matter, gasses, and fumes from 1990~2021 and forecasting the future trends: a population-based study Open
Background This study aimed to quantify the global impact of pneumoconiosis resulting from occupational exposure to particulate matter, gasses, and fumes from 1990 to 2021, utilizing data from the Global Burden of Disease Study 2021. Metho…
View article: Hypoxia-induced exosomal lncRNA-PVT1 as a biomarker and mediator of EMT in hepatocellular carcinoma
Hypoxia-induced exosomal lncRNA-PVT1 as a biomarker and mediator of EMT in hepatocellular carcinoma Open
Plasma exosomal lncRNA-PVT1 expression is upregulated in highly invasive cells post-hypoxia, potentially serving as a biomarker for evaluating liver cancer prognosis after TACE. Through a miRNA-345-5p-mediated competing endogenous RNA mech…