Verena Hammelmann
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View article: The Concise Guide to PHARMACOLOGY 2023/24: Ion channels
The Concise Guide to PHARMACOLOGY 2023/24: Ion channels Open
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and over 6000…
View article: Cyclic nucleotide-regulated channels (CNG) in GtoPdb v.2023.1
Cyclic nucleotide-regulated channels (CNG) in GtoPdb v.2023.1 Open
Cyclic nucleotide-gated (CNG) channels are responsible for signalling in the primary sensory cells of the vertebrate visual and olfactory systems. CNG channels are voltage-independent cation channels formed as tetramers. Each subunit has 6…
View article: THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Ion channels
THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Ion channels Open
The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasi…
View article: Cyclic nucleotide-regulated channels (CNG) in GtoPdb v.2021.3
Cyclic nucleotide-regulated channels (CNG) in GtoPdb v.2021.3 Open
Cyclic nucleotide-gated (CNG) channels are responsible for signalling in the primary sensory cells of the vertebrate visual and olfactory systems. CNG channels are voltage-independent cation channels formed as tetramers. Each subunit has 6…
View article: Cyclic nucleotide-regulated channels (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database
Cyclic nucleotide-regulated channels (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database Open
Cyclic nucleotide-gated (CNG) channels are responsible for signalling in the primary sensory cells of the vertebrate visual and olfactory systems.CNG channels are voltage-independent cation channels formed as tetramers. Each subunit has 6T…
View article: Abolishing cAMP sensitivity in HCN2 pacemaker channels induces generalized seizures
Abolishing cAMP sensitivity in HCN2 pacemaker channels induces generalized seizures Open
Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are dually gated channels that are operated by voltage and by neurotransmitters via the cAMP system. cAMP-dependent HCN regulation has been proposed to play a key role in r…
View article: Disturbed Processing of Contextual Information in HCN3 Channel Deficient Mice
Disturbed Processing of Contextual Information in HCN3 Channel Deficient Mice Open
Hyperpolarization-activated cyclic nucleotide-gated channels (HCNs) in the nervous system are implicated in a variety of neuronal functions including learning and memory, regulation of vigilance states and pain. Dysfunctions or genetic los…
View article: AAV Vectors for FRET-Based Analysis of Protein-Protein Interactions in Photoreceptor Outer Segments
AAV Vectors for FRET-Based Analysis of Protein-Protein Interactions in Photoreceptor Outer Segments Open
Fluorescence resonance energy transfer (FRET) is a powerful method for the detection and quantification of stationary and dynamic protein-protein interactions. Technical limitations have hampered systematic in vivo FRET experiments to stud…