Veronica Galli
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View article: Immunomodulatory effects of dental pulp stem cells on lymphocytes and monocytes from patients with rheumatoid arthritis
Immunomodulatory effects of dental pulp stem cells on lymphocytes and monocytes from patients with rheumatoid arthritis Open
The overexpression of inhibitory immune checkpoints by DPSCs may contribute to their immunomodulatory effects. DPSCs modulated a broader range of cytokines in monocyte supernatants compared to lymphocytes.
View article: Colchicine treatment in amyotrophic lateral sclerosis: safety, biological and clinical effects in a randomized clinical trial
Colchicine treatment in amyotrophic lateral sclerosis: safety, biological and clinical effects in a randomized clinical trial Open
In preclinical studies, the anti-inflammatory drug colchicine, which has never been tested in amyotrophic lateral sclerosis, enhanced the expression of autophagy factors and inhibited accumulation of transactive response DNA-binding protei…
View article: In Vivo Treatment with Insulin-like Growth Factor 1 Reduces CCR5 Expression on Vaccine-Induced Activated CD4+ T-Cells
In Vivo Treatment with Insulin-like Growth Factor 1 Reduces CCR5 Expression on Vaccine-Induced Activated CD4+ T-Cells Open
At the heart of the DNA/ALVAC/gp120/alum vaccine’s efficacy in the absence of neutralizing antibodies is a delicate balance of pro- and anti-inflammatory immune responses that effectively decreases the risk of SIVmac251 acquisition in maca…
View article: Comparable cytokine release ex-vivo by whole blood from COVID-19 patients with and without non-invasive ventilation
Comparable cytokine release ex-vivo by whole blood from COVID-19 patients with and without non-invasive ventilation Open
View article: HIV vaccine candidate efficacy in female macaques mediated by cAMP-dependent efferocytosis and V2-specific ADCC
HIV vaccine candidate efficacy in female macaques mediated by cAMP-dependent efferocytosis and V2-specific ADCC Open
View article: NK cells and monocytes modulate primary HTLV-1 infection
NK cells and monocytes modulate primary HTLV-1 infection Open
We investigated the impact of monocytes, NK cells, and CD8 + T-cells in primary HTLV-1 infection by depleting cell subsets and exposing macaques to either HTLV-1 wild type (HTLV-1 WT ) or to the HTLV-1 p12KO mutant unable to infect replete…
View article: Germinal epimutation of Fragile Histidine Triad (FHIT) gene is associated with progression to acute and chronic adult T-cell leukemia diseases
Germinal epimutation of Fragile Histidine Triad (FHIT) gene is associated with progression to acute and chronic adult T-cell leukemia diseases Open
Background Human T cell Leukemia virus type 1 (HTLV-I) is etiologically linked to adult T cell leukemia/lymphoma (ATL) and an inflammatory neurodegenerative disease called HTLV-I-associated myelopathy or tropical spastic paraparesis (HAM/T…
View article: Small heat-shock protein HSPB3 promotes myogenesis by regulating the lamin B receptor
Small heat-shock protein HSPB3 promotes myogenesis by regulating the lamin B receptor Open
View article: Small heat-shock protein HSPB3 promotes myogenesis by regulating the lamin B receptor.
Small heat-shock protein HSPB3 promotes myogenesis by regulating the lamin B receptor. Open
View article: Hsp90‐mediated regulation of DYRK3 couples stress granule disassembly and growth via mTORC1 signaling
Hsp90‐mediated regulation of DYRK3 couples stress granule disassembly and growth via mTORC1 signaling Open
View article: Anti-V2 antibodies virus vulnerability revealed by envelope V1 deletion in HIV vaccine candidates
Anti-V2 antibodies virus vulnerability revealed by envelope V1 deletion in HIV vaccine candidates Open
The efficacy of ALVAC-based HIV and SIV vaccines in humans and macaques correlates with antibodies to envelope variable region 2 (V2). We show here that vaccine-induced antibodies to SIV variable region 1 (V1) inhibit anti-V2 antibody-medi…
View article: BAG3 and BAG6 differentially affect the dynamics of stress granules by targeting distinct subsets of defective polypeptides released from ribosomes
BAG3 and BAG6 differentially affect the dynamics of stress granules by targeting distinct subsets of defective polypeptides released from ribosomes Open
View article: Correction: ALVAC-HIV B/C candidate HIV vaccine efficacy dependent on neutralization profile of challenge virus and adjuvant dose and type
Correction: ALVAC-HIV B/C candidate HIV vaccine efficacy dependent on neutralization profile of challenge virus and adjuvant dose and type Open
[This corrects the article DOI: 10.1371/journal.ppat.1008121.].
View article: Engagement of monocytes, NK cells, and CD4+ Th1 cells by ALVAC-SIV vaccination results in a decreased risk of SIVmac251 vaginal acquisition
Engagement of monocytes, NK cells, and CD4+ Th1 cells by ALVAC-SIV vaccination results in a decreased risk of SIVmac251 vaginal acquisition Open
The recombinant Canarypox ALVAC-HIV/gp120/alum vaccine regimen was the first to significantly decrease the risk of HIV acquisition in humans, with equal effectiveness in both males and females. Similarly, an equivalent SIV-based ALVAC vacc…
View article: Anti-V2 Antibodies Virus Vulnerability Revealed by Envelope V1 Deletion in HIV Vaccine Candidates
Anti-V2 Antibodies Virus Vulnerability Revealed by Envelope V1 Deletion in HIV Vaccine Candidates Open
View article: ALVAC-HIV B/C candidate HIV vaccine efficacy dependent on neutralization profile of challenge virus and adjuvant dose and type
ALVAC-HIV B/C candidate HIV vaccine efficacy dependent on neutralization profile of challenge virus and adjuvant dose and type Open
The ALVAC-HIV clade B/AE and equivalent SIV-based/gp120 + Alum vaccines successfully decreased the risk of virus acquisition in humans and macaques. Here, we tested the efficacy of HIV clade B/C ALVAC/gp120 vaccine candidates + MF59 or dif…
View article: p30 protein: a critical regulator of HTLV-1 viral latency and host immunity
p30 protein: a critical regulator of HTLV-1 viral latency and host immunity Open
View article: Role of HTLV-1 orf-I encoded proteins in viral transmission and persistence
Role of HTLV-1 orf-I encoded proteins in viral transmission and persistence Open
View article: Essential Role of Human T Cell Leukemia Virus Type 1 <i>orf-I</i> in Lethal Proliferation of CD4 <sup>+</sup> Cells in Humanized Mice
Essential Role of Human T Cell Leukemia Virus Type 1 <i>orf-I</i> in Lethal Proliferation of CD4 <sup>+</sup> Cells in Humanized Mice Open
Humanized mice constitute a useful model for studying the HTLV-1-associated polyclonal proliferation of CD4 + T cells and viral integration sites in the human genome. The rapid death of infected animals, however, appears to preclude the cl…
View article: Schifanella SHIVC All Data.xlsx
Schifanella SHIVC All Data.xlsx Open
Complete Dataset for Schifanella Manuscript
View article: Pomalidomide increases immune surface marker expression and immune recognition of oncovirus-infected cells
Pomalidomide increases immune surface marker expression and immune recognition of oncovirus-infected cells Open
Most chronic viruses evade T-cell and natural killer (NK) immunity through downregulation of immune surface markers. Previously we showed that Pomalidomide (Pom) increases surface expression of major histocompatibility complex class I (MHC…
View article: Inhibition of Tunneling Nanotube (TNT) Formation and Human T-cell Leukemia Virus Type 1 (HTLV-1) Transmission by Cytarabine
Inhibition of Tunneling Nanotube (TNT) Formation and Human T-cell Leukemia Virus Type 1 (HTLV-1) Transmission by Cytarabine Open
View article: HIV vaccine candidate activation of hypoxia and the inflammasome in CD14+ monocytes is associated with a decreased risk of SIVmac251 acquisition
HIV vaccine candidate activation of hypoxia and the inflammasome in CD14+ monocytes is associated with a decreased risk of SIVmac251 acquisition Open
View article: Cerebrospinal fluid anti-Epstein-Barr virus specific oligoclonal IgM and IgG bands in patients with clinically isolated and Guillain-Barré syndrome
Cerebrospinal fluid anti-Epstein-Barr virus specific oligoclonal IgM and IgG bands in patients with clinically isolated and Guillain-Barré syndrome Open
View article: Human T Cell Leukemia Virus Type 1 Infection of the Three Monocyte Subsets Contributes to Viral Burden in Humans
Human T Cell Leukemia Virus Type 1 Infection of the Three Monocyte Subsets Contributes to Viral Burden in Humans Open
Because the viral DNA burden correlates with disease development, we investigated the contribution of monocyte subsets (classical, intermediate, and nonclassical monocytes) to the total viral burden in 22 human T cell leukemia virus type 1…
View article: Detection of HTLV-1 replication and CD4+ proliferation in the humanized BLT mouse model
Detection of HTLV-1 replication and CD4+ proliferation in the humanized BLT mouse model Open
View article: HTLV-1 burden dependent on hijacking monocytes chemotaxis
HTLV-1 burden dependent on hijacking monocytes chemotaxis Open
The HTLV-DNA burden in PBMCs is a risk factor for HAM/TSP and ATL development. We investigated the contribution of monocyte subsets (classical, intermediate and non-classical) to the total viral burden in 23 HTLV-1 infected individuals by …
View article: Cerebrospinal fluid CXCL13 in clinically isolated syndrome patients: Association with oligoclonal IgM bands and prediction of Multiple Sclerosis diagnosis
Cerebrospinal fluid CXCL13 in clinically isolated syndrome patients: Association with oligoclonal IgM bands and prediction of Multiple Sclerosis diagnosis Open