Vesa K. Kontinen
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View article: Does cytochrome <scp>2D6</scp> genotype affect the analgesic efficacy of codeine after ambulatory surgery? Prospective trial in 987 adults
Does cytochrome <span>2D6</span> genotype affect the analgesic efficacy of codeine after ambulatory surgery? Prospective trial in 987 adults Open
Background Paracetamol–codeine combination tablet is widely used in pain management after day surgery. For safety reasons, its use has decreased in recent years. Codeine is a prodrug metabolised in the liver by the cytochrome P450 2D6 (CYP…
View article: Factors associated with failed epidural blood patch after accidental dural puncture in obstetrics: a prospective, multicentre, international cohort study
Factors associated with failed epidural blood patch after accidental dural puncture in obstetrics: a prospective, multicentre, international cohort study Open
View article: Purely ropivacaine-based TEA vs single TAP block in pain management after elective laparoscopic colon surgery within an upgraded institutional ERAS program
Purely ropivacaine-based TEA vs single TAP block in pain management after elective laparoscopic colon surgery within an upgraded institutional ERAS program Open
View article: S-ketamine in patient-controlled analgesia reduces opioid consumption in a dose-dependent manner after major lumbar fusion surgery: a randomized, double-blind, placebo-controlled clinical trial
S-ketamine in patient-controlled analgesia reduces opioid consumption in a dose-dependent manner after major lumbar fusion surgery: a randomized, double-blind, placebo-controlled clinical trial Open
BACKGROUND Spinal fusion surgery causes severe pain. Strong opioids, commonly used as postoperative analgesics, may have unwanted side effects. S-ketamine may be an effective analgesic adjuvant in opioid patient-controlled analgesia (PCA).…
View article: Säilyttäkää erikoisalamme yhtenäisyys
Säilyttäkää erikoisalamme yhtenäisyys Open
View article: Systematic review of analgesics and dexamethasone for post-tonsillectomy pain in adults
Systematic review of analgesics and dexamethasone for post-tonsillectomy pain in adults Open
View article: The Yaksh-model of intrathecal opioid-studies: still exciting four decades later
The Yaksh-model of intrathecal opioid-studies: still exciting four decades later Open
View article: Perioperative intravenous ketamine for acute postoperative pain in adults
Perioperative intravenous ketamine for acute postoperative pain in adults Open
Perioperative intravenous ketamine probably reduces postoperative analgesic consumption and pain intensity. Results were consistent in different operation types or timing of ketamine administration, with larger and smaller studies, and by …
View article: Efficacy and safety of epidural, continuous perineural infusion and adjuvant analgesics for acute postoperative pain after major limb amputation – a systematic review
Efficacy and safety of epidural, continuous perineural infusion and adjuvant analgesics for acute postoperative pain after major limb amputation – a systematic review Open
Background and aims: Treatment of pain following major limb amputations is often a clinical challenge in a patient population consisting mainly of elderly with underlying diseases. Literature on management of acute post-amputation pain is …
View article: Kivusta kärsivä syöpäpotilas päivystyksessä
Kivusta kärsivä syöpäpotilas päivystyksessä Open
View article: In memoriam Eeva-Liisa Maunuksela
In memoriam Eeva-Liisa Maunuksela Open
View article: Ketamiini akuutin kivun hoidossa
Ketamiini akuutin kivun hoidossa Open
View article: New approach for treatment of prolonged postoperative pain: APS Out-Patient Clinic
New approach for treatment of prolonged postoperative pain: APS Out-Patient Clinic Open
Background and aims Persistent postoperative pain (PPP) is a significant clinical problem. Several patient-related risk factors for PPP have been identified, including a previous chronic pain problem, young age, female gender and psycholog…
View article: Humanisoidut vasta-ainefragmentit lääkkeinä
Humanisoidut vasta-ainefragmentit lääkkeinä Open
View article: Kivunhoidon näkökulma mukaan opioidikorvaushoitoon
Kivunhoidon näkökulma mukaan opioidikorvaushoitoon Open
View article: Pain outside of the hospital: What is the situation in pre-hospital care, and how could it be improved?
Pain outside of the hospital: What is the situation in pre-hospital care, and how could it be improved? Open
Acute pain research seems to frequently concentrate on postoperative pain studies.Much too often the focus in research is on the immediate postoperative period, when the patient stays conveniently in the post-anaesthesia care unit (PACU), …