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0274 Associations of TNFα Gene Polymorphism with Resilience to Sleep Deprivation and Caffeine Sensitivity Open
Introduction Sleep deprivation degrades the fidelity of human brain information processing, leading to cognitive impairment. Carriers of the A allele of a single nucleotide polymorphism of the TNFα gene (G308A, rs1800629) have been found t…
0290 Caffeine Efficacy Varies as a Function of Individual Vulnerability to Sleep Restriction Open
Introduction We previously showed that relative to placebo (PL), caffeine (CAF) significantly improved psychomotor vigilance task (PVT) reaction time (RT) during the first 2 days (ACUTE phase), but not during the last 3 days (CHRONIC phase…
View article: 1028 Sleep and Enteric Disease: Sleep Now for Less Diarrhea Later
1028 Sleep and Enteric Disease: Sleep Now for Less Diarrhea Later Open
Introduction The bi-directional relationship between sleep and immune function is well-established. Sufficient sleep supports immune health and can increase vaccine efficacy. Conversely, sickness can disturb sleep quality, which can delay …
0199 Sleep and Risk Taking Behavior in United States Army Soldiers: A Four Study Mega-Analysis Open
Introduction In military service members, high risk-taking behavior (RTB; e.g., looking to start a fight, reckless driving) leads to injury, judicial reprimand, and removal from military service. Consequently, reducing RTB has become a pri…
0204 Advantage Of Single-effort Ultra-marathons To Examine Homeostatic Loads And Circadian Properties Of Human Endurance Under Total Sleep Deprivation Open
There a few field studies that have examined human performance dynamics under total sleep deprivation. Here, the logistics of a single-effort ultra-marathon provided us with the opportunity to dissect the homeostatic loads and circadian pr…
0301 Sleep Deprivation Unmasks Performance Deficits Following Mild Traumatic Brain Injury Open
Subjective cognitive complaints are common in the chronic stages (>3 months since injury) of mTBI, yet there is limited evidence of objective neurocognitive deficits in this population. Neuroimaging studies have demonstrated that although …
0751 EXPLORING SELF-REPORTED STRESS DURING SLEEP EXTENSION AND SLEEP DEPRIVATION Open
Previous work has demonstrated that sleep loss increases negative mood while sleep extension improves mood. Though these studies have assessed multiple dimensions of mood, few have specifically targeted emotional stress. This is the first …
View article: 0073 DYNAMIC CHANGES IN HUMAN INNATE AND ADAPTIVE IMMUNE CELL NUMBERS IN RESPONSE TO SLEEP EXTENSION AND SLEEP DEPRIVATION
0073 DYNAMIC CHANGES IN HUMAN INNATE AND ADAPTIVE IMMUNE CELL NUMBERS IN RESPONSE TO SLEEP EXTENSION AND SLEEP DEPRIVATION Open
It has not been determined if innate and adaptive immune cell counts change following sleep extension (EXT). Here, we combine 2-days of baseline (8 h time-in-bed), 1-week of EXT (10 h time-in-bed) immediately followed by sleep deprivation …
0805 THE ROLE OF SLEEP EXTENSION AND DEPRIVATION ON EMOTIONAL ATTENTIONAL BIASES IN HEALTHY ADULTS Open
Previous research has revealed that some pathologies display exaggerated bias towards threatening stimuli, particularly in individuals with anxiety and trauma related disorders compared to normal controls. Sleep loss is often associated wi…
1174 SLEEP ARCHITECTURE FOLLOWING TRAUMATIC BRAIN INJURY: A SYSTEMATIC REVIEW AND META-ANALYSIS Open
Sleep architecture alterations are present soon after traumatic brain injury (TBI), but what remains less clear is whether these alterations persist chronically (long-term) after injury. It is important to identify whether sleep architectu…
0807 COMPARING MOOD FOLLOWING SLEEP EXTENSION AND SLEEP DEPRIVATION Open
The Profile of Mood States (POMS) scale is a validated measure that assesses changes in mood across different domains. Sleep deprivation studies in particular have shown increases in negative mood subscales of the POMS. In contrast, sleep …
0269 INSOMNIA, SHORT SLEEP DURATION, AND FAILED TEST PERFORMANCE IN A MILITARY ACADEMIC SETTING Open
College age students often obtain poor sleep and experience adverse physical and mental health outcomes as a result, which may, in turn, impact their academic performance. However, little is known about the relationships between sleep, wel…
0177 THE TRAIT OF INTROVERSION-EXTRAVERSION CONTRIBUTES TO SUSTAINED PERFORMANCE ON PLANNING AND SEQUENCING ABILITIES DURING SLEEP DEPRIVATION Open
The existence of consistent trait-like inter-individual differences in the ability to sustain objective psychomotor vigilance and subjective alertness during periods of sleep deprivation has been well established. However, it has proven di…