Vibeke Andersen
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View article: Long-term Disease Course of Crohn’s Disease in a Prospective European Population-based Inception Cohort: An Epi-IBD Cohort Study
Long-term Disease Course of Crohn’s Disease in a Prospective European Population-based Inception Cohort: An Epi-IBD Cohort Study Open
Despite earlier and more frequent use of advanced therapies in Western Europe, no differences in disease outcomes were observed between Western and Eastern European patients. Ten years after diagnosis, one-in-five patients with uncomplicat…
View article: Gut Mycobiome in Inflammatory Bowel Disease: A Systematic Review of Case-Control Studies
Gut Mycobiome in Inflammatory Bowel Disease: A Systematic Review of Case-Control Studies Open
Background The bacterial composition of the microbiome in inflammatory bowel disease (IBD) has been the focus of substantial interest. In contrast, the fungal part of the microbiome, the mycobiome, has only rarely been investigated—althoug…
View article: A Longitudinal Post-authorization Safety Study of Golimumab in Treatment of Ulcerative Colitis: A Cohort Study in Denmark and Sweden, 2013–2021
A Longitudinal Post-authorization Safety Study of Golimumab in Treatment of Ulcerative Colitis: A Cohort Study in Denmark and Sweden, 2013–2021 Open
View article: Advancing Inflammatory Bowel Disease Treatment by Targeting the Innate Immune System and Precision Drug Delivery
Advancing Inflammatory Bowel Disease Treatment by Targeting the Innate Immune System and Precision Drug Delivery Open
Inflammatory bowel disease (IBD), encompassing Crohn’s disease and ulcerative colitis, involves chronic inflammation of the gastrointestinal tract. Current immune-modulating therapies are insufficient for 30–50% of patients or cause signif…
View article: Food Is Medicine: Diet Assessment Tools in Adult Inflammatory Bowel Disease Research
Food Is Medicine: Diet Assessment Tools in Adult Inflammatory Bowel Disease Research Open
Background: Diet significantly impacts the onset and progression of inflammatory bowel disease (IBD), and diet offers unique opportunities for treatment and preventative purposes. However, despite growing interest, no diet has been conclus…
View article: Comparing Environmental Risk Factors at Diagnosis in Faroese and Danish Patients with Inflammatory Bowel Disease
Comparing Environmental Risk Factors at Diagnosis in Faroese and Danish Patients with Inflammatory Bowel Disease Open
View article: Microfibrillar-associated protein 4 as a predictive biomarker of treatment response in patients with chronic inflammatory diseases initiating biologics: secondary analyses based on the prospective BELIEVE cohort study
Microfibrillar-associated protein 4 as a predictive biomarker of treatment response in patients with chronic inflammatory diseases initiating biologics: secondary analyses based on the prospective BELIEVE cohort study Open
View article: Impact of gluten intake on clinical outcomes in patients with chronic inflammatory diseases initiating biologics: Secondary analysis of the prospective multicentre <scp>BELIEVE</scp> cohort study
Impact of gluten intake on clinical outcomes in patients with chronic inflammatory diseases initiating biologics: Secondary analysis of the prospective multicentre <span>BELIEVE</span> cohort study Open
Chronic inflammatory diseases (CIDs) pose a growing healthcare challenge, with a substantial proportion of patients showing inadequate response to biological treatment. There is renewed interest in dietary changes to optimize treatment reg…
View article: The Association between Genetics and Response to Treatment with Biologics in Patients with Psoriasis, Psoriatic Arthritis, Rheumatoid Arthritis, and Inflammatory Bowel Diseases: A Systematic Review and Meta-Analysis
The Association between Genetics and Response to Treatment with Biologics in Patients with Psoriasis, Psoriatic Arthritis, Rheumatoid Arthritis, and Inflammatory Bowel Diseases: A Systematic Review and Meta-Analysis Open
Genetic biomarkers could potentially lower the risk of treatment failure in chronic inflammatory diseases (CID) like psoriasis, psoriatic arthritis (PsA), rheumatoid arthritis (RA), and inflammatory bowel disease (IBD). We performed a syst…
View article: Assessment of the Inflammatory Effects of Gut Microbiota from Human Twins Discordant for Ulcerative Colitis on Germ-free Mice
Assessment of the Inflammatory Effects of Gut Microbiota from Human Twins Discordant for Ulcerative Colitis on Germ-free Mice Open
Disturbances in gut microbiota are prevalent in inflammatory bowel disease (IBD), which includes ulcerative colitis (UC). However, whether these disturbances contribute to development of the disease or are a result of the disease is unclea…
View article: Meta-analysis of ACE inhibitor–induced angioedema identifies novel risk locus
Meta-analysis of ACE inhibitor–induced angioedema identifies novel risk locus Open
View article: The SYSCID map: a graphical and computational resource of molecular mechanisms across rheumatoid arthritis, systemic lupus erythematosus and inflammatory bowel disease
The SYSCID map: a graphical and computational resource of molecular mechanisms across rheumatoid arthritis, systemic lupus erythematosus and inflammatory bowel disease Open
Chronic inflammatory diseases (CIDs), including inflammatory bowel disease (IBD), rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) are thought to emerge from an impaired complex network of inter- and intracellular biochemic…
View article: Identification of novel genetic loci for risk of multiple myeloma by functional annotation
Identification of novel genetic loci for risk of multiple myeloma by functional annotation Open
View article: Impaired Abcb1a function and red meat in a translational colitis mouse model induces inflammation and alters microbiota composition
Impaired Abcb1a function and red meat in a translational colitis mouse model induces inflammation and alters microbiota composition Open
Inflammatory Bowel Disease (IBD) affects approximately 0.3% of the global population, with incidence rates rising dramatically worldwide. Emerging evidence points to an interplay between exposome factors such as diet and gut microbiota, ho…
View article: HLA-DP on Epithelial Cells Enables Tissue Damage by NKp44+ Natural Killer Cells in Ulcerative Colitis
HLA-DP on Epithelial Cells Enables Tissue Damage by NKp44+ Natural Killer Cells in Ulcerative Colitis Open
View article: Investigating the Crime Scene—Molecular Signatures in Inflammatory Bowel Disease
Investigating the Crime Scene—Molecular Signatures in Inflammatory Bowel Disease Open
Inflammatory bowel diseases (IBD) are without cure and troublesome to manage because of the considerable diversity between patients and the lack of reliable biomarkers. Several studies have demonstrated that diet, gut microbiota, genetics …
View article: Impact of sex and socioeconomic status on risk of surgery, hospitalization, and use of medications in inflammatory bowel disease: A systematic review and meta-analysis
Impact of sex and socioeconomic status on risk of surgery, hospitalization, and use of medications in inflammatory bowel disease: A systematic review and meta-analysis Open
Background Inflammatory bowel diseases (IBDs) are often associated with high healthcare utilisation. This systematic review aimed to summarize what is known about the impact of sex, income, and education on the risk of bowel surgery, hospi…
View article: Treatment of Chronic Inflammatory Diseases – The Potential of Pharmacogenetics
Treatment of Chronic Inflammatory Diseases – The Potential of Pharmacogenetics Open
Given the substantial degree of inter-individual variability in treatment responses in patients with inflammatory bowel disease (IBD), treatment optimization is warranted. We provide an overview of pharmacogenetic variants that can affect …
View article: Genetic architecture of the inflammatory bowel diseases across East Asian and European ancestries
Genetic architecture of the inflammatory bowel diseases across East Asian and European ancestries Open
View article: The Danish-American Research Exchange (DARE): a cross-sectional study of a binational research education program
The Danish-American Research Exchange (DARE): a cross-sectional study of a binational research education program Open
Background Most medical educational programs emphasize clinical observation or clinical skill acquisition, fewer focus upon research. The Danish-American Research Exchange (DARE) program, sponsored by the Lundbeck Foundation, is unique in …
View article: P124 Risk of surgery in inflammatory bowel disease: A systematic review and meta-analysis of sex-based differences
P124 Risk of surgery in inflammatory bowel disease: A systematic review and meta-analysis of sex-based differences Open
Background Inflammatory bowel diseases (IBDs) are chronic diseases that require routine hospital visits and long-term medical treatment for control of disease activity. Factors such as gender may impact the use and need for healthcare. Thi…
View article: P875 Disease course of Ulcerative Colitis during the first ten years following diagnosis in a prospective European population-based inception cohort – the Epi-IBD cohort
P875 Disease course of Ulcerative Colitis during the first ten years following diagnosis in a prospective European population-based inception cohort – the Epi-IBD cohort Open
Background The Epi-IBD cohort is a prospective European population-based cohort of 1,390 patients diagnosed in 2010 and 2011 with inflammatory bowel disease (IBD) according to Copenhagen criteria in centres from Eastern and Western Europea…
View article: OP18 Disease course of Crohn’s disease during the first ten years following diagnosis in a prospective European population-based inception cohort – the Epi-IBD cohort
OP18 Disease course of Crohn’s disease during the first ten years following diagnosis in a prospective European population-based inception cohort – the Epi-IBD cohort Open
Background The Epi-IBD cohort is a prospective European population-based cohort of 1,390 patients diagnosed in 2010 and 2011 with inflammatory bowel disease (IBD) according to Copenhagen criteria in centres from Eastern and Western Europea…
View article: Additional file 3 of The Danish-American Research Exchange (DARE): a cross-sectional study of a binational research education program
Additional file 3 of The Danish-American Research Exchange (DARE): a cross-sectional study of a binational research education program Open
Additional file 3: Supplemental Table 1. Qualitative data from DARE medical student alumni collected at two focus group meetings. Appendix 1. References for publications of DARE Fellows and Alumni, 2015-2020, Cohorts 1-5.
View article: Gluten Degradation by the Gut Microbiota of Ulcerative Colitis Patients
Gluten Degradation by the Gut Microbiota of Ulcerative Colitis Patients Open
Several studies have reported improved disease symptomatology in ulcerative colitis (UC) patients consuming a gluten free diet. This observation coupled with diversity depletion in the gut microbiota of UC patients led us to hypothesize th…
View article: Impact of fibre and red/processed meat intake on treatment outcomes among patients with chronic inflammatory diseases initiating biological therapy: A prospective cohort study
Impact of fibre and red/processed meat intake on treatment outcomes among patients with chronic inflammatory diseases initiating biological therapy: A prospective cohort study Open
Background Biologic disease-modifying drugs have revolutionised the treatment of a number of chronic inflammatory diseases (CID). However, up to 60% of the patients do not have a sufficient response to treatment and there is a need for opt…
View article: Author index
Author index Open
View article: Inflammatory potential of gut microbiota from monozygotic twin pair discordant for ulcerative colitis
Inflammatory potential of gut microbiota from monozygotic twin pair discordant for ulcerative colitis Open
Gut microbiota perturbations are common in inflammatory bowel disease (IBD), including ulcerative colitis (UC), but it is unclear whether this is a result of the disease or a contributing factor. In twin pairs discordant for IBD, the healt…
View article: Additional file 1 of Longitudinal multi-omics analysis identifies early blood-based predictors of anti-TNF therapy response in inflammatory bowel disease
Additional file 1 of Longitudinal multi-omics analysis identifies early blood-based predictors of anti-TNF therapy response in inflammatory bowel disease Open
Additional file 1: Table S1. Sampling scheme and samples used for the study.
View article: High-fat meals do not affect thrombin formation and fibrin clot lysis in individuals with obesity during intentional weight loss
High-fat meals do not affect thrombin formation and fibrin clot lysis in individuals with obesity during intentional weight loss Open