Qian Wu
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View article: Protocol for the Preparation of Polyphenols‐Polysaccharide Nanoparticles
Protocol for the Preparation of Polyphenols‐Polysaccharide Nanoparticles Open
Polyphenols, natural compounds abundantly distributed in plants, possess potent antioxidant and anti‐inflammatory activities and hold promising potential in cardiovascular protection and the management of metabolic disorders. Nevertheless,…
View article: Unraveling the mysteries of schizophrenia: Insights into prefrontal cortex dysfunction and therapeutic implications
Unraveling the mysteries of schizophrenia: Insights into prefrontal cortex dysfunction and therapeutic implications Open
Schizophrenia is a multifaceted neurodevelopmental disorder characterized by hallucinations, delusions, cognitive deficits, and emotional dysregulation. The prefrontal cortex (PFC), essential for executive functions, working memory, and em…
View article: High Serum Phosphate Promotes Cognitive Impairment in Uremic Rats via Mediating Vascular Calcification
High Serum Phosphate Promotes Cognitive Impairment in Uremic Rats via Mediating Vascular Calcification Open
Introduction: Cognitive impairment (CI) is common in patients with end-stage renal disease, but the mechanism of uremia-associated CI is poorly recognized. Methods: In this study, we constructed uremic rat models, treated with high-level p…
View article: Guideline for the Detection of Advanced Glycation End Products
Guideline for the Detection of Advanced Glycation End Products Open
Advanced glycation end products (AGEs), stable products of nonenzymatic reactions between reducing sugars and biological macromolecules, are widely present in biological tissues and processed foods. Their aberrant accumulation links to chr…
View article: Progressively reduced cerebral oxygen metabolism and elevated plasma NfL levels in the zQ175DN mouse model of Huntington's disease
Progressively reduced cerebral oxygen metabolism and elevated plasma NfL levels in the zQ175DN mouse model of Huntington's disease Open
Huntington's disease (HD) is a progressive neurodegenerative disorder caused by a CAG-repeat expansion in exon-1 of the huntingtin gene. Currently, no disease-modifying therapies are available, with a significant challenge in evaluating th…
View article: Modulation of Aging Diseases via RAGE Targets: A Dietary Intervention Review
Modulation of Aging Diseases via RAGE Targets: A Dietary Intervention Review Open
With the acceleration of global population aging, effective strategies for the prevention and management of aging‐related diseases have become increasingly urgent. The receptor for advanced glycation end products (RAGE), a pattern recognit…
View article: Screening of lotus aromatic raw materials based on flowering stages and floral organs
Screening of lotus aromatic raw materials based on flowering stages and floral organs Open
Lotus (Nelumbo spp.) is a valuable plant resource with promising applications in the cosmetic and food industries. To effectively utilize the aromatic compounds of lotus flowers, it is essential to clarify the optimal harvesting organ and …
View article: Effect of mineralizer on the synthesis of (Ni, Mn) co-doping CuFe5O8 pigment and its glazing performance
Effect of mineralizer on the synthesis of (Ni, Mn) co-doping CuFe5O8 pigment and its glazing performance Open
Novel Co and Cr free, high-temperature (Ni, Mn) co-doping CuFe5O8 black ceramic pigments were synthesized. The effects of mineralizer type and mineralizer amount on the synthesis and coloration of (Ni, Mn) co-doping CuFe5O8 pigments, as we…
View article: Untargeted metabolites profiling of volatile components of Chinese Antique Lotus (<i>Nelumbo nucifera</i> Gaertn.) using solid-phase microextraction (SPME) GC/MS
Untargeted metabolites profiling of volatile components of Chinese Antique Lotus (<i>Nelumbo nucifera</i> Gaertn.) using solid-phase microextraction (SPME) GC/MS Open
Floral scent is a crucial characteristic that significantly influences reproductive processes and indicates the ornamental value of many plants. Antique Lotus ( Nelumbo) , an important ornamental germplasm, has high archaeological and cult…
View article: Recent advances in crocodilian oil research: bioactive components and potential therapeutic applications
Recent advances in crocodilian oil research: bioactive components and potential therapeutic applications Open
The economic value of crocodilian farming has risen substantially in recent years, drawing increasing attention to crocodilian oil as a traditional natural remedy rich in diverse bioactive constituents. Despite its therapeutic potential, c…
View article: Interfacial Stabilization of Green and Food-Safe Emulsions through Complexation of Tannic Acid and Nanochitins
Interfacial Stabilization of Green and Food-Safe Emulsions through Complexation of Tannic Acid and Nanochitins Open
Nanochitins exhibit unique structural attributes that confer distinct physical properties to multiphase systems. Amphiphilic tannic acid (TA) serves as an excellent candidate for interfacial modification via electrostatic adsorption and co…
View article: Progressively reduced cerebral oxygen metabolism and elevated plasma NfL levels in the zQ175DN mouse model of Huntington’s disease
Progressively reduced cerebral oxygen metabolism and elevated plasma NfL levels in the zQ175DN mouse model of Huntington’s disease Open
Huntington’s disease (HD) is a progressive neurodegenerative disorder caused by a CAG-repeat expansion in exon-1 of the huntingtin gene. Currently, no disease-modifying therapies are available, with a significant challenge in evaluating th…
View article: Preparation of a Novel Yeast Protein‐Based Shrimp With Addition of Lotus Seedpod Procyanidins as an Anti‐Glycation Agent
Preparation of a Novel Yeast Protein‐Based Shrimp With Addition of Lotus Seedpod Procyanidins as an Anti‐Glycation Agent Open
This study developed a novel yeast protein‐based shrimp mainly composed of yeast protein (F75), konjac glucomannan (KGM), and lotus seedpod oligomeric procyanidins (LOPC), and its texture, protein content, moisture levels, and anti‐glycati…
View article: A novel high‐protein composite rice with anti‐glycation properties prepared with crushed rice flour, whey protein and lotus seed proanthocyanidins
A novel high‐protein composite rice with anti‐glycation properties prepared with crushed rice flour, whey protein and lotus seed proanthocyanidins Open
In this research, a novel rice composed of grated rice flour, whey protein, and lotus seedpod oligomeric procyanidins was developed through pre‐gelatinization combined with twin‐screw extrusion techniques. The nutritional, physicochemical …
View article: Effects of dietary addition of mulberry leaf powder on blood metabolites and fecal microbiota composition in Hu sheep
Effects of dietary addition of mulberry leaf powder on blood metabolites and fecal microbiota composition in Hu sheep Open
In livestock production, ruminant feed resources are often scarce, and numerous challenges arise during production, such as immune disorders and oxidative stress. Mulberry leaves are rich in various nutrients and exhibit significant antiox…
View article: From risk to chronicity: genetic and neuroimaging insights into the evolving patterns of spontaneous brain activity in schizophrenia
From risk to chronicity: genetic and neuroimaging insights into the evolving patterns of spontaneous brain activity in schizophrenia Open
Background Schizophrenia progresses through high-risk, first-episode, and chronic stages, each associated with altered spontaneous brain activity. Resting state functional MRI studies highlight these changes, but inconsistencies persist, a…
View article: Regulation of aging-related chronic diseases by dietary polyphenols: An updated overview
Regulation of aging-related chronic diseases by dietary polyphenols: An updated overview Open
With the aging of the population, diseases of aging such as Alzheimer's disease, diabetes and coronary heart disease are gradually becoming a key concern in global health. Dietary polyphenols, as a natural antioxidant with biological activ…
View article: A Standardized Mouse Model for Wound Infection with Pseudomonas aeruginosa
A Standardized Mouse Model for Wound Infection with Pseudomonas aeruginosa Open
Pseudomonas aeruginosa is a highly drug-resistant pathogen known to impair wound healing and provoke inflammatory responses, potentially leading to immune dysregulation. This study aimed to systematically investigate the immune response me…
View article: Effects of dietary propyl gallate and Lactobacillus plantarum addition on growth, intestinal morphology, antioxidant capacity, and immune functions of Pekin ducks
Effects of dietary propyl gallate and Lactobacillus plantarum addition on growth, intestinal morphology, antioxidant capacity, and immune functions of Pekin ducks Open
The interaction between probiotic bacteria and polyphenol antioxidants can potentially enhance animal health. The present study examined the effects of propyl gallate and Lactobacillus plantarum supplementation on the growth, intestinal mo…
View article: Thanatin: A Promising Antimicrobial Peptide Targeting the Achilles’ Heel of Multidrug-Resistant Bacteria
Thanatin: A Promising Antimicrobial Peptide Targeting the Achilles’ Heel of Multidrug-Resistant Bacteria Open
Antimicrobial resistance poses an escalating threat to human health, necessitating the development of novel antimicrobial agents capable of addressing challenges posed by antibiotic-resistant bacteria. Thanatin, a 21-amino acid β-hairpin i…
View article: Tumor Cell-Derived Exosomal Hybrid Nanosystems Loaded with Rhubarbic Acid and Tanshinone IIA for Sepsis Treatment
Tumor Cell-Derived Exosomal Hybrid Nanosystems Loaded with Rhubarbic Acid and Tanshinone IIA for Sepsis Treatment Open
R+T/Lipo/EXO presents a promising approach using exosomal hybrid nanosystems for treating sepsis.
View article: Styxl2 regulates de novo sarcomere assembly by binding to non-muscle myosin IIs and promoting their degradation
Styxl2 regulates de novo sarcomere assembly by binding to non-muscle myosin IIs and promoting their degradation Open
Styxl2, a poorly characterized pseudophosphatase, was identified as a transcriptional target of the Jak1-Stat1 pathway during myoblast differentiation in culture. Styxl2 is specifically expressed in vertebrate striated muscles. By gene kno…
View article: The association between dietary vitamin B1 intake and constipation: a population-based study
The association between dietary vitamin B1 intake and constipation: a population-based study Open
Background Numerous researches have indicated a correlation between the intake of dietary micronutrients and the occurrence of constipation. Nevertheless, the correlation between constipation and vitamin B1 remains uninvestigated. The main…