Victor Shpak
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View article: Вузлова патологія у членів Українсько-Американської тиреоїдної когорти: дескриптивний аналіз випадків, вперше виявлених на 2-4 циклах скринінгових обстежень
Вузлова патологія у членів Українсько-Американської тиреоїдної когорти: дескриптивний аналіз випадків, вперше виявлених на 2-4 циклах скринінгових обстежень Open
Резюме. Виявлення вузлів щитоподібної залози (ЩЗ) стає дедалі частішим у клінічній практиці в усьому світі. Переважна більшість новоутворень є доброякісними, рак ЩЗ діагностується приблизно в 4,0-6,5% випадків. Фактори ризику раку і вузлов…
View article: Тренди захворюваності на рак щитоподіб. залози серед дітей та підлітків України, постраждалих внаслідок Чорноб. катастрофи, вплив підвищення проліферативної активності на клініко-гістопатологічні характеристики радіогенних папілярних тиреоїдних карцином
Тренди захворюваності на рак щитоподіб. залози серед дітей та підлітків України, постраждалих внаслідок Чорноб. катастрофи, вплив підвищення проліферативної активності на клініко-гістопатологічні характеристики радіогенних папілярних тиреоїдних карцином Open
Резюме. У статті наведено огляд основних результатів, отриманих за завершеною у 2024 році науково-дослідною роботою (НДР). Метою дослідження було продовжити моніторинг захворюваності на рак щитоподібної залози (РЩЗ) в дітей та підлітків Ук…
View article: Хронологія виконання та перспективи Українсько-Американського тиреоїдного Проєкту
Хронологія виконання та перспективи Українсько-Американського тиреоїдного Проєкту Open
Резюме. Внаслідок аварії на Чорнобильській атомній електростанції (ЧАЕС) значна кількість радіоактивних речовин потрапила в навколишнє середовище. Радіоактивні ізотопи йоду, переважно 131I, стали основним дозоутворювальним фактором для нас…
View article: Thyroid doses for the Chornobyl Tissue Bank: improved estimates based on revised methodology and individual residence and diet history
Thyroid doses for the Chornobyl Tissue Bank: improved estimates based on revised methodology and individual residence and diet history Open
Increased thyroid cancer incidence has been one of the principal adverse health effects of the Chornobyl (Chernobyl) nuclear power plant accident. Accurate dose estimation is critical for assessing the radiation dose-response relationship.…
View article: Analysis of digitalization modern global trends and factors in the context of Ukraine’s agricultural sector
Analysis of digitalization modern global trends and factors in the context of Ukraine’s agricultural sector Open
The article outlines trends, barriers and opportunities for digitalization in Ukraine’s agricultural sector. Due to the rapid information technologies development, digitalization has become a key economic growth factor, particularly in Ukr…
View article: Prevalence of Thyroid Nodules in Residents of Ukraine Exposed as Children or Adolescents to Iodine-131 from the Chornobyl Accident
Prevalence of Thyroid Nodules in Residents of Ukraine Exposed as Children or Adolescents to Iodine-131 from the Chornobyl Accident Open
Background: Although childhood exposure to radioactive iodine-131 (I-131) is an established risk factor for thyroid cancer, evidence for an association with thyroid nodules is less clear. The objective of this study is to eva…
View article: Exposure to the Thyroid from Intake of Radioiodine Isotopes after the Chornobyl Accident. Report I: Revised Doses and Associated Uncertainties for the Ukrainian-American Cohort
Exposure to the Thyroid from Intake of Radioiodine Isotopes after the Chornobyl Accident. Report I: Revised Doses and Associated Uncertainties for the Ukrainian-American Cohort Open
Thyroid doses from intake of radioiodine isotopes (131I, 132Te+132I, and 133I) and associated uncertainties were revised for the 13,204 Ukrainian-American cohort members exposed in childhood and adolescence to fallout from the Chornobyl nu…
View article: Breast cancer risk in Ukrainian women exposed to Chornobyl fallout while pregnant or lactating: standardized incidence ratio analysis, 1998 to 2016
Breast cancer risk in Ukrainian women exposed to Chornobyl fallout while pregnant or lactating: standardized incidence ratio analysis, 1998 to 2016 Open
View article: Breast cancer risk in Ukrainian women exposed to Chornobyl fallout while pregnant or lactating: standardized incidence ratio analysis, 1998 to 2016
Breast cancer risk in Ukrainian women exposed to Chornobyl fallout while pregnant or lactating: standardized incidence ratio analysis, 1998 to 2016 Open
Background The radiation-related risk of breast cancer among women following the Chornobyl accident remains uncertain. During pregnancy, there is rapid cell proliferation in the breast while radioactive iodine from fallout exposure can con…
View article: Assessment of internal exposure to 131I and short-lived radioiodine isotopes and associated uncertainties in the Ukrainian cohort of persons exposed in utero
Assessment of internal exposure to 131I and short-lived radioiodine isotopes and associated uncertainties in the Ukrainian cohort of persons exposed in utero Open
This study revised the thyroid doses for 2582 Ukrainian in utero cohort members exposed to Chornobyl fallout (the Ukrainian in utero cohort) based on revision of: (i) 131I thyroid activity measured in the Ukrainian population, (ii) thyroid…
View article: Reply to letter: Thyroid neoplasia after Chernobyl: A comment
Reply to letter: Thyroid neoplasia after Chernobyl: A comment Open
We thank Dr. Jargin for his interest in our study.1 In his letter, Dr. Jargin suggests that our radiation dose–response findings are biased due to screening, diagnostic, and treatment practices in areas of the former USSR affected by the C…
View article: Thyroid Cancer and Benign Nodules After Exposure<i>In Utero</i>to Fallout From Chernobyl
Thyroid Cancer and Benign Nodules After Exposure<i>In Utero</i>to Fallout From Chernobyl Open
The dose effect by nodule size, with I-131 risk for large but not small nodules, is similar to that among exposed children and adolescents in Belarus. Based on a small number of cases, there is also a suggestive effect of I-131 dose on thy…
View article: Comparative Histopathologic Analysis of “Radiogenic” and “Sporadic” Papillary Thyroid Carcinoma: Patients Born Before and After the Chernobyl Accident
Comparative Histopathologic Analysis of “Radiogenic” and “Sporadic” Papillary Thyroid Carcinoma: Patients Born Before and After the Chernobyl Accident Open
Radiogenic PTC is less likely to demonstrate a dominant papillary growth pattern and more likely to display more aggressive tumor behavior than sporadic PTC. Histopathologic tumor aggressiveness declines with patient age in both radiogenic…
View article: THE MODERN TRENDS OF UKRAINIAN BOOK PUBLISHING
THE MODERN TRENDS OF UKRAINIAN BOOK PUBLISHING Open
This article is intended to highlight some current problems of contemporary publishing as a social and cultural phenomenon as a component of the national information space. The author shows a retrospective of development, ups and downs of …
View article: Neonatal outcomes following exposure in utero to fallout from Chernobyl
Neonatal outcomes following exposure in utero to fallout from Chernobyl Open
View article: Thyroid neoplasia risk is increased nearly 30 years after the Chernobyl accident
Thyroid neoplasia risk is increased nearly 30 years after the Chernobyl accident Open
To evaluate risk of thyroid neoplasia nearly 30 years following exposure to radioactive iodine (I‐131) from the 1986 Chernobyl nuclear accident, we conducted a fifth cycle of thyroid screening of the Ukrainian‐American cohort during 2012–2…
View article: Factors associated with serum thyroglobulin in a Ukrainian cohort exposed to iodine-131 from the accident at the Chernobyl Nuclear Plant
Factors associated with serum thyroglobulin in a Ukrainian cohort exposed to iodine-131 from the accident at the Chernobyl Nuclear Plant Open
View article: METHODOLOGY OF RESEARCH OF PUBLISHING BUSINESS HISTORY
METHODOLOGY OF RESEARCH OF PUBLISHING BUSINESS HISTORY Open
This article is devoted to analysis of the modern methods and methodology of research of publishing business history. The urgency of research is that the printed word is crucial in development of the independent Ukraine. It forms a socio-p…
View article: Integration of a radiation biomarker into modeling of thyroid carcinogenesis and post-Chernobyl risk assessment
Integration of a radiation biomarker into modeling of thyroid carcinogenesis and post-Chernobyl risk assessment Open
Strong evidence for the statistical association between radiation exposure and disease has been produced for thyroid cancer by epidemiological studies after the Chernobyl accident. However, limitations of the epidemiological approach in or…
View article: BOOK PUBLISHING IN UKRAINE: THE FACTORS OF EVELOP
BOOK PUBLISHING IN UKRAINE: THE FACTORS OF EVELOP Open
This article is devoted to analysis of the modern problems of book publishing in the context of national information space. Development of the Ukrainian state is impossible without development of national book publishing, which is a part o…
View article: Histopathological features of papillary thyroid carcinomas detected during four screening examinations of a Ukrainian-American cohort
Histopathological features of papillary thyroid carcinomas detected during four screening examinations of a Ukrainian-American cohort Open
We determined that the invasive properties of PTCs that develop in iodine-131-exposed children may be associated with radiation dose. In addition, based on a subset of cases, tumours with chromosomal rearrangements appear to have a more in…
View article: Dose-dependent expression of CLIP2 in post-Chernobyl papillary thyroid carcinomas
Dose-dependent expression of CLIP2 in post-Chernobyl papillary thyroid carcinomas Open
A previous study on papillary thyroid carcinomas (PTC) in young patients who were exposed to (131)iodine from the Chernobyl fallout revealed an exclusive gain of chromosomal band 7q11.23 in exposed cases compared to an age-matched control …
View article: Non-thyroid cancer in Northern Ukraine in the post-Chernobyl period: Short report
Non-thyroid cancer in Northern Ukraine in the post-Chernobyl period: Short report Open