Victoria Dyster
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View article: Within-host genetic diversity of pneumococcal serotype 3 during one-year prolonged carriage in a healthy adult
Within-host genetic diversity of pneumococcal serotype 3 during one-year prolonged carriage in a healthy adult Open
Streptococcus pneumoniae adapts within hosts through genetic variation and genome plasticity, facilitating persistence under antibiotic and immune pressures. Here, we investigated a prolonged pneumococcal carriage episode (>337 days) in a …
View article: GPS Pipeline: portable, scalable genomic pipeline for Streptococcus pneumoniae surveillance from Global Pneumococcal Sequencing Project
GPS Pipeline: portable, scalable genomic pipeline for Streptococcus pneumoniae surveillance from Global Pneumococcal Sequencing Project Open
Streptococcus pneumoniae (pneumococcus) is a major pathogen globally, responsible for an estimated one million deaths annually and contributing significantly to the global burden of antimicrobial resistance. Ongoing surveillance of its vac…
View article: Within-host pneumococcal serotype 3 genetic diversity and evolution during a one-year prolonged carriage episode in a healthy adult
Within-host pneumococcal serotype 3 genetic diversity and evolution during a one-year prolonged carriage episode in a healthy adult Open
Streptococcus pneumoniae can rapidly evolve within hosts through genetic mutations, recombination, and mobile genetic elements, enabling adaptation to antibiotics and immune pressures. Here, we detail a longitudinal phenotypic and genomic …
View article: 19 Nasopharyngeal resistome under antibiotic pressure; the long-term effects of mass drug administration (MDA) of azithromycin to pre-school children in Malawi
19 Nasopharyngeal resistome under antibiotic pressure; the long-term effects of mass drug administration (MDA) of azithromycin to pre-school children in Malawi Open
View article: A Portable and Scalable Genomic Analysis Pipeline for<i>Streptococcus pneumoniae</i>Surveillance: GPS Pipeline
A Portable and Scalable Genomic Analysis Pipeline for<i>Streptococcus pneumoniae</i>Surveillance: GPS Pipeline Open
Ever increasing global sequencing capacity provides an unprecedented opportunity in utilising genomic information captured from whole-genome sequencing to enhance pathogen surveillance. However, there is a growing need for developing user-…
View article: Genetic markers associated with host status and clonal expansion of Group B Streptococcus in the Netherlands
Genetic markers associated with host status and clonal expansion of Group B Streptococcus in the Netherlands Open
Objectives Certain Group B Streptococcus (GBS) genotypes are associated with invasive disease in neonates. We conducted a comparative genomic analysis of GBS isolates from neonatal disease and maternal carriage in the Netherlands to determ…