Victoria Fitzpatrick
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View article: Systemic chemokine-modulatory regimen combined with neoadjuvant chemotherapy in patients with triple-negative breast cancer
Systemic chemokine-modulatory regimen combined with neoadjuvant chemotherapy in patients with triple-negative breast cancer Open
Background Higher cytotoxic T lymphocyte (CTL) numbers in the tumor microenvironment (TME) predict pathologic complete response (pCR) to neoadjuvant chemotherapy (NAC) and positive long-term outcomes in triple-negative breast cancer (TNBC)…
View article: 321 Phase I clinical trial assessing the combination of systemic chemokine modulatory regimen targeting TLR3 with neoadjuvant chemotherapy in triple negative breast cancer
321 Phase I clinical trial assessing the combination of systemic chemokine modulatory regimen targeting TLR3 with neoadjuvant chemotherapy in triple negative breast cancer Open
Background Neoadjuvant chemotherapy (NAC) with taxanes is the standard of care in triple negative breast cancer (TNBC). Intratumoral prevalence of CD8+ cytotoxic T-lymphocytes (CTLs) is associated with an improvement in relapse-free surviv…
View article: Seasonal, geographical, and habitat effects on the diet of a recovering predator population: the European pine marten (Martes martes) in Ireland
Seasonal, geographical, and habitat effects on the diet of a recovering predator population: the European pine marten (Martes martes) in Ireland Open
Human activity is increasingly altering the natural world. Yet the natural adaptability of most mammal species remains unknown. Seasonal and spatial influences on the diet of temperate carnivores tending towards omnivory are, particularly,…