Victoria J. Madden
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View article: Informal social support for chronic pain and distress in people with HIV: identifying targets for intervention
Informal social support for chronic pain and distress in people with HIV: identifying targets for intervention Open
Social factors are consequences and determinants of chronic pain, yet little is known about how informal social support operates for people with chronic pain and HIV. The overlapping burdens of emotional distress and chronic pain in people…
View article: Quantifying intra-individual variability in anatomical sites of pain in longitudinal studies
Quantifying intra-individual variability in anatomical sites of pain in longitudinal studies Open
Longitudinal pain studies present an opportunity to understand intra-individual variations in pain. However, current methods to quantify the anatomical extent of pain fail to capture variations across multiple body sites over time. Our aim…
View article: Distress is positively associated with induced secondary hyperalgesia in people with suppressed HIV
Distress is positively associated with induced secondary hyperalgesia in people with suppressed HIV Open
Pain and symptoms of depression and anxiety (here, ‘psychological distress’) are frequently reported by people with HIV. Although pain is widely acknowledged to contribute to distress, distress may also contribute to pain and its persisten…
View article: Provoked cytokine response is not associated with distress or induced secondary hyperalgesia in people with suppressed HIV
Provoked cytokine response is not associated with distress or induced secondary hyperalgesia in people with suppressed HIV Open
Psychological distress predicts the onset and worsening of persistent pain, but the mechanisms that underpin this influence are poorly understood. Pro-inflammatory signalling is a plausible mechanistic link, given its known connections to …
View article: Severe Pain is Associated with Critical Illness and Mortality in Hospitalised Patients Across Africa: A Point Prevalence Study of 22 African Nations
Severe Pain is Associated with Critical Illness and Mortality in Hospitalised Patients Across Africa: A Point Prevalence Study of 22 African Nations Open
View article: The ‘Perioperative Pain Management’ Bundle Improved Outcomes in Patients Undergoing Surgery: A Registry-Based Quality Improvement Study in South Africa
The ‘Perioperative Pain Management’ Bundle Improved Outcomes in Patients Undergoing Surgery: A Registry-Based Quality Improvement Study in South Africa Open
View article: Inflammatory reactivity is unrelated to childhood adversity or provoked modulation of nociception
Inflammatory reactivity is unrelated to childhood adversity or provoked modulation of nociception Open
Adversity in childhood elevates the risk of persistent pain in adulthood. Neuroimmune interactions are a candidate mechanistic link between childhood adversity and persistent pain. We aimed to clarify whether immune reactivity is associate…
View article: The search for clarity, effectiveness and efficiency in physiotherapy care
The search for clarity, effectiveness and efficiency in physiotherapy care Open
View article: The Sensation and Pain Rating Scale: easy to use, clear to interpret, and responsive to clinical change
The Sensation and Pain Rating Scale: easy to use, clear to interpret, and responsive to clinical change Open
Background The Sensation and Pain Rating Scale (SPARS) allows rating of non-painful as well as painful percepts. While it performs well in the experimental context, its clinical utility is untested. This prospective, repeated-measures stud…
View article: The influence of a manipulation of threat on experimentally-induced secondary hyperalgesia
The influence of a manipulation of threat on experimentally-induced secondary hyperalgesia Open
Pain is thought to be influenced by the threat value of the particular context in which it occurs. However, the mechanisms by which a threat achieves this influence on pain are unclear. Here, we explore how threat influences experimentally…
View article: The Global Task Force for Chronic Pain in People with HIV (PWH): Developing a research agenda in an emerging field
The Global Task Force for Chronic Pain in People with HIV (PWH): Developing a research agenda in an emerging field Open
Chronic pain is a common comorbidity in people with HIV (PWH), with prevalence estimates of 25-85%. Research in this area is growing, but significant gaps remain. A Global Task Force of HIV experts was organized to brainstorm a scientific …
View article: Variability in experimental pain studies: nuisance or opportunity?
Variability in experimental pain studies: nuisance or opportunity? Open
View article: The prevalence and risk factors for phantom limb pain in people with amputations: A systematic review and meta-analysis
The prevalence and risk factors for phantom limb pain in people with amputations: A systematic review and meta-analysis Open
This systematic review and meta-analysis estimates that six of every 10 people with an amputation report PLP-a high and important prevalence of PLP. Healthcare professionals ought to be aware of the high rates of PLP and implement strategi…
View article: Chronic Pain in People with HIV: A Common Comorbidity and Threat to Quality of Life
Chronic Pain in People with HIV: A Common Comorbidity and Threat to Quality of Life Open
Evidence indicates that over half of all people with HIV (PWH) will experience nonmalignant chronic pain throughout their lifetimes, with increasing prevalence as they age. Peripheral neuropathy resulting from the neurotoxic effects of HIV…
View article: State of the art: What have the pain sciences brought to physiotherapy?
State of the art: What have the pain sciences brought to physiotherapy? Open
We believe that the pain sciences should be embedded in undergraduate and postgraduate education and training of physiotherapists (including the three key concepts regarding pain) to benefit physiotherapists and their patients.
View article: Barriers to implementing clinical trials on nonpharmacological treatments in developing countries: lessons learnt from addressing pain in HIV
Barriers to implementing clinical trials on nonpharmacological treatments in developing countries: lessons learnt from addressing pain in HIV Open
Pain affects over half of the people living with HIV/AIDS (LWHA), and pharmacological treatment has limited efficacy. Preliminary evidence supports nonpharmacological interventions. We previously piloted a multimodal intervention in amaXho…
View article: The prevalence and risk factors for phantom limb pain in people with amputations: a systematic review and meta-analysis
The prevalence and risk factors for phantom limb pain in people with amputations: a systematic review and meta-analysis Open
Background and objective Phantom limb pain (PLP) is a common complication in people with limb amputations. There are conflicting reports in the literature regarding the prevalence of PLP in people with limb amputations. Therefore, this rev…
View article: A systematic review of experimental methods to manipulate secondary hyperalgesia in humans: protocol
A systematic review of experimental methods to manipulate secondary hyperalgesia in humans: protocol Open
View article: The effectiveness of graded motor imagery for reducing phantom limb pain in amputees: a randomised controlled trial
The effectiveness of graded motor imagery for reducing phantom limb pain in amputees: a randomised controlled trial Open
(PACTR201701001979279).
View article: Shifting beliefs across society would lay the foundation for truly biopsychosocial care
Shifting beliefs across society would lay the foundation for truly biopsychosocial care Open
View article: Modulating pain thresholds through classical conditioning
Modulating pain thresholds through classical conditioning Open
Background Classical conditioning has frequently been shown to be capable of evoking fear of pain and avoidance behavior in the context of chronic pain. However, whether pain itself can be conditioned has rarely been investigated and remai…
View article: Rethinking pain threshold as a zone of uncertainty
Rethinking pain threshold as a zone of uncertainty Open
Background The pain threshold is traditionally conceptualised as a boundary that lies between painful and non-painful events, suggesting a reasonably stable relationship between stimulus and response. In two previous experiments, participa…
View article: Analysis scripts and supplementary files: Barriers to implementing clinical trials on non-pharmacological treatments in developing countries – lessons learnt from addressing pain in HIV
Analysis scripts and supplementary files: Barriers to implementing clinical trials on non-pharmacological treatments in developing countries – lessons learnt from addressing pain in HIV Open
DESCRIPTIONThis repository contains analysis scripts (with outputs), figures from the manuscript, and supplementary files the HIV Pain (HIP) Intervention Study. All analysis scripts (and their outputs -- /outputs subdirectory…
View article: Analysis scripts and supplementary files: Barriers to implementing clinical trials on non-pharmacological treatments in developing countries – lessons learnt from addressing pain in HIV
Analysis scripts and supplementary files: Barriers to implementing clinical trials on non-pharmacological treatments in developing countries – lessons learnt from addressing pain in HIV Open
DESCRIPTIONThis repository contains analysis scripts (with outputs), figures from the manuscript, and supplementary files the HIV Pain (HIP) Intervention Study. All analysis scripts (and their outputs -- /outputs subdirectory…
View article: Analysis scripts and supplementary files: Barriers to implementing clinical trials on non-pharmacological treatments in developing countries – lessons learnt from addressing pain in HIV
Analysis scripts and supplementary files: Barriers to implementing clinical trials on non-pharmacological treatments in developing countries – lessons learnt from addressing pain in HIV Open
DESCRIPTIONThis repository contains analysis scripts (with outputs), figures from the manuscript, and supplementary files the HIV Pain (HIP) Intervention Study. All analysis scripts (and their outputs -- /outputs subdirectory…
View article: Analysis scripts and supplementary files: Barriers to implementing clinical trials on non-pharmacological treatments in developing countries – lessons learnt from addressing pain in HIV
Analysis scripts and supplementary files: Barriers to implementing clinical trials on non-pharmacological treatments in developing countries – lessons learnt from addressing pain in HIV Open
DESCRIPTIONThis repository contains analysis scripts (with outputs), figures from the manuscript, and supplementary files the HIV Pain (HIP) Intervention Study. All analysis scripts (and their outputs -- /outputs subdirectory…
View article: Analysis scripts and supplementary files: Barriers to implementing clinical trials on non-pharmacological treatments in developing countries – lessons learnt from addressing pain in HIV
Analysis scripts and supplementary files: Barriers to implementing clinical trials on non-pharmacological treatments in developing countries – lessons learnt from addressing pain in HIV Open
DESCRIPTIONThis repository contains analysis scripts (with outputs), figures from the manuscript, and supplementary files the HIV Pain (HIP) Intervention Study. All analysis scripts (and their outputs -- /outputs subdirectory…
View article: Analysis scripts and supplementary files: Barriers to implementing clinical trials on non-pharmacological treatments in developing countries – lessons learnt from addressing pain in HIV
Analysis scripts and supplementary files: Barriers to implementing clinical trials on non-pharmacological treatments in developing countries – lessons learnt from addressing pain in HIV Open
DESCRIPTIONThis repository contains analysis scripts (with outputs), figures from the manuscript, and supplementary files the HIV Pain (HIP) Intervention Study. All analysis scripts (and their outputs -- /outputs subdirectory…
View article: Analysis scripts and supplementary files: Was that painful or non-painful? The Sensation and Pain Rating Scale (SPARS) performs well in the experimental context.
Analysis scripts and supplementary files: Was that painful or non-painful? The Sensation and Pain Rating Scale (SPARS) performs well in the experimental context. Open
DESCRIPTIONThis repository contains analysis scripts (with outputs), figures from the manuscript, and supplementary files for two studies on the properties of the Sensation and Pain Rating Scale (SPARS). All analysis scripts …
View article: Supplementary files: Multimodal intervention for pain in HIV/AIDS: depression predicts a remarkably high loss to follow-up
Supplementary files: Multimodal intervention for pain in HIV/AIDS: depression predicts a remarkably high loss to follow-up Open
DESCRIPTIONThis repository contains supplementary files for the HIV Pain Intervention Project (HIP). These files include: - The study protocol () - A description of the four study sites () - The data cleaning and data analysi…