Victoria Lee
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View article: Identifying Genomic Biomarkers of Immunotherapy Response in Advanced NSCLC Using an NLP-Derived Real-World Database
Identifying Genomic Biomarkers of Immunotherapy Response in Advanced NSCLC Using an NLP-Derived Real-World Database Open
View article: Trade-offs between proximity and physical contact during group integration in pigs (<i>Sus scrofa domesticus</i>)
Trade-offs between proximity and physical contact during group integration in pigs (<i>Sus scrofa domesticus</i>) Open
During behavioral trade-offs, individuals have to decide whether to express a behavior which may lead to a reward or potential costs when engaging in a risky situation. Social integration forces animals to make such trade-offs. We hypothes…
View article: Editorial: Using methods and approaches from behavioral ecology to address issues in applied animal sciences
Editorial: Using methods and approaches from behavioral ecology to address issues in applied animal sciences Open
View article: Virus Infection of a Freshwater Cyanobacterium Contributes Significantly to the Release of Toxins Through Cell Lysis
Virus Infection of a Freshwater Cyanobacterium Contributes Significantly to the Release of Toxins Through Cell Lysis Open
Toxic algal-bloom-forming cyanobacteria are a persistent problem globally for many aquatic environments. Their occurrence is attributed to eutrophication and rising temperatures due to climate change. The result of these blooms is often th…
View article: Recurrent adamantinomatous craniopharyngiomas show MAPK pathway activation, clonal evolution and rare TP53-loss-mediated malignant progression
Recurrent adamantinomatous craniopharyngiomas show MAPK pathway activation, clonal evolution and rare TP53-loss-mediated malignant progression Open
View article: EPEN-03. THE MANAGEMENT OF PEDIATRIC AND ADOLESCENT SPINAL EPENDYMOMA; A 20-YEAR NATIONAL EVALUATION INVOLVING UNITED KINGDOM PEDIATRIC ONCOLOGY PRIMARY TREATMENT CENTERS ON BEHALF OF THE UK CHILDREN’S CANCER AND LEUKAEMIA GROUP (CCLG)
EPEN-03. THE MANAGEMENT OF PEDIATRIC AND ADOLESCENT SPINAL EPENDYMOMA; A 20-YEAR NATIONAL EVALUATION INVOLVING UNITED KINGDOM PEDIATRIC ONCOLOGY PRIMARY TREATMENT CENTERS ON BEHALF OF THE UK CHILDREN’S CANCER AND LEUKAEMIA GROUP (CCLG) Open
INTRODUCTION Pediatric spinal ependymomas account for approximately 1% of childhood CNS tumors. Most are myxopapillary ependymomas (MPEs). For symptomatic cases, maximal safe surgical resection is the accepted therapeutic standard. However…
View article: CP-05. MAPK PATHWAY ACTIVATION, CLONAL EVOLUTION, INCLUDING RARE TP53 LOSS, AND THE IMMUNE ENVIRONMENT OF RECURRENT CRANIOPHARYNGIOMA
CP-05. MAPK PATHWAY ACTIVATION, CLONAL EVOLUTION, INCLUDING RARE TP53 LOSS, AND THE IMMUNE ENVIRONMENT OF RECURRENT CRANIOPHARYNGIOMA Open
BACKGROUND Craniopharyngiomas are rare challenging tumours, with around 25% of cases recurring despite surgery and/or radiotherapy. Relatively little is known about the biology of recurrence and there is an urgent need to develop new thera…
View article: Antiviral discovery in toxic cyanobacteria: Low hanging fruit in the age of pandemics
Antiviral discovery in toxic cyanobacteria: Low hanging fruit in the age of pandemics Open
The power of novel vaccination technologies and their rapid development were elucidated clearly during the COVID‐19 pandemic. At the same time, it also became clear that there is an urgent need to discover and manufacture new antivirals th…
View article: Paediatric cerebellar glioblastoma - long-term survival following surgery and adjuvant chemoradiotherapy: A case report and literature review
Paediatric cerebellar glioblastoma - long-term survival following surgery and adjuvant chemoradiotherapy: A case report and literature review Open
Rates of progression-free survival in this rare condition are generally poor, however, several patient and tumour characteristics may infer more favourable prognosis. As increasingly refined means of diagnosis and characterisation are deve…
View article: Effect of insulin insufficiency on ultrastructure and function in skeletal muscle
Effect of insulin insufficiency on ultrastructure and function in skeletal muscle Open
Background Decreased insulin availability and high blood glucose levels, the hallmark features of poorly controlled diabetes, drive disease progression and are associated with decreased skeletal muscle mass. We have shown that mice with β‐…
View article: Nurse-delivered sleep restriction therapy in primary care for adults with insomnia disorder: a mixed-methods process evaluation
Nurse-delivered sleep restriction therapy in primary care for adults with insomnia disorder: a mixed-methods process evaluation Open
Background Sleep restriction therapy (SRT) is a behavioural therapy for insomnia. Aim To conduct a process evaluation of a randomised controlled trial comparing SRT delivered by primary care nurses plus a sleep hygiene booklet with the sle…
View article: Clinical and cost-effectiveness of nurse-delivered sleep restriction therapy for insomnia in primary care (HABIT): a pragmatic, superiority, open-label, randomised controlled trial
Clinical and cost-effectiveness of nurse-delivered sleep restriction therapy for insomnia in primary care (HABIT): a pragmatic, superiority, open-label, randomised controlled trial Open
The National Institute for Health and Care Research Health Technology Assessment Programme.
View article: miR-9 utilizes precursor pathways in adaptation to alcohol in mouse striatal neurons
miR-9 utilizes precursor pathways in adaptation to alcohol in mouse striatal neurons Open
microRNA-9 (miR-9) is one of the most abundant microRNAs in the mammalian brain, essential for its development and normal function. In neurons, it regulates the expression of several key molecules, ranging from ion channels to enzymes, to …
View article: Cost-Effectiveness and Budget Impact of a Novel Antithrombotic Drug Removal System to Reduce Bleeding Risk in Patients on Preoperative Ticagrelor Undergoing Cardiac Surgery
Cost-Effectiveness and Budget Impact of a Novel Antithrombotic Drug Removal System to Reduce Bleeding Risk in Patients on Preoperative Ticagrelor Undergoing Cardiac Surgery Open
View article: The curious case of cyanobacteria: a tale of light and darkness
The curious case of cyanobacteria: a tale of light and darkness Open
Toxic algal bloom-forming cyanobacteria are a persistent problem globally for many aquatic environments. Their occurrence is attributed to eutrophication and rising temperatures due to climate change. The result of these blooms is often lo…
View article: <i>Give My Child a Label</i>: Strategies of Epistemic Corroboration in Case-Building within Child Mental Health Assessments
<i>Give My Child a Label</i>: Strategies of Epistemic Corroboration in Case-Building within Child Mental Health Assessments Open
Child mental health services are in rising demand, but increasingly overstretched and difficult for families to access. This article examines rhetorical techniques used by parents seeking a mental health diagnosis for their child. Using re…
View article: The endogenous repertoire harbors self-reactive CD4+ T cell clones that adopt a follicular helper T cell-like phenotype at steady state
The endogenous repertoire harbors self-reactive CD4+ T cell clones that adopt a follicular helper T cell-like phenotype at steady state Open
View article: Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging
Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging Open
Assessing drug response within live native tissue provides increased fidelity with regards to optimizing efficacy while minimizing off-target effects. Here, using longitudinal intravital imaging of a Rac1-Forster resonance energy transfer …
View article: Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging
Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging Open
Assessing drug response within live native tissue provides increased fidelity with regards to optimizing efficacy while minimizing off-target effects. Here, using longitudinal intravital imaging of a Rac1-Forster resonance energy transfer …
View article: Effect of insulin insufficiency on ultrastructure and function in skeletal muscle
Effect of insulin insufficiency on ultrastructure and function in skeletal muscle Open
Background Decreased insulin availability and high blood glucose levels, the hallmark features of poorly controlled diabetes, drive disease progression and are associated with decreased skeletal muscle mass. We have shown that mice with β-…
View article: Metastatic hepatocellular carcinoma to the sinonasal cavity: A case report and literature review
Metastatic hepatocellular carcinoma to the sinonasal cavity: A case report and literature review Open
Introduction: Persistent unilateral sinonasal symptoms should be concerning for the presence of a sinonasal mass. Metastatic disease should be on the differential during diagnosis. Case presentation: A 76-year-old woman with a history of n…
View article: Nesting jackdaws’ responses to human voices vary with local disturbance levels and the sex of the speaker
Nesting jackdaws’ responses to human voices vary with local disturbance levels and the sex of the speaker Open
Data from an experiment that aimed to determine whether wild jackdaws cue upon the features of approaching voices (accent, familiarity, gender) to guide their responses to a potential threat
View article: Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging
Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging Open
View article: PD01-09 PATIENT PERCEPTION OF OCULAR RISK IN PENTOSAN POLYSULFATE USE FOR INTERSTITIAL CYSTITIS
PD01-09 PATIENT PERCEPTION OF OCULAR RISK IN PENTOSAN POLYSULFATE USE FOR INTERSTITIAL CYSTITIS Open
You have accessJournal of UrologyInfections/Inflammation/Cystic Disease of the Genitourinary Tract: Interstitial Cystitis (PD01)1 Sep 2021PD01-09 PATIENT PERCEPTION OF OCULAR RISK IN PENTOSAN POLYSULFATE USE FOR INTERSTITIAL CYSTITIS Danie…
View article: Online Pronunciation Tutoring for Japanese Learners of English
Online Pronunciation Tutoring for Japanese Learners of English Open
Previous research has shown that pronunciation instruction is facilitative to various aspects of a language learner’s second language (L2) speech development, but intervention was often conducted at a whole-classroom level. This case study…
View article: Assessing the Impact of a Training Initiative for Nasopharyngeal and Oropharyngeal Swabbing for COVID‐19 Testing
Assessing the Impact of a Training Initiative for Nasopharyngeal and Oropharyngeal Swabbing for COVID‐19 Testing Open
Objective The accuracy and reliability of COVID‐19 testing are critical to limit transmission. After observing variability in testing techniques, we otolaryngologists at a tertiary medical center initiated and evaluated the impact of nasop…
View article: Eomes identifies thymic precursors of self-specific memory-phenotype CD8+ T cells
Eomes identifies thymic precursors of self-specific memory-phenotype CD8+ T cells Open
View article: Quantifying resilience to recurrent ecosystem disturbances using flow–kick dynamics
Quantifying resilience to recurrent ecosystem disturbances using flow–kick dynamics Open
View article: Cost-effectiveness of a patient-centred approach to managing multimorbidity in primary care: a pragmatic cluster randomised controlled trial
Cost-effectiveness of a patient-centred approach to managing multimorbidity in primary care: a pragmatic cluster randomised controlled trial Open
Objective Patients with multiple chronic health conditions are often managed in a disjointed fashion in primary care, with annual review clinic appointments offered separately for each condition. This study aimed to determine the cost-effe…
View article: The Role of College and University Endowments
The Role of College and University Endowments Open
This report examines the justification for the tax-exempt status of public and private nonprofit college and university endowments—and the public subsidy that policy involves—and the merits of the arguments for and against modifying this e…