Explanipedia

Effects of Probiotic Short-Term Regiment on Oral Health Parameters in Children: A Pilot Randomized Controlled Trial Open

Edouard Starck, Vanessa Machado, João Botelho, Luís Proença, Helena Barroso , et al. · 2025

Background/Objectives: Streptococcus mutans (S. mutans) is a primary cariogenic bacterium contributing to biofilm acidogenicity and enamel demineralization. Conventional caries prevention relies mainly on mechanical plaque control and diet…

Neutrophils at the Crossroads of Oral Microbiome Dysbiosis and Periodontal Disease Open

João Viana, Tiago Ferro, Vanessa Machado, Naichuan Su, João Botelho · 2025

Neutrophils are the most abundant circulating leukocytes and essential components of innate immunity. Through mechanisms such as phagocytosis, reactive oxygen species (ROS) production, degranulation, and neutrophil extracellular trap (NET)…

OCCLUSAL PLANE LEVELING USING ORTHODONTIC MINI IMPLANTS Open

Mariana Lins da Fonseca Barretto Maia, Vanessa Machado, Ruzielle Maria Silva de Moura, Bruno Alves de Santana, Arthur Barros da Silva , et al. · 2025

A tilted occlusal plane is the cause of an unpleasant smile, but it also represents a challenge due to the complex orthodontic procedures associated with its treatment. Skeletal anchorage allows for effective treatment of this asymmetry in…

Diagnostic Performance of AI-Assisted Software in Sports Dentistry: A Validation Study Open

André Júdice, Diogo Brandão, Carvalho Rodrigues, Cátia Simões, Genilda Meireles Nogueira , et al. · 2025

Artificial Intelligence (AI) applications in sports dentistry have the potential to improve early detection and diagnosis. We aimed to validate the diagnostic performance of AI-assisted software in detecting dental caries, periodontitis, a…

Development and evaluation of a new multidimensional oral health indicator Open

José João Mendes, Rui Santos, Patrícia Lyra, Ana Sintra Delgado, Vanessa Machado , et al. · 2025

Aim To develop a new multidimensional oral health indicator (MOHi) to ascertain and characterize overall oral health status. Materials and Methods MOHi was developed using data from first-time patients ( N = 1,034) attending a university d…

Validation of the Diabetes Risk Assessment in Dentistry Score in <span>NHANES</span> 2009–2014 Open

Carvalho Rodrigues, Vanessa Machado, Luís Proença, José João Mendes, Thomas Kocher , et al. · 2025

Aim To validate the Diabetes Risk Assessment in Dentistry Score (DDS) in a US population–based sample and compare its performance with the American Diabetes Association (ADA) risk calculator and the Leicester Risk Assessment (LRA). Methods…

Evaluating Reporting Completeness in Oral Health Clinical Guidelines: A Meta-Research Study Open

Pierre-Jean Lancry, Patrícia Lyra, José João Mendes, Gustavo G. Nascimento, Vanessa Machado , et al. · 2025

Background: To assess the adherence to clinical practice guidelines (CPGs) reporting guidelines for oral health. Methods: A literature search was carried out in PubMed, Embase and Web of Science from March 2016 to December 2023, selecting …

Comparative assessment of Cochrane’s ROB and ROB2 in dentistry trials: a meta-research study Open

João Viana, Vanessa Machado, Luís Proença, Leandro Chambrone, José João Mendes , et al. · 2025

This meta-research study aimed to compare the assessment of Cochrane's Risk of Bias (RoB) and RoB2 tools in dentistry trials. A sample 150 in vivo randomized clinical trials published between 2020 and 2022 was randomly selected from PubMed…

Elite athletes’ overall oral health, values and related quality of life: a cross-sectional study Open

André Júdice, Daniela Brandão, João Botelho, Vanessa Machado, Luís Proença , et al. · 2025

The present observational study aimed to identify the prevalence of oral health issues in this population and explore the relationship between oral health and factors relevant to athletic performance. One hundred and fourteen elite athlete…

Patient-Reported Outcome Measures in Clinical Practice for Tooth Wear: A Literature Review Open

Inês Argolinha, Sofia Lobo, A.M. Vieira, João Botelho, João Rua , et al. · 2025

Tooth wear is a growing oral health concern with implications for function, esthetics, and psychological well-being, ultimately affecting oral health-related quality of life (OHRQoL). While clinical indices assess tooth wear severity, they…

Combining Self-Reported Information with Radiographic Bone Loss to Screen Periodontitis: A Performance Study Open

José João Mendes, Mônica A.S. Neves, Clara Supiot, Leonor Santiago Pinto, Diogo Tenda , et al. · 2025

Background/Objectives: The objective of this study is to evaluate the diagnostic performance of a combined screening approach using self-reported periodontal information and radiographic periodontal bone loss (R-PBL) in identifying individ…

Antibiotics in periodontal treatment: an umbrella review Open

João Botelho, Patrícia Lyra, Gustavo G. Nascimento, Fábio Renato Manzolli Leite, José João Mendes , et al. · 2025

Aim Antimicrobial stewardship envisions the appropriate use of antimicrobials, including antibiotics. Antibiotic therapy in Periodontology has been widely investigated over the years. This umbrella review aimed to appraise the methodologic…

The Use of Video‐Based Learning to Elucidate the Biological Mechanisms Linking Oral Health With Specific Systemic Medical Conditions Open

Yago Leira, Pilar Batalla, Mariana Morgado, Vanessa Machado, José João Mendes , et al. · 2025

Introduction Video‐based learning has emerged as a powerful tool to overcome the well‐documented limitations of traditional lectures. Hence, the aim of this study was to investigate the impact of the implementation of a video animation on …

Linking peri-implantitis to microbiome changes in affected implants, healthy implants, and saliva: a cross-sectional pilot study Open

Lucinda J. Bessa, Conceição Egas, C. S. S. Pires, Luís Proença, Paulo Mascarenhas , et al. · 2025

Introduction The rising use of dental implants is accompanied by an expected increase in peri-implant diseases, particularly peri-implantitis (PI), which poses a significant threat to implant success and necessitates a thorough understandi…

Assessing Frailty in the Older: The Role of Bite Force as an Independent Indicator Open

Luciano Maia Alves Ferreira, José Brito, Josie Resende Torres da Silva, Marcelo Lourenço da Silva, M. Andrade , et al. · 2025

Background: This study investigates the relationship between bite force and grip strength as indicators of frailty in older adults. Frailty syndrome, characterized by increased vulnerability to adverse health outcomes, poses significant ch…

Advances in Digital Technologies in Dental Medicine: Enhancing Precision in Virtual Articulators Open

Sofia Lobo, Inês Argolinha, Vanessa Machado, João Botelho, João Rua , et al. · 2025

Precision in diagnosis is essential for achieving optimal outcomes in prosthodontics, orthodontics, and orthognathic treatments. Virtual articulators provide a sophisticated digital alternative to conventional methods, integrating intraora…

Sports dentistry intricacies with season-related challenges and the role of athlete-centered outcomes Open

André Júdice, João Botelho, Vanessa Machado, Luís Proença, Luciano Maia Alves Ferreira , et al. · 2025

Sports dentistry is an emerging field focusing on the prevention, treatment, and management of oral health issues in athletes. This review critically examines the current state of sports dentistry, emphasizing the integration of oral healt…

Advances in Digital Technologies in Dental Medicine: Enhancing Precision in Virtual Articulators Open

Sofia Lobo, Inês Argolinha, Vanessa Machado, João Botelho, João Rua , et al. · 2025

Precision in diagnosis is essential for achieving optimal outcomes in prosthodontics, or-thodontics, and orthognathic treatments. Virtual articulators provide a sophisticated digital alternative to conventional methods, integrating intraor…

Exploring AI-Driven Machine Learning Approaches for Optimal Classification of Peri-Implantitis Based on Oral Microbiome Data: A Feasibility Study Open

Ricardo Jorge Pais, João Botelho, Vanessa Machado, Gil Alcoforado, José João Mendes , et al. · 2025

Background: Machine learning (ML) techniques have been recently proposed as a solution for aiding in the prevention and diagnosis of microbiome-related diseases. Here, we applied auto-ML approaches on real-case metagenomic datasets from sa…

Unveiling the Resistome Landscape in Peri-Implant Health and Disease Open

Lucinda J. Bessa, Conceição Egas, João Botelho, Vanessa Machado, Gil Alcoforado , et al. · 2025

Background: The human oral microbiome is a critical reservoir for antibiotic resistance; however, subgingival peri-implant biofilms remain underexplored in this context. We aimed to explore the prevalence and distribution of antibiotic res…

Dental Caries, Tooth Erosion and Nutritional Habits in a Cohort of Athletes: A Cross-Sectional Study Open

Baptiste Mielle, André Júdice, Luís Proença, Vanessa Machado, Ana Margarida Vieira , et al. · 2025

Background/Objectives: this study aimed to study the association of dental caries and erosion in athletes with dietary and oral health habits. Methods: An observational cross-sectional study was conducted at the Sports Dentistry department…

Dental Caries, Tooth Erosion and Nutritional Habits in a Cohort of Athletes: A Cross-Sectional Study Open

Baptiste Mielle, André Júdice, Luís Proença, Vanessa Machado, Ana Margarida Vieira , et al. · 2025

To study the association of dental caries and erosion in athletes with dietary and oral health habits. An observational cross-sectional study was conducted at the Sports Dentistry department of a university clinic. Intraoral examination in…

Exploring AI-Driven Machine Learning Approaches for Optimal Classification of Peri-Implantitis Based on Oral Microbiome Data: A Feasibility Study Open

Ricardo Jorge Pais, João Botelho, Vanessa Machado, Gil Alcoforado, José João Mendes , et al. · 2025

Background: Machine-learning (ML) techniques have been recently proposed as a solution for aiding in the prevention and diagnosis of microbiome-related diseases. Here, we applied auto-ML approaches on real-case metagenomic datasets from sa…

Comparative Assessment of Cochrane’s ROB and ROB2 in Dentistry Trials: A Meta-Research Study Open

João Viana, Vanessa Machado, Luís Proença, Leandro Chambrone, João Botelho · 2025

This meta-research study aimed to compare the assessment of Cochrane's Risk of Bias (RoB) and RoB2 tools in dentistry trials. A sample 150 in vivo randomized clinical trials published between 2020 and 2022 was randomly selected from P…

Evaluation of Oral hygiene Awareness and health-promoting behaviors Among Adults in the Masovian Region of Poland: A Cross-Sectional Survey Study Open

Vanessa Machado, Soraia Rodrigues, Giancarlo De la Torre Canales, Ana Sintra Delgado · 2025

No Robust Evidence to Support the Use of Antibiotics for Periodontal Management: An Umbrella Review Open

João Botelho, Patrícia Lyra, Gustavo G. Nascimento, Fábio Renato Manzolli Leite, José João Mendes , et al. · 2025

Ethical Challenges in End-of-Life Care for Individuals with Severe and Persistent Mental Illness: A Qualitative Study Open

Vanessa Machado, Carlos Laranjeira, Ana Sintra Delgado, María Pía Ferraz, Ana Botelho · 2025

Unveiling the Resistome Landscape in Peri-Implant Health and Disease Open

Lucinda J. Bessa, Conceição Egas, João Botelho, Vanessa Machado, Gil Alcoforado , et al. · 2024

Background: The human oral microbiome is a critical reservoir for antibiotic resistance, however, subgingival peri-implant biofilms remain underexplored in this context. We aimed to explore the prevalence and distribution of antibiotic res…

Video-based approaches in health education: a systematic review and meta-analysis Open

Mariana Morgado, João Botelho, Vanessa Machado, José João Mendes, Olusola Adesope , et al. · 2024

This study evaluates the impact of video-based approaches on health education. PUBMED, Web of Science, EMBASE, CENTRAL, and LILACS databases were searched from their inception until November 2022. Randomised controlled trials (RCTs) and no…

Perceived Infant Discomfort Linked to Lower Maternal Oral Health Quality of Life: Results from a Cross-Sectional Study Open

Lisetty Garrido, Inês Rodrigues, Patrícia Lyra, Luís Proença, João Botelho , et al. · 2024

Aim: We aimed to explore whether there is an association between maternal perceived infant discomfort due to suggestive gastrointestinal alterations and oral-health-related quality of life (OHRQoL) through a survey. Materials and Methods: …

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