Vignesh Sakthivelu
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View article: Publisher Correction: Functional synapses between neurons and small cell lung cancer
Publisher Correction: Functional synapses between neurons and small cell lung cancer Open
View article: Functional synapses between neurons and small cell lung cancer
Functional synapses between neurons and small cell lung cancer Open
Small cell lung cancer (SCLC) is a highly aggressive type of lung cancer, characterized by rapid proliferation, early metastatic spread, frequent early relapse and a high mortality rate 1–3 . Recent evidence has suggested that innervation …
View article: Functional synapses between small cell lung cancer and glutamatergic neurons
Functional synapses between small cell lung cancer and glutamatergic neurons Open
Small cell lung cancer (SCLC) is a highly aggressive type of lung cancer, characterized by rapid proliferation, early metastatic spread, clinical recurrence and high rate of mortality. Using in vivo insertional mutagenesis screening in con…
View article: Metabolic control of adult neural stem cell self-renewal by the mitochondrial protease YME1L
Metabolic control of adult neural stem cell self-renewal by the mitochondrial protease YME1L Open
The transition between quiescence and activation in neural stem and progenitor cells (NSPCs) is coupled with reversible changes in energy metabolism with key implications for lifelong NSPC self-renewal and neurogenesis. How this metabolic …
View article: Metabolic control of adult neural stem cell self-renewal by the mitochondrial proteaseYME1L
Metabolic control of adult neural stem cell self-renewal by the mitochondrial proteaseYME1L Open
The transition between quiescence and activation in neural stem and progenitor cells (NSPCs) is coupled to reversible changes in energy metabolism with key implications for life-long NSPC self-renewal and neurogenesis. How this metabolic p…
View article: Metabolic control of adult neural stem cell self-renewal by the mitochondrial protease YME1L
Metabolic control of adult neural stem cell self-renewal by the mitochondrial protease YME1L Open
The transition between quiescence and activation in neural stem and progenitor cells (NSPCs) is coupled to reversible changes in energy metabolism with key implications for life-long NSPC self-renewal and neurogenesis. How this metabolic p…
View article: Neuronal metabolic rewiring promotes resilience to neurodegeneration caused by mitochondrial dysfunction
Neuronal metabolic rewiring promotes resilience to neurodegeneration caused by mitochondrial dysfunction Open
Proteomic analysis of dysfunctional neurons reveals a metabolic program that is activated to counteract neurodegeneration.
View article: Mitochondria-Endoplasmic Reticulum Contacts in Reactive Astrocytes Promote Vascular Remodeling
Mitochondria-Endoplasmic Reticulum Contacts in Reactive Astrocytes Promote Vascular Remodeling Open
View article: Substitutions of PrP N-terminal histidine residues modulate scrapie disease pathogenesis and incubation time in transgenic mice
Substitutions of PrP N-terminal histidine residues modulate scrapie disease pathogenesis and incubation time in transgenic mice Open
Prion diseases have been linked to impaired copper homeostasis and copper induced-oxidative damage to the brain. Divalent metal ions, such as Cu2+ and Zn2+, bind to cellular prion protein (PrPC) at octapeptide repeat (OR) and non-OR sites …