Explanipedia

Retinal optical coherence tomography angiography imaging in population studies Open

Amir H. Kashani, Tos T. J. M. Berendschot, Sophie Bonnin, Lucia Sobrin, Danilo Andrade De Jesus , et al. · 2025

Background Widespread use of retinal optical coherence tomography angiography (OCT-A) imaging in population-based studies requires methodological and analytical consensus to ensure reproducible and accurate results. Objective Development o…

Lens subluxation in retinoblastoma – Where does it fit in the classification of retinoblastoma Open

Vikas Khetan, Subramanian Krishnakumar, Puja Maitra · 2024

Retinoblastoma – A comprehensive review, update and recent advances Open

Adwaita Nag, Vikas Khetan · 2024

Retinoblastoma is the most common pediatric ocular malignancy. It is triggered by a biallelic mutation in the RB1 gene or MYCN oncogene amplification. Retinoblastomas can be unilateral (60%–70%) or bilateral (30%–40%); bilateral tumors are…

Masquerade syndrome: A review of uveitic imposters Open

Parthopratim Dutta Majumder, Vikas Khetan, Jyotirmay Biswas · 2024

Masquerade syndromes in uveitis are complex clinical conditions where non-inflammatory diseases mimic uveitic manifestations, often leading to diagnostic and therapeutic challenges. This review delves into the diverse spectrum of masquerad…

Retinoblastoma in Asia Open

Swathi Kaliki, Vijitha S. Vempuluru, Ashik Mohamed, Mazin Faisal Al‐Jadiry, Richard Bowman , et al. · 2023

The author(s) have no proprietary or commercial interest in any materials discussed in this article.

Next-generation sequencing-based genetic testing and phenotype correlation in retinitis pigmentosa patients from India Open

Parveen Sen, Natarajan N. Srikrupa, Puja Maitra, Srilekha Sundaramurthy, P. Porkodi , et al. · 2023

Purpose: Inherited retinal dystrophies (IRD) are a heterogeneous group of retinal diseases leading to progressive loss of photoreceptors through apoptosis. Retinitis pigmentosa (RP) is considered the most common form of IRD. Panel-based te…

Look into their eyes and save their vision: role of primary health care provider in early diagnosis of retinoblastoma Open

Soundharyaa Gunaseelan, Pujitha, M.S. Latha, Julius Xavier Scott, Vikas Khetan · 2023

Childhood cancer is not amenable to preventive or screening strategies. The most effective strategy to reduce the cancer burden and improve outcomes, is to focus on early, correct diagnosis followed by evidence-based therapy. When diagnose…

Genetic testing Open

Diego I. Paredes, Lorena Haefeli, Onochie Okoye, Jenina Capasso, Celeste S. Wyman , et al. · 2023

Reply Open

Paul T. Finger, Ankit Singh Tomar, Brenda Gallie, Tero Kivelä, Ashwin Mallipatna , et al. · 2022

Understanding the mechano and chemo response of retinoblastoma tumor cells Open

Divya Gopal, Ramani Madhura, Vikas Khetan, Pukhraj Rishi, Narayanan Janakiraman · 2022

Younger Age and Albuminuria are Associated with Proliferative Diabetic Retinopathy and Diabetic Macular Edema in the South Indian GeNetics of DiAbeTic Retinopathy (SIGNATR) Study Open

Gayatri Susarla, Alessandra Rizza, Ashley Li, Samuel Han, Rehana Khan , et al. · 2022

Purpose: The purpose of the South Indian GeNetics of DiAbeTic Retinopathy (SIGNATR) Study is to identify non-genetic and genetic risk factors associated with diabetic retinopathy (DR). This report examines the non-genetic ris…

Retinoblastoma tumour cells in central retinal vessels Open

Vikas Khetan, Sashwanthi Mohan, Subramanian Krishnakumar · 2022

The left eye of an 11-year-old girl had iris neovascularization, neovascular glaucoma, and a retrolental exudative retinal detachment with a suspicious mass lesion in the fundus. A calcified lesion in the superonasal quadrant with closed f…

Challenges in the Management of Retinoblastoma during Nationwide Lockdown: An Observational Study from a Retinoblastoma Center in South India Open

Janani Arul, Suganeswari Ganesan, Vikas Khetan, Latha M. Sneha, Dhaarani Jayaraman , et al. · 2022

Introduction The nationwide lockdown due to coronavirus disease 2019 led to travel restrictions resulting in a delay in diagnosis, treatment, and follow-up of children with retinoblastoma (RB). Objectives We audited the impact and challeng…

Circumscribed choroidal hemangioma in a case of neurofibromatosis type 1 Open

Harshit Vaidya, Vikas Khetan · 2022

A case of non-Hodgkin lymphoma diagnosed after 35-month of initial presentation as recurrent vitritis with multiple negative biopsies Open

Parthopratim Dutta Majumder, Mayur Moreker, Satish V. Khadilkar, Bharat Bhosale, Vikas Khetan · 2022

To report a case of non-Hodgkin lymphoma (NHL) that was diagnosed 35-month of initial ocular manifestation. Retrospective chart review. A 53-year-old male presented with painless diminution of vision in both eyes. He subsequently underwent…

Metastatic Death Based on Presenting Features and Treatment for Advanced Intraocular Retinoblastoma Open

Ankit Singh Tomar, Paul T. Finger, Brenda L. Gallie, Tero Kivelä, Ashwin Mallipatna , et al. · 2022

The AJCC-RB cT2 and cT3 subcategories and size-based AJCC-OOTF Groups 3 (> 2/3 globe volume) and 4 (diffuse infiltrating RB) provided a robust stratification of clinical risk for metastatic death in advanced intraocular RB. Primary enuclea…

High-risk Pathologic Features Based on Presenting Findings in Advanced Intraocular Retinoblastoma Open

Ankit Singh Tomar, Paul T. Finger, Brenda Gallie, Tero Kivelä, Ashwin Mallipatna , et al. · 2022

Younger Age and Albuminuria are Associated with Proliferative Diabetic Retinopathy and Diabetic Macular Edema in the South Indian GeNetics of DiAbeTic Retinopathy (SIGNATR) Study Open

Gayatri Susarla, Alessandra Rizza, Ashley Li, Samuel Han, Rehana Khan , et al. · 2022

Purpose: The purpose of the South Indian GeNetics of DiAbeTic Retinopathy (SIGNATR) Study is to identify non-genetic and genetic risk factors associated with diabetic retinopathy (DR). This report examines the non-genetic ris…

Comparison Between Ranibizumab Biosimilar, Innovator Ranibizumab and Bevacizumab in a Real-World Situation Open

Dhanashree Ratra, Krishnakanta Roy, Sneha Giridhar, Sushant Madaan, Pramod Bhende , et al. · 2021

Chronic myelogenous leukemia in a child following treatment for bilateral retinoblastoma Open

Haitham Hilal Al-Mahrouqi, Anuradha Ganesh, Abdulhakim Al‐Rawas, Vikas Khetan, Sana Al‐Zuhaibi · 2021

A 3-year-old child was incidentally found to have chronic myelogenous leukemia (CML) during an admission for a routine ophthalmic examination under anesthesia. The child had received systemic chemotherapy and focal treatment for Groups C a…

Retinoblastoma seeds: impact on American Joint Committee on Cancer clinical staging Open

Ankit Singh Tomar, Paul T. Finger, Brenda Gallie, Tero Kivelä, Ashwin Mallipatna , et al. · 2021

Aim To investigate whether the American Joint Committee on Cancer (AJCC) clinical category cT2b needs to be subclassified by the type and distribution of retinoblastoma (RB) seeding. Methods Multicentre, international registry-based data w…

Sex, gender, and retinoblastoma: analysis of 4351 patients from 153 countries Open

Ido Didi Fabian, Vikas Khetan, Andrew W. Stacey, Allen Foster, Dupe Ademola-Popoola , et al. · 2021

Risk factors for optical coherence tomography-assessed center-involving diabetic macular edema in a South Indian population Open

Samuel Han, Alessandra Rizza, Rehana Khan, Ashley Li, Weilin Chan , et al. · 2021

Involvement of lens in Retinoblastoma (RB)- Challenging the concept of lens immunity and proposal for lens features to be defined in classification systems Open

Vikas Khetan, Puja Maitra · 2021

Invariant Differential Expression Analysis Reveals Mechanism of Cancer Resistance to Cell Cycle Inhibitors Open

Amit Chatterjee, Sonalisa Pandey, Ravikanth Danda, R. Ranjith Kumar, S. Maheswari , et al. · 2021

Retinoblastoma (RB) is a good model to study drug resistance to cell-cycle inhibitors because it is driven by mutations in the core components of cell-cycle, i.e, Rb gene. However, there is limited gene expression dataset in RB which has m…

Infiltration of optic nerve head in acute lymphoblastic leukaemia presenting as an initial isolated site of relapse Open

Harshit Vaidya, Vikas Khetan · 2021

A 10-year-old male, known case of acute lymphoblastic leukemia for 3 years, presented with a 1-day history of sudden onset painless diminution of vision in the left eye. He was on maintenance therapy with intravenous methotrexate and vincr…

Chromosomal Microarray in Isolated Congenital and Developmental Cataract Open

Thales A. C. de Guimarães, Jenina E. Capasso, Nicholas R. Bello, Nutsuchar Wangtiraumnuay, Michelle D. Lingao , et al. · 2021

Introduction: The etiologies of congenital and developmental cataracts are diverse. Most are not syndromic and have no identifiable cause, thus creating a diagnostic dilemma. We investigated the utility of chromosomal microarray in identif…

Correction to: EpCAM aptamer mediated cancer cell specific delivery of EpCAM siRNA using polymeric nanocomplex Open

Nithya Subramanian, Jagat R. Kanwar, Prasanna kumar Athalya, Narayanan Janakiraman, Vikas Khetan , et al. · 2020

An amendment to this paper has been published and can be accessed via the original article.

Global Retinoblastoma Treatment Outcomes Open

Ankit Singh Tomar, Paul T. Finger, Brenda Gallie, Tero Kivelä, Ashwin Mallipatna , et al. · 2020

This international, multicenter, registry-based analysis of retinoblastoma management revealed that lower national income levels were associated with significantly higher rates of metastasis-related mortality, local treatment failure, and …

Retinoblastoma management during the COVID‐19 pandemic: A report by the Global Retinoblastoma Study Group including 194 centers from 94 countries Open

Ido Didi Fabian, Andrew W. Stacey, Richard Bowman, Vikas Khetan, Sharon Blum , et al. · 2020

We declare no competing interests relevant to the present work. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) …

Vikas Khetan YOU? Author Swipe