Vikram Gharge
YOU?
Author Swipe
Advancements in stability assessment: a novel method for impurity profiling in Montelukast and Fexofenadine dosage forms by RP-HPLC Open
This study aims to develop and validate a specific, precise, and robust RP-HPLC method for the impurity profiling of Montelukast sodium and Fexofenadine in their combined tablet formulation. The method ensures accurate detection and quanti…
Assessment and Computational Estimation of Omeprazole and Levosulpiride Impurities in Fixed Dose Combination by AQbD Approach Open
This study focuses on novel high-performance liquid chromatography (HPLC) method to simultaneously identify and quantify degradation products of esomeprazole and levosulpiride in capsule dosage form, enhancing analytical precision and reli…
Development of Paracetamol, Chlorpheniramine Maleate & Phenylephrine Hydrochloride syrup for Pediatric use & evaluation by applying QbD Approach to analytical RP-HPLC method Open
The present work is based on formulation & analytical method development of Paracetamol (PCM), Chlorpheniramine Maleate (CPM) & Phenylephrine Hydrochloride (PPH) syrup. A Fixed dose combination (FDC) of PCM, PPH & CPM are commonly used in …
Stability Indicating RP-HPLC Method for the Estimation of Impurities in Esomeprazole Gastro-Resistant Tablets by AQbD Approach Open
Background: Esomeprazole (ESO) gastro-resistant tablets (40 mg) are sold under the brand name, Zosa, which effectively manages conditions associated with the overproduction of gastric acid, including peptic ulcer disease and Zollinger-Elli…
Multivariate Analysis and Computational Predictability of Modified Release Formulation of Chirally Pure Metoprolol Succinate Open
This study employs computational techniques to predict the performance of a modified-release matrix formulation of chirally pure S (-) metoprolol succinate, using a Quality by Design (QbD) approach. The research defines the Quality Target …
Techniques for Dissolution and Bioavailability Enhancement of Poorly Water-Soluble Drugs Open
Solubility, the phenomenon of dissolution of solute in solvent to give a homogenous system, is one of the important parameters to achieve desired concentration of drug in systemic circulation for desired pharmacological response. Low aqueo…
Development and Evaluation of Ondansetron Orally Disintegrating Tablets Open
Orally disintegrating tablet (ODT) has number of advantages like faster onset of action, ease of administration, rapid disintegration and dissolution etc. A novel attempt has been made to develop orally disintegrating tablets of Ondansetro…