Vikrant Parihar
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View article: Bismuth Quadruple Therapy with Doxycycline Is an Effective First-Line Therapy for Helicobacter pylori in an Irish Cohort
Bismuth Quadruple Therapy with Doxycycline Is an Effective First-Line Therapy for Helicobacter pylori in an Irish Cohort Open
Background: There has been a reduction in successful H. pylori eradication rates recently, which is largely attributed to increasing antibiotic resistance. In areas of high dual clarithromycin and metronidazole resistance such as ours, Maa…
View article: P1139 A real-world, observational study comparing the side effects of budesonide MMX with prednisolone and the resolution of symptoms in patients with mild to moderate ulcerative colitis
P1139 A real-world, observational study comparing the side effects of budesonide MMX with prednisolone and the resolution of symptoms in patients with mild to moderate ulcerative colitis Open
Background Budesonide MMX is indicated for the induction of remission in mild to moderate Ulcerative Colitis (UC) patients when 5-ASA treatment is not sufficient. There is limited real-world evidence of the relative side effects following …
View article: The second Irish Helicobacter pylori Working Group consensus for the diagnosis and treatment of Helicobacter pylori infection in adult patients in Ireland
The second Irish Helicobacter pylori Working Group consensus for the diagnosis and treatment of Helicobacter pylori infection in adult patients in Ireland Open
Background There has been an increase in resistance to many of the antimicrobials used to treat Helicobacter pylori ( H. pylori ) nationally and internationally. Primary clarithromycin resistance and dual clarithromycin and metronidazole r…
View article: Screening for undiagnosed pancreatic exocrine insufficiency (PEI) in a cohort of diabetic patients using faecal elastase testing and PEI scoring system
Screening for undiagnosed pancreatic exocrine insufficiency (PEI) in a cohort of diabetic patients using faecal elastase testing and PEI scoring system Open
Introduction Type 1 and type 2 diabetes mellitus (DM) are often accompanied by mild forms of pancreatic exocrine insufficiency (PEI). The prevalence rates of PEI in diabetic patients are unclear and variable depending on the testing modali…
View article: Mature tertiary lymphoid structures in lung adenocarcinoma are associated with better progression free survival
Mature tertiary lymphoid structures in lung adenocarcinoma are associated with better progression free survival Open
Introduction/Objective The presence of inducible lymphoid structures known as tertiary lymphoid structures in the tumor microenvironment has been shown to correlate with positive clinical outcome. However, the maturation states of lymphoid…
View article: A Case of Colonic Ischaemia Masquerading as a Colonic Mass
A Case of Colonic Ischaemia Masquerading as a Colonic Mass Open
Intestinal ischaemia is an uncommon vascular syndrome resulting from an acute or chronic drop in blood supply to the bowel, with varied clinical presentations. Intestinal ischaemia can present similarly to other conditions, leaving the cli…
View article: P597 Effectiveness and safety of vedolizumab therapy in an ulcerative colitis cohort with significant prior anti-TNF exposure
P597 Effectiveness and safety of vedolizumab therapy in an ulcerative colitis cohort with significant prior anti-TNF exposure Open
Vedolizumab (VDZ) is a monoclonal antibody designed to inhibit α4β7 integrin and result in gut-selective anti-inflammatory activity. Randomised control trials have shown VDZ to be safe and effective in treating patients with ulcerative col…
View article: Adherence to European Polypectomy Guidelines: Retrospective Experience from a Tertiary Irish Hospital
Adherence to European Polypectomy Guidelines: Retrospective Experience from a Tertiary Irish Hospital Open
Background and Study Aim: The European guidelines for colorectal cancer screening state that snare resection should remove any polyps ≥5 mm. This study aimed to investigate if these new guidelines are adhered to in clinical practice. Patie…
View article: A Tale of Two Lymphomas
A Tale of Two Lymphomas Open
We present a patient with coeliac disease who developed refractory coeliac disease II, which was complicated by the development of metachronous lymphomas.
View article: 24 Measuring the value of endoscopic retrograde cholangiopancreatography (ERCP) activity: an opportunity to stratify endoscopists based on their value
24 Measuring the value of endoscopic retrograde cholangiopancreatography (ERCP) activity: an opportunity to stratify endoscopists based on their value Open
Background The value in healthcare can be defined as patient health outcomes achieved per monetary unit spent. Aim To characterise the value of ERCP performance of four gastroenterologists. Method Medical records of patients undergoin…
View article: 44 Conscious sedation in ERCP : the uncomfortable truth
44 Conscious sedation in ERCP : the uncomfortable truth Open
Background Compared with standard endoscopy, Endoscopic Retrograde Cholangio-Pancreatography(ERCP) is an uncomfortable, complex procedure that typically requires higher doses of sedative and analgesic medication. Our unit, like many throu…
View article: P403 Golimumab therapy for ulcerative colitis – an Irish multicentre experience
P403 Golimumab therapy for ulcerative colitis – an Irish multicentre experience Open
Background: Golimumab (GLB) is a subcutaneous anti-tumour necrosis factor alpha (anti-TNF) therapy. Randomised controlled trials have demonstrated GLB efficacy in the induction and maintenance of remission in ulcerative colitis (UC). Data …
View article: P380 Assessment of the awareness and education of vaccination in our IBD cohort: an observational study
P380 Assessment of the awareness and education of vaccination in our IBD cohort: an observational study Open
Background: Inflammatory Bowel Disease (IBD) confers an increased risk of opportunistic infection. Chronic inflammation and the use of steroids, thiopurines and biologic medications contribute to immunosuppression state. Ecco guidelines re…
View article: CMV pneumonitis in an immunosuppressed Crohn's disease patient
CMV pneumonitis in an immunosuppressed Crohn's disease patient Open
Learning point for clinicians
We recommend Inflammatory Bowel Disease patients should have full viral serology testing prior to commencing immunosuppressive agents. While vaccinations are not available for all viruses, it highlights at-ri…