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View article: NCOG-11. Factors influencing social competence in adolescents and young adults surviving pediatric brain tumors treated with radiation therapy: A scoping review
NCOG-11. Factors influencing social competence in adolescents and young adults surviving pediatric brain tumors treated with radiation therapy: A scoping review Open
Pediatric brain tumors (PBTs) are among the most prevalent childhood cancers, with survivors often experiencing significant cognitive and social challenges, particularly those who undergo cranial irradiation. Despite increasing use of cogn…
View article: Eastern Canadian Gastrointestinal Cancer Consensus Conference 2024
Eastern Canadian Gastrointestinal Cancer Consensus Conference 2024 Open
The Eastern Canadian Gastrointestinal Cancer Consensus Conference was an annual meeting that was held in St. John’s, Newfoundland and Labrador, from 26 to 28 September 2024. This included experts in medical oncology, radiation oncology, su…
View article: Brain Metastases in Gynaecologic Cancer: A Retrospective Cohort Study Evaluating Treatment Outcomes, Prognostic Factors, and Overall Survival
Brain Metastases in Gynaecologic Cancer: A Retrospective Cohort Study Evaluating Treatment Outcomes, Prognostic Factors, and Overall Survival Open
(1) Background: The objectives of this study were to assess survival of patients with a diagnosis of brain metastases secondary to gynaecologic malignancy and the impact of clinicopathological factors on prognosis in this population. (2) M…
View article: BIOM-40. THERABIOME-GBM: THERAPEUTIC OUTCOMES RELATED TO GUT MICROBIOME IN GLIOBLASTOMA (GBM) PATIENTS RECEIVING CHEMO-RADIATION: A PROSPECTIVE OBSERVATIONAL STUDY
BIOM-40. THERABIOME-GBM: THERAPEUTIC OUTCOMES RELATED TO GUT MICROBIOME IN GLIOBLASTOMA (GBM) PATIENTS RECEIVING CHEMO-RADIATION: A PROSPECTIVE OBSERVATIONAL STUDY Open
PURPOSE A major barrier to improving outcomes in glioblastoma multiforme (GBM) is overcoming a heavily immunosuppressed tumor and systemic environment, as demonstrated by several negative phase III randomized studies of nivolumab in both n…
View article: RBIO-10. NEUROMODULATORY EFFECT AND DOSE RESPONSE OF FUNCTIONAL RADIOSURGERY ON CORTICAL NEURONS
RBIO-10. NEUROMODULATORY EFFECT AND DOSE RESPONSE OF FUNCTIONAL RADIOSURGERY ON CORTICAL NEURONS Open
PURPOSE The effects of functional radiosurgery on neuronal circuits remain poorly understood. Neurons of the prefrontal cortex communicate via precisely-timed action potentials that control cognition. Here, we examined the dose response of…
View article: Eastern Canadian Gastrointestinal Cancer Consensus Conference 2023
Eastern Canadian Gastrointestinal Cancer Consensus Conference 2023 Open
The annual Eastern Canadian Gastrointestinal Cancer Consensus Conference 2023 was held in Quebec City, Quebec 2–4 February 2023. The purpose of the conference was to develop consensus statements on emerging and evolving treatment paradigms…
View article: Cranial Radiation Therapy as Salvage in the Treatment of Relapsed Primary CNS Lymphoma
Cranial Radiation Therapy as Salvage in the Treatment of Relapsed Primary CNS Lymphoma Open
Primary central nervous system lymphoma (PCNSL) is a rare malignancy. Standard of care is upfront high-dose methotrexate (HD-MTX) chemotherapy, while cranial radiation is more commonly used in the salvage setting. In this retrospective stu…
View article: Diagnostic Accuracy of Centrally Restricted Diffusion Sign in Cerebral Metastatic Disease: Differentiating Radiation Necrosis from Tumor Recurrence
Diagnostic Accuracy of Centrally Restricted Diffusion Sign in Cerebral Metastatic Disease: Differentiating Radiation Necrosis from Tumor Recurrence Open
Purpose: The centrally restricted diffusion sign of diffusion-weighted imaging (DWI) is associated with radiation necrosis (RN) in treated gliomas. Our goal was to evaluate its diagnostic accuracy to distinguish RN from tumor recurrence (T…
View article: A longitudinal analysis of early lung function trajectory in survivors of childhood Hodgkin lymphoma
A longitudinal analysis of early lung function trajectory in survivors of childhood Hodgkin lymphoma Open
Background Childhood Hodgkin lymphoma survivors suffer from long‐term effects decades after treatment completion with a prevalence of pulmonary dysfunction of up to 65.2%. Aims This study explored the early trajectory of pulmonary function…
View article: P.130 Clinical prognostic factors in adult intracranial ependymoma patients – A fifty year multi-institutional experience
P.130 Clinical prognostic factors in adult intracranial ependymoma patients – A fifty year multi-institutional experience Open
Background: Standard of care treatment for adult intracranial ependymoma patients includes maximal safe surgical resection, while the role for adjuvant radiotherapy remains unclear with existing data from small retrospective series’. Accor…
View article: Eastern Canadian Gastrointestinal Cancer Consensus Conference 2019
Eastern Canadian Gastrointestinal Cancer Consensus Conference 2019 Open
The annual Eastern Canadian Gastrointestinal Cancer Consensus Conference 2019 was held in Morell, Prince Edward Island, 19–21 September 2019. Experts in medical oncology, radiation oncology, and surgical oncology who are involved in the ma…
View article: Trajectory of Lung Function Change in Childhood Cancer Survivors: An Exploratory Analysis
Trajectory of Lung Function Change in Childhood Cancer Survivors: An Exploratory Analysis Open
Introduction Although five-year survival rates for childhood cancer have surpassed 85%, childhood cancer survivors continue to suffer from long-term effects decades after treatment completion. The prevalence of pulmonary dysfunction is ver…
View article: Hypofractionated radiotherapy for elderly breast cancer patients: from early stages disease to local palliation for unresectable disease
Hypofractionated radiotherapy for elderly breast cancer patients: from early stages disease to local palliation for unresectable disease Open
There is a lack of clear guidelines on optimal radiotherapy dose regimen for elderly breast cancer patients. This review summarizes the current evidence on role of hypofractionated radiotherapy in elderly breast cancer. Also, suggestions h…