Anne-Hélène Clair
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View article: Prospective Acceptability of Digital Therapy for Major Depressive Disorder in France: Multicentric Real-Life Study
Prospective Acceptability of Digital Therapy for Major Depressive Disorder in France: Multicentric Real-Life Study Open
Background Major depressive disorder is one of the leading causes of disability worldwide. Although most international guidelines recommend psychological and psychosocial interventions as first-line treatment for mild to moderate depressio…
View article: Prospective Acceptability of Digital Therapy for Major Depressive Disorder in France: Multicentric Real-Life Study (Preprint)
Prospective Acceptability of Digital Therapy for Major Depressive Disorder in France: Multicentric Real-Life Study (Preprint) Open
BACKGROUND Major depressive disorder is one of the leading causes of disability worldwide. Although most international guidelines recommend psychological and psychosocial interventions as first-line treatment for mild to moderate depressi…
View article: Deprexis® Acceptability study in REal life (DARE): study design
Deprexis® Acceptability study in REal life (DARE): study design Open
Introduction Depression is a leading cause of disability, worldwide. Recently, WHO highlighted the negative impact of recent crises (COVID-19 pandemic, war in Ukraine, economic crisis). Although most international guidelines recommend psyc…
View article: Therapies for obsessive-compulsive disorder: Current state of the art and perspectives for approaching treatment-resistant patients
Therapies for obsessive-compulsive disorder: Current state of the art and perspectives for approaching treatment-resistant patients Open
Even though obsessive compulsive disorder (OCD) is one of the ten most disabling diseases according to the WHO, only 30–40% of patients suffering from OCD seek specialized treatment. The currently available psychotherapeutic and pharmacolo…
View article: Understanding the potential of digital therapies in implementing the standard of care for depression in Europe
Understanding the potential of digital therapies in implementing the standard of care for depression in Europe Open
Depressive disorders represent the largest proportion of mental illnesses, and by 2030, they are expected to be the first cause of disability-adjusted life years [1]. The COVID-19 pandemic exacerbated prevalence and burden of depression an…
View article: Deep Brain Stimulation for Refractory Obsessive-Compulsive Disorder: Towards an Individualized Approach
Deep Brain Stimulation for Refractory Obsessive-Compulsive Disorder: Towards an Individualized Approach Open
Obsessive-compulsive disorder (OCD) is a neuropsychiatric disorder featuring repetitive intrusive thoughts and behaviors associated with a significant handicap. Of patients, 20% are refractory to medication and cognitive behavioral therapy…
View article: Recent advances in deep brain stimulation in psychiatric disorders
Recent advances in deep brain stimulation in psychiatric disorders Open
Deep brain stimulation (DBS) has been offered to patients suffering of severe and resistant neuropsychiatric disorders like Obsessive Compulsive Disorder (OCD), Gilles de la Tourette Syndrome (TS) and Major Depression (MDD). Modulation of …
View article: Altered anatomical connections of associative and limbic cortico-basal-ganglia circuits in obsessive-compulsive disorder
Altered anatomical connections of associative and limbic cortico-basal-ganglia circuits in obsessive-compulsive disorder Open
Background: Current neurocognitive models suppose dysfunctions of associative and limbic cortico-basal ganglia circuits to be at the core of obsessive-compulsive disorder (OCD). As little is known about the state of underlying anatomical c…