Vincent Émond
YOU?
Author Swipe
View article: Serum placental growth factor as a biomarker of cerebrovascular changes in Alzheimer's disease
Serum placental growth factor as a biomarker of cerebrovascular changes in Alzheimer's disease Open
Background While Alzheimer's disease (AD) biomarkers are now widely used, those focusing on vascular etiologies remain underdeveloped. Among candidates, angiogenesis markers appear particularly promising. Placental growth factor (PlGF) pla…
View article: Differential impact of eicosapentaenoic acid and docosahexaenoic acid in an animal model of Alzheimer’s disease
Differential impact of eicosapentaenoic acid and docosahexaenoic acid in an animal model of Alzheimer’s disease Open
Dietary supplementation with n-3 polyunsaturated fatty acids improves cognitive performance in several animal models of Alzheimer's disease (AD), an effect often associated with reduced amyloid-beta and/or tau pathologies. However, it rema…
View article: Additive neurorestorative effects of exercise and docosahexaenoic acid intake in a mouse model of Parkinson’s disease
Additive neurorestorative effects of exercise and docosahexaenoic acid intake in a mouse model of Parkinson’s disease Open
JOURNAL/nrgr/04.03/01300535-202502000-00033/figure1/v/2025-03-16T132329Z/r/image-tiff There is a need to develop interventions to slow or reverse the degeneration of dopamine neurons in Parkinson’s disease after diagnosis. Given that precl…
View article: Postsynaptic Protein Shank3a Deficiency Synergizes with Alzheimer's Disease Neuropathology to Impair Cognitive Performance in the 3xTg-AD Murine Model
Postsynaptic Protein Shank3a Deficiency Synergizes with Alzheimer's Disease Neuropathology to Impair Cognitive Performance in the 3xTg-AD Murine Model Open
Synaptic loss is intrinsically linked to Alzheimer's disease (AD) neuropathology and symptoms, but its direct impact on clinical symptoms remains elusive. The postsynaptic protein Shank3 (SH3 and multiple ankyrin repeat domains) is of part…
View article: Cerebrovascular insulin receptors are defective in Alzheimer’s disease
Cerebrovascular insulin receptors are defective in Alzheimer’s disease Open
Central response to insulin is suspected to be defective in Alzheimer’s disease. As most insulin is secreted in the bloodstream by the pancreas, its capacity to regulate brain functions must, at least partly, be mediated through the cerebr…
View article: Cerebrovascular insulin receptors are defective in Alzheimerˈs disease
Cerebrovascular insulin receptors are defective in Alzheimerˈs disease Open
Central response to insulin is suspected to be defective in Alzheimer’s disease (AD), but its localization in the brain remains unknown. While most insulin is secreted in the bloodstream by the pancreas, how it interacts with the blood-bra…
View article: Higher ACE2 expression in the brains of individuals with Alzheimer’s disease
Higher ACE2 expression in the brains of individuals with Alzheimer’s disease Open
BACKGROUND: The emergence of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is a major cause of death, particularly in the elderly. The geriatric population in which cognitive decline due to Alzheimer’s disease (AD) is freque…
View article: Interactions between insulin, the blood‐brain barrier, and beta‐amyloid in Alzheimer's disease
Interactions between insulin, the blood‐brain barrier, and beta‐amyloid in Alzheimer's disease Open
Background Defects in central response to insulin is suspected to play a role in AD. However, to act on the brain, pancreas‐secreted insulin must interact first with the blood‐brain barrier (BBB). The aim of the present study was to better…
View article: Sex-dependent alterations in the physiology of entorhinal cortex neurons in old heterozygous 3xTg-AD mice
Sex-dependent alterations in the physiology of entorhinal cortex neurons in old heterozygous 3xTg-AD mice Open
While the higher prevalence of Alzheimer Disease (AD) is clear, studies suggest that biological sex may also influence its pathogenesis. However, mechanisms behind these differences are not clear. To investigate physiological differences b…
View article: Sex-dependent alterations in the physiology of entorhinal cortex neurons in old heterozygous 3xTg-AD mice
Sex-dependent alterations in the physiology of entorhinal cortex neurons in old heterozygous 3xTg-AD mice Open
While the higher prevalence of Alzheimer Disease (AD) is clear, studies suggest that biological sex may also influence its pathogenesis . However, mechanisms behind these differences are not clear. To investigate physiological differences …
View article: Dietary intake of branched‐chain amino acids in a mouse model of Alzheimer's disease: Effects on survival, behavior, and neuropathology
Dietary intake of branched‐chain amino acids in a mouse model of Alzheimer's disease: Effects on survival, behavior, and neuropathology Open
Introduction High levels of plasmatic branched‐chain amino acids (BCAA), commonly used as dietary supplements, are linked to metabolic risk factors for Alzheimer's disease (AD). BCAA directly influence amino acid transport to the brain and…