Vincent Hellier
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View article: A food-sensitive olfactory circuit drives anticipatory satiety
A food-sensitive olfactory circuit drives anticipatory satiety Open
Food sensory perception has emerged as a potent regulator of specialized feeding circuits; yet, the consequences on feeding behaviour and the underlying neuronal basis remain poorly understood. Here, we reveal a sensory pathway that co-ord…
View article: The kisspeptin analog C6 reverses reproductive dysfunction in a mouse model of hyperprolactinemia
The kisspeptin analog C6 reverses reproductive dysfunction in a mouse model of hyperprolactinemia Open
In brief Kisspeptin has been shown to be tightly associated with hyperprolactinemia. This study shows that similar to kisspeptin, its analog C6 produces a reversal of HPRL estrus cycle and ovulation disruption. Abstract HPRL, characterized…
View article: Interactions between β‐endorphin and kisspeptin neurons of the ewe arcuate nucleus are modulated by photoperiod
Interactions between β‐endorphin and kisspeptin neurons of the ewe arcuate nucleus are modulated by photoperiod Open
Opioid peptides are well‐known modulators of the central control of reproduction. Among them, dynorphin coexpressed in kisspeptin (KP) neurons of the arcuate nucleus (ARC) has been thoroughly studied for its autocrine effect on KP release …
View article: Treating Mares with the Long-Acting Kisspeptin Analog C6 Increases Circulating Gonadotropins but Does Not Trigger Ovulation
Treating Mares with the Long-Acting Kisspeptin Analog C6 Increases Circulating Gonadotropins but Does Not Trigger Ovulation Open
The role of the neuropeptide kisspeptin (Kp) in mammalian reproduction is well established. Nevertheless, species-specific differences exist. In the horse, administration of the shortest endogenous Kp isoform, Kp10, is unable to trigger ov…
View article: A customized long acting formulation of the kisspeptin analog <scp>C6</scp> triggers ovulation in anestrus ewe
A customized long acting formulation of the kisspeptin analog <span>C6</span> triggers ovulation in anestrus ewe Open
The modulation of the kisspeptin system holds promise as a treatment for human reproductive disorders and for managing livestock breeding. The design of analogs has overcome some unfavorable properties of the endogenous ligands. However, f…
View article: The Role of Kisspeptin in Sexual Behavior
The Role of Kisspeptin in Sexual Behavior Open
Sexual behavior is essential for the perpetuation of a species. In female rodents, mate preference and lordosis behavior depend heavily on the integration of olfactory cues into the neuroendocrine brain, yet its underlying neural circuits …
View article: Estradiol‐induced neurogenesis in the female accessory olfactory bulb is required for the learning of the male odor
Estradiol‐induced neurogenesis in the female accessory olfactory bulb is required for the learning of the male odor Open
Odors processed by the main and accessory olfactory bulbs ( MOB , AOB ) are important for sexual behavior. Interestingly, both structures continue to receive new neurons during adulthood. A role for olfactory neurogenesis in sexual behavio…