Vincent Meynier
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View article: IRF4 haploinsufficiency in a multiplex family with Whipple’s disease
IRF4 haploinsufficiency in a multiplex family with Whipple’s disease Open
Tropheryma whipplei is the bacterial agent responsible for Whipple’s disease (WD). However, WD occurs only very rarely in T. whipplei-infected individuals. We investigated the cause of disease in two relatives with WD. We studied a son and…
View article: Advances in Human Pre-tRNA Maturation: TRMT10C and ELAC2 in Focus
Advances in Human Pre-tRNA Maturation: TRMT10C and ELAC2 in Focus Open
View article: Structural basis for human mitochondrial tRNA maturation
Structural basis for human mitochondrial tRNA maturation Open
View article: Advances in the Structural and Functional Understanding of m<sup>1</sup>A RNA Modification
Advances in the Structural and Functional Understanding of m<sup>1</sup>A RNA Modification Open
ConspectusRNA modification is a co- or post-transcriptional process by which specific nucleotides are chemically altered by enzymes after their initial incorporation into the RNA chain, expanding the chemical and functional diversity of RN…
View article: Synthesis of RNA-cofactor conjugates and structural exploration of RNA recognition by an m6A RNA methyltransferase
Synthesis of RNA-cofactor conjugates and structural exploration of RNA recognition by an m6A RNA methyltransferase Open
Chemical synthesis of RNA conjugates has opened new strategies to study enzymatic mechanisms in RNA biology. To gain insights into poorly understood RNA nucleotide methylation processes, we developed a new method to synthesize RNA-conjugat…
View article: A comprehensive review of m6A/m6Am RNA methyltransferase structures
A comprehensive review of m6A/m6Am RNA methyltransferase structures Open
Gene expression is regulated at many levels including co- or post-transcriptionally, where chemical modifications are added to RNA on riboses and bases. Expression control via RNA modifications has been termed ‘epitranscriptomics’ to keep …