Stephen J. Vincent
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View article: Contribution and Compensation Effects of Refracting Components to Ocular Aberrations in Keratoconus
Contribution and Compensation Effects of Refracting Components to Ocular Aberrations in Keratoconus Open
Keratoconic eyes exhibited higher anterior and posterior corneal aberrations than control eyes. The posterior cornea and lens compensated partly for the anterior cornea and total cornea, respectively, with greater percentage compensations …
View article: Evaluation of deep learning models for anterior segment OCT image segmentation during scleral lens wear
Evaluation of deep learning models for anterior segment OCT image segmentation during scleral lens wear Open
The U-Net++/VGG19 DL model displayed the best performance for AS-OCT image segmentation during scleral lens wear based on the overall Dice coefficient. Further assessment of DL models involving the segmentation of eyes with corneal disease…
View article: Intraocular pressure following long-term scleral lens wear in Chinese eyes
Intraocular pressure following long-term scleral lens wear in Chinese eyes Open
On average, IOP remained stable (mean changes < ± 0.3 mmHg) in Chinese participants with regular and irregular corneas following three months of scleral lens wear. Future long-term scleral lens studies examining changes in IOP with the len…
View article: Wide-angle fluid reservoir thickness changes during short-term scleral lens wear
Wide-angle fluid reservoir thickness changes during short-term scleral lens wear Open
Background To analyze the fluid reservoir thickness over the whole cornea during scleral lens settling using wide-angle optical coherence tomography (OCT) images and customized computer software. Methods A total of 75 participants were rec…
View article: Myopia Control Efficacy of Asymmetric Multipoint Defocus Technique Spectacle Lenses
Myopia Control Efficacy of Asymmetric Multipoint Defocus Technique Spectacle Lenses Open
The author(s) have no proprietary or commercial interest in any materials discussed in this article.
View article: The impact of toric contact lens correction upon functional near visual performance with digital devices
The impact of toric contact lens correction upon functional near visual performance with digital devices Open
Significant visual and functional benefits were found for digital near visual tasks associated with toric contact lens correction.
View article: Subfoveal choroidal thickness and axial length changes with orthokeratology in bilateral anisomyopia
Subfoveal choroidal thickness and axial length changes with orthokeratology in bilateral anisomyopia Open
Purpose To investigate the change in subfoveal choroidal thickness (SFChT) in bilateral anisomyopic children undergoing orthokeratology (ortho‐k) over 2 years and the association with axial elongation (AE). Methods SFChT, axial length and …
View article: Regional variations in corneal oedema during open‐eye fenestrated scleral lens wear
Regional variations in corneal oedema during open‐eye fenestrated scleral lens wear Open
Purpose To compare the magnitude of central, mid‐peripheral and peripheral stromal corneal oedema induced during short‐term fenestrated and non‐fenestrated scleral lens wear. Methods Nine healthy participants wore a non‐fenestrated and a f…
View article: Effect of 0.025% atropine on ocular biometry changes during accommodation
Effect of 0.025% atropine on ocular biometry changes during accommodation Open
Purpose Low concentration atropine is an effective treatment to slow myopia progression and axial elongation and also reduces accommodation. On‐axis ocular dimensions of the eye change during accommodation; hence, this study aimed to quant…
View article: The effect of near work on the anterior eye and associations with myopia: a narrative review
The effect of near work on the anterior eye and associations with myopia: a narrative review Open
The global prevalence of myopia has increased significantly in recent decades, and it is anticipated that half the population of the world will be myopic by 2050. The dramatic increase in myopia cannot be explained solely by genetic factor…
View article: Agreement between extrapolated corneoscleral topographical data obtained during natural and retracted eyelid positions
Agreement between extrapolated corneoscleral topographical data obtained during natural and retracted eyelid positions Open
Purpose To examine the influence of aperture size (corneoscleral data coverage) on extrapolated scleral sagittal height data generated by the Pentacam HR derived from the Corneo Scleral Profile (CSP) software, by comparing measurements obt…
View article: Quantifying tear exchange during rigid contact lens wear using corneoscleral profilometry: A proof of concept study
Quantifying tear exchange during rigid contact lens wear using corneoscleral profilometry: A proof of concept study Open
Introduction Tear exchange during contact lens wear is essential for ocular surface integrity, facilitating debris removal, and maintaining corneal metabolism. Fluorophotometry and fluorogram methods are typically used to measure tear exch…
View article: The central and peripheral corneal response to short‐term hypoxia
The central and peripheral corneal response to short‐term hypoxia Open
Purpose To quantify the magnitude and recovery of central and limbal corneal oedema induced by short‐term unilateral eyelid closure without contact lens wear. Methods The left eye of 10 adults with healthy corneas was patched using a folde…
View article: The effect of lens and fitting characteristics upon scleral lens centration
The effect of lens and fitting characteristics upon scleral lens centration Open
Purpose To quantify the impact of varying central fluid reservoir depth, lens thickness/mass and the addition of a peripheral fenestration upon scleral lens centration. Methods Ten young, healthy adults participated in a series of repeated…
View article: Enhancing OCT patch-based segmentation with improved GAN data augmentation and semi-supervised learning
Enhancing OCT patch-based segmentation with improved GAN data augmentation and semi-supervised learning Open
For optimum performance, deep learning methods, such as those applied for retinal and choroidal layer segmentation in optical coherence tomography (OCT) images, require sufficiently large and diverse labelled datasets for training. However…
View article: You've got to hide your myopia away: John Lennon's contact lenses
You've got to hide your myopia away: John Lennon's contact lenses Open
John Lennon has an enduring, instantly recognisable, iconic, spectacle look. However, prior to 1966, he was rarely seen wearing glasses in public. From ages 7 to 26, he effectively hid his myopia away, including a period of unsuccessful co…
View article: BCLA CLEAR Presbyopia: Management with corneal techniques
BCLA CLEAR Presbyopia: Management with corneal techniques Open
Corneal techniques for enhancing near and intermediate vision to correct presbyopia include surgical and contact lens treatment modalities. Broad approaches used independently or in combination include correcting one eye for distant and th…
View article: The effect of landing zone toricity on scleral lens fitting characteristics and optics
The effect of landing zone toricity on scleral lens fitting characteristics and optics Open
Purpose The fit and optical performance of a scleral lens is affected by the alignment of the landing zone with the underlying ocular surface. The aim of this research was to quantify the effect of landing zone toricity upon scleral lens f…
View article: George K. Smelser (1908–1973): Atmospheric oxygen and the corneal response to contact lens wear
George K. Smelser (1908–1973): Atmospheric oxygen and the corneal response to contact lens wear Open
Professor George Smelser was a scientist who played a crucial role in advancing the understanding of the anatomical and physiological changes within the cornea during contact lens wear. In a series of unique experiments conducted in the ea…
View article: Enhanced OCT chorio-retinal segmentation in low-data settings with semi-supervised GAN augmentation using cross-localisation
Enhanced OCT chorio-retinal segmentation in low-data settings with semi-supervised GAN augmentation using cross-localisation Open
Training deep learning methods for optical coherence tomography (OCT) retinal and choroidal layer segmentation is a challenge when data is scarce. In medical image analysis, this is often the case with a lack of data sharing due to confide…
View article: Central and peripheral scleral lens‐induced corneal oedema
Central and peripheral scleral lens‐induced corneal oedema Open
Purpose To quantify the magnitude of central and peripheral scleral lens‐induced corneal oedema for a range of fluid reservoir thicknesses, and to compare these experimental results with theoretical models of corneal oedema both with and w…
View article: Optical changes and association with axial elongation in children wearing orthokeratology lenses of different back optic zone diameter
Optical changes and association with axial elongation in children wearing orthokeratology lenses of different back optic zone diameter Open
Purpose To compare changes in ocular aberrations in children wearing orthokeratology (ortho-k) lenses with a back optic zone diameter (BOZD) of 6 mm (6-MM group) or 5 mm (5-MM group) and their associations with axial elongation (AE) over t…