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View article: Minimally Invasive vs Open Left Pancreatectomy for Resectable Pancreatic Cancer
Minimally Invasive vs Open Left Pancreatectomy for Resectable Pancreatic Cancer Open
Importance The DIPLOMA trial showed comparable radical resection rates after minimally invasive left pancreatectomy (MILP) and open left pancreatectomy (OLP) in patients with upfront resectable pancreatic cancer. Data on long-term overall …
View article: A positive resection margin does not determine long-term survival following colorectal liver metastasis resection
A positive resection margin does not determine long-term survival following colorectal liver metastasis resection Open
With the advent of modern perioperative systemic therapies, both hepatic recurrence and survival outcomes following hepatectomy for colorectal liver metastases seem unaffected by the presence of R1 resection margins.
View article: 51 Positive resection margin is not a determinant for long term survival after resection for colorectal liver metastasis
51 Positive resection margin is not a determinant for long term survival after resection for colorectal liver metastasis Open
Background Hepatic resection together with perioperative chemotherapy is currently the only treatment option that can offer a chance of long-term curative outcome in patients with colorectal liver metastases. The surgical margin status has…
View article: Pathological response following neoadjuvant immune checkpoint inhibitors in patients with hepatocellular carcinoma: a cross-trial, patient-level analysis
Pathological response following neoadjuvant immune checkpoint inhibitors in patients with hepatocellular carcinoma: a cross-trial, patient-level analysis Open
None.
View article: Delivering adjuvant and neoadjuvant treatments in the early stages of hepatocellular carcinoma
Delivering adjuvant and neoadjuvant treatments in the early stages of hepatocellular carcinoma Open
Both adjuvant and neoadjuvant regimens, notably those incorporating immune checkpoint inhibitors, demonstrated encouraging safety profiles and efficacy outcomes in HCC.While significant challenges persist, including optimizing patient sele…
View article: Minimally invasive versus open distal pancreatectomy for resectable pancreatic cancer (DIPLOMA): an international randomised non-inferiority trial
Minimally invasive versus open distal pancreatectomy for resectable pancreatic cancer (DIPLOMA): an international randomised non-inferiority trial Open
Medtronic Covidien AG, Johnson & Johnson Medical Limited, Dutch Gastroenterology Society.
View article: Impact of COVID-19 on 1-Year Survival Outcomes in Hepatocellular Carcinoma: A Multicenter Cohort Study
Impact of COVID-19 on 1-Year Survival Outcomes in Hepatocellular Carcinoma: A Multicenter Cohort Study Open
Introduction: The COVID-19 pandemic has caused severe disruption of healthcare services worldwide and interrupted patients’ access to essential services. During the first lockdown, many healthcare services were shut to all but emergencies.…
View article: Robot-Assisted Versus Laparoscopic Distal Pancreatectomy in Patients with Resectable Pancreatic Cancer: An International, Retrospective, Cohort Study
Robot-Assisted Versus Laparoscopic Distal Pancreatectomy in Patients with Resectable Pancreatic Cancer: An International, Retrospective, Cohort Study Open
Background Robot-assisted distal pancreatectomy (RDP) is increasingly used as an alternative to laparoscopic distal pancreatectomy (LDP) in patients with resectable pancreatic cancer but comparative multicenter studies confirming the safet…
View article: Impact of COVID19 on clinical outcomes in hepatocellular carcinoma:A multicentre cohort study
Impact of COVID19 on clinical outcomes in hepatocellular carcinoma:A multicentre cohort study Open
Introduction: The COVID-19 pandemic has caused severe disruption of healthcare services worldwide and interrupted patients’ access to essential services. During the first lockdown, many healthcare services were shut to all but emergencies.…
View article: Benchmarking of minimally invasive distal pancreatectomy with splenectomy: European multicentre study
Benchmarking of minimally invasive distal pancreatectomy with splenectomy: European multicentre study Open
Background Benchmarking is the process to used assess the best achievable results and compare outcomes with that standard. This study aimed to assess best achievable outcomes in minimally invasive distal pancreatectomy with splenectomy (MI…
View article: Phenotypic spectrum of serious cutaneous‐only adverse event following immunization with COVID‐19 vaccines: a multicentre case series and literature review
Phenotypic spectrum of serious cutaneous‐only adverse event following immunization with COVID‐19 vaccines: a multicentre case series and literature review Open
Journal Article Phenotypic spectrum of serious cutaneous‐only adverse event following immunization with COVID‐19 vaccines: a multicentre case series and literature review Get access M. Balogun, M. Balogun Birmingham Skin Centre, Sandwell a…
View article: The Impact of 68Gallium DOTA PET/CT in Managing Patients With Sporadic and Familial Pancreatic Neuroendocrine Tumours
The Impact of 68Gallium DOTA PET/CT in Managing Patients With Sporadic and Familial Pancreatic Neuroendocrine Tumours Open
Objective Pancreatic neuroendocrine tumours (panNETs) arise sporadically or as part of a genetic predisposition syndrome. CT/MRI, endoscopic ultrasonography and functional imaging using Octreoscan localise and stage disease. This study aim…
View article: Presentation and surgical management of a gossypiboma presenting with small bowel obstruction
Presentation and surgical management of a gossypiboma presenting with small bowel obstruction Open
Gossypiboma is a cotton-based foreign body retained within the human body following a surgical procedure. Transmural migration of intra-abdominal gossypiboma into the small bowel is rare; however, it can present with life-threatening compl…
View article: PRIME-HCC: phase Ib study of neoadjuvant ipilimumab and nivolumab prior to liver resection for hepatocellular carcinoma
PRIME-HCC: phase Ib study of neoadjuvant ipilimumab and nivolumab prior to liver resection for hepatocellular carcinoma Open
Background After liver resection (LR), patients with hepatocellular cancer (HCC) are at high risk of recurrence. There are no approved anti-cancer therapies known to affect such risk, highlighting the acute need for novel systemic therapie…
View article: The accuracy of pre-operative (P)-POSSUM scoring and cardiopulmonary exercise testing in predicting morbidity and mortality after pancreatic and liver surgery: A systematic review
The accuracy of pre-operative (P)-POSSUM scoring and cardiopulmonary exercise testing in predicting morbidity and mortality after pancreatic and liver surgery: A systematic review Open
POSSUM demonstrates an overall lack of predictive fit for morbidity, whilst CPET variables provide some predictive power for post-operative outcomes. Development of a new HPB specific risk prediction tool would be beneficial; the combinati…
View article: The role of surgery in chronic pancreatitis
The role of surgery in chronic pancreatitis Open
Chronic pancreatitis (CP) remains a complex condition resulting in significant morbidity and suffering in patients, often over a long period of time. Treatment is mostly centred on a conservative approach, with a variety of more aggressive…
View article: Multidisciplinary management of refractory insulinomas
Multidisciplinary management of refractory insulinomas Open
Summary Insulinomas are predominantly benign (~90%), pancreatic neuroendocrine tumours characterized by hyperinsulinaemic hypoglycaemia. They usually present as a small (<2 cm), well‐demarcated, solitary nodule that can arise in any part o…
View article: Does hepatitis B seroconversion affect survival outcome in patients with hepatitis B related hepatocellular carcinoma?
Does hepatitis B seroconversion affect survival outcome in patients with hepatitis B related hepatocellular carcinoma? Open
Little is known about whether hepatitis B surface antigen (HBsAg) seroconversion (SC) contributes to any survival benefits for patients with hepatocellular carcinoma (HCC).All patients with hepatitis B-related HCC and HBsAg seroclearance b…
View article: Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) procedure for hepatocellular carcinoma with chronic liver disease: a case report and review of literature
Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) procedure for hepatocellular carcinoma with chronic liver disease: a case report and review of literature Open
The incidence of complications after liver resection is closely related to functional future liver remnant (FLR). The standard approach to augment FLR is surgical or radiological occlusion of the artery or portal vein on the tumor side. As…