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View article: Allergic Rhinitis and Its Impact on Asthma ( <scp>ARIA</scp> )‐ <scp>EAACI</scp> Guidelines—2024–2025 Revision: Part I—Guidelines on Intranasal Treatments
Allergic Rhinitis and Its Impact on Asthma ( <span>ARIA</span> )‐ <span>EAACI</span> Guidelines—2024–2025 Revision: Part I—Guidelines on Intranasal Treatments Open
Background Allergic rhinitis (AR) impacts quality of life, work and school productivity. Over the last years, an important body of evidence resulting from mHealth data has led to a better understanding of AR. Such advances have motivated a…
View article: Underuse of allergen immunotherapy: a call to action
Underuse of allergen immunotherapy: a call to action Open
View article: Gender and Allergy: Mechanisms, Clinical Phenotypes, and Therapeutic Response—A Position Paper from the Società Italiana di Allergologia, Asma ed Immunologia Clinica (SIAAIC)
Gender and Allergy: Mechanisms, Clinical Phenotypes, and Therapeutic Response—A Position Paper from the Società Italiana di Allergologia, Asma ed Immunologia Clinica (SIAAIC) Open
Sex and gender play a critical role in allergic diseases, influencing immune response, clinical phenotypes, treatment strategies, outcomes, and health-related quality of life. Despite mounting evidence across multiple studies examining sex…
View article: The LUNET Project: Developing the Italian Systemic Erythematous Lupus Network
The LUNET Project: Developing the Italian Systemic Erythematous Lupus Network Open
Systemic lupus erythematosus (SLE) is a complex autoimmune disease that affects multiple organs and systems with a broad and heterogeneous spectrum of clinical manifestations. National disease-specific datasets and registries are crucial f…
View article: Comparing major COPD triple therapy trials using a structured multi-criteria decision analysis: A deep dive into patient populations and outcomes
Comparing major COPD triple therapy trials using a structured multi-criteria decision analysis: A deep dive into patient populations and outcomes Open
Among the therapies evaluated, FF/VI/UMEC achieved the highest composite MCDA score. However, optimal COPD management requires personalized treatment to be prescribed based on factors such as exacerbation history, previous ICS use, inhaler…
View article: Daily digital biomarkers in the follow-up and clustering of patients with asthma
Daily digital biomarkers in the follow-up and clustering of patients with asthma Open
Levels of digital biomarkers reflect asthma control patterns and might be used to monitor patients with asthma.
View article: Development and implementation of Phleos, a web-based tool for the data collection on Hypereosinophilic syndrome: the Italian Network on HES (INHES) study protocol
Development and implementation of Phleos, a web-based tool for the data collection on Hypereosinophilic syndrome: the Italian Network on HES (INHES) study protocol Open
Hypereosinophilic syndrome (HES) is a heterogeneous group of disorders characterised by persistent hypereosinophilia associated with organ damage. Due to its rarity and heterogeneity in its clinical presentation, HES remains underdiagnosed…
View article: Clinical and immunological biomarkers in hypereosinophilic syndrome: the second step after diagnostic algorithms
Clinical and immunological biomarkers in hypereosinophilic syndrome: the second step after diagnostic algorithms Open
Background Idiopathic hypereosinophilic syndrome currently represents a major unmet need for all medical specialties dealing with this disease. Markers capable of characterising the wide variability of its clinical presentation are current…
View article: Hypersensitivity Reactions to Iodinated Contrast Media: A Narrative Review of Current Evidence and Clinical Challenges
Hypersensitivity Reactions to Iodinated Contrast Media: A Narrative Review of Current Evidence and Clinical Challenges Open
Background/Objectives: Hypersensitivity reactions (HSRs) to iodinated contrast media (ICM), both immediate and non-immediate, pose clinical challenges despite using low-osmolality agents. This review aims to summarize current diagnostic ap…
View article: ARIA-Italy multidisciplinary consensus on nasal polyposis and biological treatments: Update 2025
ARIA-Italy multidisciplinary consensus on nasal polyposis and biological treatments: Update 2025 Open
In recent years, it was recognized that type-2 inflammation connects nasal polyposis and severe asthma (SA) in addition to other type-2 diseases. Thus, some biological drugs developed for SA appeared to exert a favourable effect also in na…
View article: Anaphylaxis Quality of Life Scale for adults: the validation on the Italian allergic patients
Anaphylaxis Quality of Life Scale for adults: the validation on the Italian allergic patients Open
Background. The aim of this study is to translate and validate the Italian Version of the Anaphylaxis Quality of Life Scale for Adults (A-QoL-Adults), made up of the three subscales Social impact (SQoL), Emotional impact (EQol) and …
View article: Adherence to Treatment in Allergic Rhinitis During the Pollen Season in Europe: A MASK‐air Study
Adherence to Treatment in Allergic Rhinitis During the Pollen Season in Europe: A MASK‐air Study Open
Background Adherence to rhinitis treatment has been insufficiently assessed. We aimed to use data from the MASK‐air mHealth app to assess adherence to oral antihistamines (OAH), intra‐nasal corticosteroids (INCS) or azelastine‐fluticasone …
View article: Allergic Rhinitis and its Impact on Asthma (ARIA) Classes in MASK-air Users
Allergic Rhinitis and its Impact on Asthma (ARIA) Classes in MASK-air Users Open
Background: The Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines classify rhinitis as "intermittent" or "persistent" and "mild" or "moderate-severe". Objectives: To assess ARIA classes in a real-world study in terms of phenotyp…
View article: Challenges in treating patients with comorbid asthma and bronchiectasis
Challenges in treating patients with comorbid asthma and bronchiectasis Open
The management of patients with overlapping asthma and bronchiectasis requires a tailored approach, starting with a comprehensive assessment of the patient's clinical profile, including the severity of asthma and the extent of bronchiectas…
View article: Evaluating the impact of changing inhaler color on perception of symptoms and disease burden in patients with asthma: the FEEL study
Evaluating the impact of changing inhaler color on perception of symptoms and disease burden in patients with asthma: the FEEL study Open
Changing inhaler color had no impact on asthma symptoms, but did have a numerical impact on patients' expectations of subsequent treatment effect. This emphasizes the importance of communication between patients and healthcare practitioner…
View article: Concurrent validity, cut‐offs and ability to change of patient‐reported outcome measures for rhinitis and asthma in MASK‐air<sup>®</sup>
Concurrent validity, cut‐offs and ability to change of patient‐reported outcome measures for rhinitis and asthma in MASK‐air<sup>®</sup> Open
Patient‐reported outcome measures (PROMs) are used to assess a patient's health status at a particular point in time. They are essential in the development of person‐centred care. This paper reviews studies performed on PROMs for assessing…
View article: Asthma severity: the patient’s point of view
Asthma severity: the patient’s point of view Open
This study highlights the disparity between clinical categorization and patient perceptions of asthma severity. The prevalence of self reported severe asthma exceeds literature data. The burden of mild asthma remains significant, with trea…
View article: Anti-Herpes Zoster Vaccination of Fragile Patients in Hospital Setting: A Nudge Intervention in Italy
Anti-Herpes Zoster Vaccination of Fragile Patients in Hospital Setting: A Nudge Intervention in Italy Open
Background: A nudge intervention against Herpes Zoster, created and implemented in Italy, is presented in order to administer the Shingrix vaccine on a sample of frail patients, as required by the National Prevention Plan. Individual and c…
View article: Asthma management, focused on the use of oral corticosteroids: the opinions of Italian asthmatic patients
Asthma management, focused on the use of oral corticosteroids: the opinions of Italian asthmatic patients Open
The survey results confirmed many problems related to mild-moderate and severe asthma management in Italy and highlighted the overuse of OCS rather than more effective and safe treatments, which had strong negative effects on HRQoL.
View article: Poor Rhinitis and Asthma Control Is Associated With Decreased Health-Related Quality of Life and Utilities: A MASK-air Study
Poor Rhinitis and Asthma Control Is Associated With Decreased Health-Related Quality of Life and Utilities: A MASK-air Study Open
View article: Severe atopic dermatitis treated with anti-interleukin 4Rα reduces the psychological burden in patients with and without alexithymia
Severe atopic dermatitis treated with anti-interleukin 4Rα reduces the psychological burden in patients with and without alexithymia Open
View article: A 52-week multicenter retrospective real-world study on effectiveness and safety of dupilumab in children with atopic dermatitis aged from 6 to 11 years
A 52-week multicenter retrospective real-world study on effectiveness and safety of dupilumab in children with atopic dermatitis aged from 6 to 11 years Open
Background: Dupilumab has been shown to be a safe and effective drug for the treatment of atopic dermatitis (AD) in children from 6 months to 11 years in randomized clinical trials. Aim: The aim of this real-life study was to determ…
View article: Impairment of EQ-5D-5L Domains According to Allergic Rhinitis and Asthma Control: A MASK-air Real-World Study
Impairment of EQ-5D-5L Domains According to Allergic Rhinitis and Asthma Control: A MASK-air Real-World Study Open
View article: Severe Asthma Network Italy Definition of Clinical Remission in Severe Asthma: A Delphi Consensus
Severe Asthma Network Italy Definition of Clinical Remission in Severe Asthma: A Delphi Consensus Open
View article: Improvement of daily allergy control by sublingual immunotherapy: A <scp>MASK</scp>‐air® study
Improvement of daily allergy control by sublingual immunotherapy: A <span>MASK</span>‐air® study Open
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View article: Patient‐centered digital biomarkers for allergic respiratory diseases and asthma: The <scp>ARIA‐EAACI</scp> approach – ARIA‐EAACI Task Force Report
Patient‐centered digital biomarkers for allergic respiratory diseases and asthma: The <span>ARIA‐EAACI</span> approach – ARIA‐EAACI Task Force Report Open
Biomarkers for the diagnosis, treatment and follow‐up of patients with rhinitis and/or asthma are urgently needed. Although some biologic biomarkers exist in specialist care for asthma, they cannot be largely used in primary care. There ar…
View article: Rhinitis associated with asthma is distinct from rhinitis alone: The <scp>ARIA‐MeDALL</scp> hypothesis
Rhinitis associated with asthma is distinct from rhinitis alone: The <span>ARIA‐MeDALL</span> hypothesis Open
Asthma, rhinitis, and atopic dermatitis (AD) are interrelated clinical phenotypes that partly overlap in the human interactome. The concept of “one‐airway‐one‐disease,” coined over 20 years ago, is a simplistic approach of the links betwee…
View article: Digitally‐enabled, patient‐centred care in rhinitis and asthma multimorbidity: The ARIA‐MASK‐air<sup>®</sup>approach
Digitally‐enabled, patient‐centred care in rhinitis and asthma multimorbidity: The ARIA‐MASK‐air<sup>®</sup>approach Open
MASK‐air ® , a validated mHealth app (Medical Device regulation Class IIa) has enabled large observational implementation studies in over 58,000 people with allergic rhinitis and/or asthma. It can help to address unmet patient needs in rhi…
View article: Consistent trajectories of rhinitis control and treatment in 16,177 weeks: The <scp>MASK</scp>‐air® longitudinal study
Consistent trajectories of rhinitis control and treatment in 16,177 weeks: The <span>MASK</span>‐air® longitudinal study Open
Introduction Data from mHealth apps can provide valuable information on rhinitis control and treatment patterns. However, in MASK‐air®, these data have only been analyzed cross‐sectionally, without considering the changes of symptoms over …
View article: Real‐world data using mHealth apps in rhinitis, rhinosinusitis and their multimorbidities
Real‐world data using mHealth apps in rhinitis, rhinosinusitis and their multimorbidities Open
Digital health is an umbrella term which encompasses eHealth and benefits from areas such as advanced computer sciences. eHealth includes mHealth apps, which offer the potential to redesign aspects of healthcare delivery. The capacity of a…