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View article: Clinical and MRI features contributing to the clinico-radiological dissociation in a large cohort of people with multiple sclerosis
Clinical and MRI features contributing to the clinico-radiological dissociation in a large cohort of people with multiple sclerosis Open
View article: The Role of Cerebellum and Basal Ganglia Functional Connectivity in Altered Voluntary Movement Execution in Essential Tremor
The Role of Cerebellum and Basal Ganglia Functional Connectivity in Altered Voluntary Movement Execution in Essential Tremor Open
Substantial evidence highlights the role of the cerebellum in the pathophysiology of tremor in essential tremor (ET), although its potential involvement in altered movement execution in this condition remains unclear. This study aims to ex…
View article: The Impact of Cytomegalovirus Infection on Natural Killer and CD8+ T Cell Phenotype in Multiple Sclerosis
The Impact of Cytomegalovirus Infection on Natural Killer and CD8+ T Cell Phenotype in Multiple Sclerosis Open
Multiple sclerosis (MS) is a debilitating neurological disease that has been classified as an immune-mediated attack on myelin, the protective sheath of nerves. Some aspects of its pathogenesis are still unclear; nevertheless, it is genera…
View article: Neurophysiological and clinical biomarkers of secondary progressive multiple sclerosis: A cross-sectional study
Neurophysiological and clinical biomarkers of secondary progressive multiple sclerosis: A cross-sectional study Open
Timely diagnosis of secondary progressive multiple sclerosis (SPMS) represents a clinical challenge. The Frailty Index, a quantitative frailty measure, and the Neurophysiological Index, a combined measure of sensorimotor cortex inhibitory …
View article: Neural bases of motor fatigue in multiple sclerosis: A multimodal approach using neuromuscular assessment and TMS-EEG
Neural bases of motor fatigue in multiple sclerosis: A multimodal approach using neuromuscular assessment and TMS-EEG Open
View article: Finding the source of motor fatigue in multiple sclerosis: a transcranial magnetic stimulation - electroencephalography study
Finding the source of motor fatigue in multiple sclerosis: a transcranial magnetic stimulation - electroencephalography study Open
View article: Multiple sclerosis-disease modifying therapies affect humoral and T-cell response to mRNA COVID-19 vaccine
Multiple sclerosis-disease modifying therapies affect humoral and T-cell response to mRNA COVID-19 vaccine Open
Background The mRNA vaccines help protect from COVID-19 severity, however multiple sclerosis (MS) disease modifying therapies (DMTs) might affect the development of humoral and T-cell specific response to vaccination. Methods The aim of th…
View article: The impact of PM2.5, PM10 and NO2 on Covid-19 severity in a sample of patients with multiple sclerosis: A case-control study
The impact of PM2.5, PM10 and NO2 on Covid-19 severity in a sample of patients with multiple sclerosis: A case-control study Open
View article: Evaluation of the Psychometric Properties of the Health Assessment Questionnaire (HAQ) in a Population of Individuals With Multiple Sclerosis
Evaluation of the Psychometric Properties of the Health Assessment Questionnaire (HAQ) in a Population of Individuals With Multiple Sclerosis Open
Introduction The Health Assessment Questionnaire (HAQ) has been translated into many languages and it has been classified as the predictor of disability and medical costs, however, the psychometric properties of the HAQ have never been stu…
View article: Correction to: Prevalence and predictors of bowel dysfunction in a large multiple sclerosis outpatient population: an Italian multicenter study
Correction to: Prevalence and predictors of bowel dysfunction in a large multiple sclerosis outpatient population: an Italian multicenter study Open
View article: Evaluation of the Psychometric Properties of Jebsen Taylor Hand Function Test (JTHFT) in Italian Individuals With Multiple Sclerosis
Evaluation of the Psychometric Properties of Jebsen Taylor Hand Function Test (JTHFT) in Italian Individuals With Multiple Sclerosis Open
Introduction The Jebsen Taylor Hand Function Test (JTHFT) is a non-diagnostic assessment scale for hand and upper limb dexterity that is commonly used in various countries around the world for diseases, such as muscular dystrophy, stroke, …
View article: Are Neurophysiological Biomarkers Able to Discriminate Multiple Sclerosis Clinical Subtypes?
Are Neurophysiological Biomarkers Able to Discriminate Multiple Sclerosis Clinical Subtypes? Open
Secondary progressive multiple sclerosis (SPMS) subtype is retrospectively diagnosed, and biomarkers of the SPMS are not available. We aimed to identify possible neurophysiological markers exploring grey matter structures that could be use…
View article: Infectious risk in multiple sclerosis patients treated with disease-modifying therapies: A three-year observational cohort study
Infectious risk in multiple sclerosis patients treated with disease-modifying therapies: A three-year observational cohort study Open
Background The disease-modifying therapies (DMTs) largely used in multiple sclerosis (MS) may result in higher infectious risk. Objective We aimed to investigate the infectious risk in DMT-treated MS patients. Methods MS patients were eval…
View article: The effect of stimulation frequency on transcranial evoked potentials
The effect of stimulation frequency on transcranial evoked potentials Open
Introduction Transcranial magnetic stimulation-evoked electroencephalography potentials (TEPs) have been used to study motor cortical excitability in healthy subjects and several neurological conditions. However, optimal recording paramete…
View article: COVID-19 Severity in Multiple Sclerosis
COVID-19 Severity in Multiple Sclerosis Open
Background and Objectives It is unclear how multiple sclerosis (MS) affects the severity of COVID-19. The aim of this study is to compare COVID-19–related outcomes collected in an Italian cohort of patients with MS with the outcomes expect…
View article: Effect of Botulinum Toxin on Non-Motor Symptoms in Cervical Dystonia
Effect of Botulinum Toxin on Non-Motor Symptoms in Cervical Dystonia Open
Patients with cervical dystonia (CD) may display non-motor symptoms, including psychiatric disturbances, pain, and sleep disorders. Intramuscular injection of botulinum toxin type A (BoNT-A) is the most efficacious treatment for motor symp…
View article: Prevalence and predictors of bowel dysfunction in a large multiple sclerosis outpatient population: an Italian multicenter study
Prevalence and predictors of bowel dysfunction in a large multiple sclerosis outpatient population: an Italian multicenter study Open
View article: SARS-CoV-2 serology after COVID-19 in multiple sclerosis: An international cohort study
SARS-CoV-2 serology after COVID-19 in multiple sclerosis: An international cohort study Open
Background: The MuSC-19 project is an Italian cohort study open to international partners that collects data on multiple sclerosis (MS) patients with COVID-19. During the second wave of the pandemic, serological tests became routinely avai…
View article: Attention-Demanding Cognitive Tasks Worsen Postural Control in Patients With Cervical Dystonia: A Case-Control Study
Attention-Demanding Cognitive Tasks Worsen Postural Control in Patients With Cervical Dystonia: A Case-Control Study Open
Background: Patients with cervical dystonia (CD) show impaired postural control, balance, and gait, likely due to abnormal head postures and sensorimotor disturbances. However, until now no study has investigated whether attention-demandin…
View article: Botulinum Toxin Effects on Sensorimotor Integration in Focal Dystonias
Botulinum Toxin Effects on Sensorimotor Integration in Focal Dystonias Open
(1) Background: In dystonia, the somatosensory temporal discrimination threshold (STDT) is abnormally increased at rest and higher and longer-lasting during movement execution in comparison with healthy subjects (HS), suggesting an abnorma…
View article: Cortical M1 plasticity and metaplasticity in patients with multiple sclerosis
Cortical M1 plasticity and metaplasticity in patients with multiple sclerosis Open
View article: Abnormal Temporal Coupling of Tactile Perception and Motor Action in Parkinson’s Disease
Abnormal Temporal Coupling of Tactile Perception and Motor Action in Parkinson’s Disease Open
Evidence shows altered somatosensory temporal discrimination threshold (STDT) in Parkinson's disease in comparison to normal subjects. In healthy subjects, movement execution modulates STDT values through mechanisms of sensory gating. We i…