Violaine Hubert
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View article: Solution-based studies on the contact between the complement receptor 3 ligand-binding domain and simvastatin
Solution-based studies on the contact between the complement receptor 3 ligand-binding domain and simvastatin Open
View article: Author response: MorphoCellSorter is an Andrews plot-based sorting approach to rank microglia according to their morphological features
Author response: MorphoCellSorter is an Andrews plot-based sorting approach to rank microglia according to their morphological features Open
View article: MorphoCellSorter is an Andrews plot-based sorting approach to rank microglia according to their morphological features
MorphoCellSorter is an Andrews plot-based sorting approach to rank microglia according to their morphological features Open
Microglia exhibit diverse morphologies reflecting environmental conditions, maturity, or functional states. Thus, morphological characterization provides important information to understand microglial roles and functions. Most recent morph…
View article: Author response: MorphoCellSorter: An Andrews plot-based sorting approach to rank microglia according to their morphological features
Author response: MorphoCellSorter: An Andrews plot-based sorting approach to rank microglia according to their morphological features Open
View article: MorphoCellSorter: An Andrews plot-based sorting approach to rank microglia according to their morphological features
MorphoCellSorter: An Andrews plot-based sorting approach to rank microglia according to their morphological features Open
Microglia exhibit diverse morphologies reflecting environmental conditions, maturity or functional states. Thus, morphological characterization provides important information to understand microglial roles and functions. Most recent morpho…
View article: MorphoCellSorter: An Andrews plot-based sorting approach to rank microglia according to their morphological features
MorphoCellSorter: An Andrews plot-based sorting approach to rank microglia according to their morphological features Open
Microglia exhibit diverse morphologies reflecting environmental conditions, maturity or functional states. Thus, morphological characterization provides important information to understand microglial roles and functions. Most recent morpho…
View article: MorphoCellSorter is an Andrews plot-based sorting approach to rank microglia according to their morphological features
MorphoCellSorter is an Andrews plot-based sorting approach to rank microglia according to their morphological features Open
Microglia exhibit diverse morphologies reflecting environmental conditions, maturity, or functional states. Thus, morphological characterization provides important information to understand microglial roles and functions. Most recent morph…
View article: Author response: MorphoCellSorter: An Andrews plot-based sorting approach to rank microglia according to their morphological features
Author response: MorphoCellSorter: An Andrews plot-based sorting approach to rank microglia according to their morphological features Open
View article: MorphoCellSorter: An Andrews plot-based sorting approach to rank microglia according to their morphological features
MorphoCellSorter: An Andrews plot-based sorting approach to rank microglia according to their morphological features Open
Microglia exhibit diverse morphologies reflecting environmental conditions, maturity or functional states. Thus, morphological characterization provides important information to understand microglial roles and functions. Most recent morpho…
View article: Use of metal-based contrast agents for in vivo MR and CT imaging of phagocytic cells in neurological pathologies
Use of metal-based contrast agents for in vivo MR and CT imaging of phagocytic cells in neurological pathologies Open
The activation of phagocytic cells is a hallmark of many neurological diseases. Imaging them in their 3-dimensional cerebral environment over time is crucial to better understand their role in disease pathogenesis and to monitor their pote…
View article: Neurofunctional and neuroimaging readouts for designing a preclinical stem-cell therapy trial in experimental stroke
Neurofunctional and neuroimaging readouts for designing a preclinical stem-cell therapy trial in experimental stroke Open
View article: Neurofunctional and neuroimaging readouts for designing a preclinical stem-cell therapy trial in experimental stroke
Neurofunctional and neuroimaging readouts for designing a preclinical stem-cell therapy trial in experimental stroke Open
With the aim of designing a preclinical study evaluating an intracerebral cell-based therapy for stroke, an observational study was performed in the rat suture model of ischemic stroke. Objectives were threefold: (i) to characterize neurof…
View article: Multimodal Imaging with NanoGd Reveals Spatiotemporal Features of Neuroinflammation after Experimental Stroke
Multimodal Imaging with NanoGd Reveals Spatiotemporal Features of Neuroinflammation after Experimental Stroke Open
The purpose of this study is to propose and validate a preclinical in vivo magnetic resonance imaging (MRI) tool to monitor neuroinflammation following ischemic stroke, based on injection of a novel multimodal nanoprobe, NanoGd, specifical…
View article: Brain virtual histology with X-ray phase-contrast tomography Part I: whole-brain myelin mapping in white-matter injury models
Brain virtual histology with X-ray phase-contrast tomography Part I: whole-brain myelin mapping in white-matter injury models Open
White-matter injury leads to severe functional loss in many neurological diseases. Myelin staining on histological samples is the most common technique to investigate white-matter fibers. However, tissue processing and sectioning may affec…
View article: Hybrid multimodal contrast agent for multiscale <i>in vivo</i> investigation of neuroinflammation
Hybrid multimodal contrast agent for multiscale <i>in vivo</i> investigation of neuroinflammation Open
Hybrid nanoprobe specifically designed to use as a contrast agent targeting phagocytic cells in an animal model of ischemic stroke and imaging using MRI, intravital two-photon microscopy and phase contrast X-rays imaging.
View article: Multimodal imaging with NanoGd reveals spatiotemporal features of neuroinflammation after experimental stroke
Multimodal imaging with NanoGd reveals spatiotemporal features of neuroinflammation after experimental stroke Open
Excel file for cell culture, MRI and two-photon microscopy quantitative analyses. These are the data used for the statistical analyses.
View article: Multicolor spectral photon counting CT monitors and quantifies therapeutic cells and their encapsulating scaffold in a model of brain damage
Multicolor spectral photon counting CT monitors and quantifies therapeutic cells and their encapsulating scaffold in a model of brain damage Open
Rationale & aim: Various types of cell therapies are currently under investigation for the treatment of ischemic stroke patients. To bridge the gap between cell administration and therapeutic outcome, there is a need for non-invasiv…
View article: Magnetic Resonance Imaging of cerebral phagocytic cells in mouse model of neuroinflammation
Magnetic Resonance Imaging of cerebral phagocytic cells in mouse model of neuroinflammation Open
L’accident vasculaire cérébral ischémique (AVCi) est un enjeu majeur de santé publique. L’imagerie par résonance magnétique (IRM) est de plus en plus utilisée pour la prise en charge en urgence des patients, afin de sélectionner les patien…
View article: Imagerie par Résonance Magnétique des cellules phagocytaires cérébrales dans des modèles murins de neuroinflammation
Imagerie par Résonance Magnétique des cellules phagocytaires cérébrales dans des modèles murins de neuroinflammation Open
Stroke is a major public health issue. Magnetic resonance imaging (MRI) is increasingly used for the emergency management of these patients, during the interruption of blood flow to better select patients who are candidates for reperfusion…
View article: MRI coupled with clinically-applicable iron oxide nanoparticles reveals choroid plexus involvement in a murine model of neuroinflammation
MRI coupled with clinically-applicable iron oxide nanoparticles reveals choroid plexus involvement in a murine model of neuroinflammation Open
View article: Clinical Imaging of Choroid Plexus in Health and in Brain Disorders: A Mini-Review
Clinical Imaging of Choroid Plexus in Health and in Brain Disorders: A Mini-Review Open
The choroid plexuses (ChPs) perform indispensable functions for the development, maintenance and functioning of the brain. Although they have gained considerable interest in the last years, their involvement in brain disorders is still lar…
View article: High throughput three-dimensional imaging of myelin fibers in the whole mouse brain
High throughput three-dimensional imaging of myelin fibers in the whole mouse brain Open
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View article: Exercise Does Not Protect against Peripheral and Central Effects of a High Cholesterol Diet Given Ad libitum in Old ApoE−/− Mice
Exercise Does Not Protect against Peripheral and Central Effects of a High Cholesterol Diet Given Ad libitum in Old ApoE−/− Mice Open
Aim: Advanced atherosclerosis increases inflammation and stroke risk in the cerebral vasculature. Exercise is known to improve cardio-metabolic profiles when associated with a caloric restriction, but it remains debated whether it i…
View article: Multiparametric magnetic resonance imaging including oxygenation mapping of experimental ischaemic stroke
Multiparametric magnetic resonance imaging including oxygenation mapping of experimental ischaemic stroke Open
Recent advances in MRI methodology, such as microvascular and brain oxygenation (StO 2 ) imaging, may prove useful in obtaining information about the severity of the acute stroke. We assessed the potential of StO 2 to detect the ischaemic …