Virginie Dormoy-Raclet
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View article: HuR counteracts miR-330 to promote STAT3 translation during inflammation-induced muscle wasting
HuR counteracts miR-330 to promote STAT3 translation during inflammation-induced muscle wasting Open
Significance Proinflammatory diseases, such as cancer, AIDS, and chronic obstructive pulmonary diseases, are often associated with a progressive loss of skeletal muscle tissue, a syndrome also known as cachexia. Cytokines trigger muscle lo…
View article: Neuroinflammation, mitochondrial defects and neurodegeneration in mucopolysaccharidosis III type C mouse model
Neuroinflammation, mitochondrial defects and neurodegeneration in mucopolysaccharidosis III type C mouse model Open
Severe progressive neurological paediatric disease mucopolysaccharidosis III type C is caused by mutations in the HGSNAT gene leading to deficiency of acetyl-CoA: α-glucosaminide N-acetyltransferase involved in the lysosomal catabolism of …