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View article: Palliative MRI-guided transurethral ultrasound ablation for symptomatic locally advanced prostate cancer
Palliative MRI-guided transurethral ultrasound ablation for symptomatic locally advanced prostate cancer Open
Locally advanced prostate cancer can cause bladder outlet obstruction, gross hematuria and frequent hospitalization. While these complications are commonly treated by palliative transurethral resection of the prostate, the improvement is o…
View article: Palliative MRI-guided transurethral ultrasound ablation for symptomatic locally advanced prostate cancer
Palliative MRI-guided transurethral ultrasound ablation for symptomatic locally advanced prostate cancer Open
Locally advanced prostate cancer can cause bladder outlet obstruction, gross hematuria and frequent hospitalization. While these complications are commonly treated by palliative transurethral resection of the prostate, the improvement is o…
View article: Oxytocin selectively reduces blood flow in uterine fibroids without an effect on myometrial blood flow: a dynamic contrast enhanced MRI evaluation
Oxytocin selectively reduces blood flow in uterine fibroids without an effect on myometrial blood flow: a dynamic contrast enhanced MRI evaluation Open
Oxytocin is effective in decreasing the blood flow in fibroids while having minor or no effect on the blood flow of normal myometrium. Routine use of oxytocin in HIFU therapy may make the therapy suitable to a larger group of women in a sa…
View article: Feasibility of MRI-guided transurethral ultrasound for lesion-targeted ablation of prostate cancer
Feasibility of MRI-guided transurethral ultrasound for lesion-targeted ablation of prostate cancer Open
Background: MRI-guided transurethral ultrasound ablation (TULSA) has been evaluated for organ-confined prostate cancer (PCa). The purpose of this study was to assess the safety and toxicity, accuracy and short-term evolution of cell-death …
View article: High-Intensity Focused Ultrasound Therapy in the Uterine Fibroid: A Clinical Case Study of Poor Heating Efficacy
High-Intensity Focused Ultrasound Therapy in the Uterine Fibroid: A Clinical Case Study of Poor Heating Efficacy Open
A clinical case study of high-intensity focused ultrasound (HIFU) treatment in the uterine fibroid was conducted. During the therapy, poor heating efficacy was observed which could be attributed to several factors such as the local perfusi…
View article: Histopathological evaluation of prostate specimens after thermal ablation may be confounded by the presence of thermally-fixed cells
Histopathological evaluation of prostate specimens after thermal ablation may be confounded by the presence of thermally-fixed cells Open
Purpose: Prostate cancer can be eradicated with heat exposure. However, high and rapid temperature elevations may cause thermofixation giving the appearance of viable tissue. The purpose was to characterize the immunoprofile and evaluate t…
View article: Transurethral ultrasound therapy of the prostate in the presence of calcifications: A simulation study
Transurethral ultrasound therapy of the prostate in the presence of calcifications: A simulation study Open
Purpose Transurethral ultrasound therapy is an investigational treatment modality which could potentially be used for the localized treatment of prostate cancer. One of the limiting factors of this therapy is prostatic calcifications. Thes…
View article: Full Modeling of High-Intensity Focused Ultrasound and Thermal Heating in the Kidney Using Realistic Patient Models
Full Modeling of High-Intensity Focused Ultrasound and Thermal Heating in the Kidney Using Realistic Patient Models Open
Objective: High-intensity focused ultrasound (HIFU) therapy can be used for non-invasive treatment of kidney (renal) cancer, but the clinical outcomes have been variable. In this study, the efficacy of renal HIFU therapy was studied using …
View article: The effect of temperature dependent tissue parameters on acoustic radiation force induced displacements
The effect of temperature dependent tissue parameters on acoustic radiation force induced displacements Open
Multiple ultrasound elastography techniques rely on acoustic radiation force (ARF) in monitoring high-intensity focused ultrasound (HIFU) therapy. However, ARF is dependent on tissue attenuation and sound speed, both of which are also know…
View article: Nonlinear 3-D simulation of high-intensity focused ultrasound therapy in the Kidney
Nonlinear 3-D simulation of high-intensity focused ultrasound therapy in the Kidney Open
Kidney cancer is a severe disease which can be treated non-invasively using high-intensity focused ultrasound (HIFU) therapy. However, tissue in front of the transducer and the deep location of kidney can cause significant losses to the ef…
View article: The feasibility of ultrasound elastography in monitoring high-intensity focused ultrasound therapy
The feasibility of ultrasound elastography in monitoring high-intensity focused ultrasound therapy Open
High-intensity focused ultrasound (HIFU) therapy is a non-invasive therapy method for the treatment of solid tumours. One of the main barriers to wider clinical adoption of HIFU is the lack of reliable and cost-efficient therapy monitoring…