Vishal Gulecha
YOU?
Author Swipe
View article: Design and evaluation of cost-effective oro-dispersible tablets of venlafaxine hydrochloride by effervescent method
Design and evaluation of cost-effective oro-dispersible tablets of venlafaxine hydrochloride by effervescent method Open
Background: Venlafaxine hydrochloride (VFH) is an antidepressant drug with poor bioavailability due to extensive first-pass metabolism. Objective: In the present study, oro-dispersible VFH tablets were prepared using an effervescent method…
View article: Formulation and Evaluation of Budesonide-loaded Nanosponges for Colon-specific Drug Delivery Systems
Formulation and Evaluation of Budesonide-loaded Nanosponges for Colon-specific Drug Delivery Systems Open
Background: The purpose of this work was to complex budesonide with cyclodextrin-based nanosponges to improve its solubility and stability. The current study focused on polysaccharide systems that have undergone minimal chemical alteration…
View article: Preparation, Optimization, Characterization, and Evaluation of Rosuvastatin Loaded Solid Lipid Nanoparticles Using Quality by Design Approach
Preparation, Optimization, Characterization, and Evaluation of Rosuvastatin Loaded Solid Lipid Nanoparticles Using Quality by Design Approach Open
The present research work aims to prepare and characterize solid lipid nanoparticles (SLN) containing rosuvastatin calcium (RT). We aim to use a novel microwave-assisted microemulsion technique to produce Rosuvastatin-loaded SLN. The chara…
View article: Pharmacokinetic Evaluation of Telmisartan and Cilnidipine Bilayer Tablet in A Rabbit Model
Pharmacokinetic Evaluation of Telmisartan and Cilnidipine Bilayer Tablet in A Rabbit Model Open
Hypertension is a chronic medical condition affecting a significant proportion of the global population. It is a major risk factor for cardiovascular diseases, stroke, and kidney failure. Telmisartan and cilnidipine combination are commonl…
View article: Buccal drug delivery system
Buccal drug delivery system Open
The buccal area of the oral mucosa provides an adorable channel of systemic medication distribution within the mouth mucosa. Drugs are delivered via oral mucosal layer, that has a higher first-pass metabolism and degrades gastrointestinal.…
View article: Nanobubbles: Fundamentals and recent drug delivery applications
Nanobubbles: Fundamentals and recent drug delivery applications Open
The emerging branch in pharmaceutical sciences known as pharmaceutical nanotechnology presents new tools, opportunities and scope, which are expected to have significant applications, in disease diagnostics and therapeutics. There is a gro…
View article: In-vitro anti-lithiatic activity study of Meyna laxiflora seeds and Tectona grandis bark
In-vitro anti-lithiatic activity study of Meyna laxiflora seeds and Tectona grandis bark Open
This study involves the evaluation of Meyna laxiflora seeds and Tectona grandis bark for antiurolithatic activity. Homogeneous precipitation method was used for In-vitro anti-lithiatic activity on generated calcium oxalate crystals. Extrac…
View article: Protective Effects of Lantana camara (aculeata) in Rheumatoid arthritis using in vitro and in vivo Complete Freund’s Adjuvant induced arthritis in rats
Protective Effects of Lantana camara (aculeata) in Rheumatoid arthritis using in vitro and in vivo Complete Freund’s Adjuvant induced arthritis in rats Open
The main objective of the present work is to evaluate the potential of Lantana camara (aculeata) for anti-arthritic activity using in vitro and in vivo study. L. camara is an important medicinal, ornamental, and essential oil-producing her…
View article: Amelioration of CFA induced arthritis in rats by buchnania lanzan
Amelioration of CFA induced arthritis in rats by buchnania lanzan Open
Buchanania lanzan spreng commonly known as Char, Charoli is a tree 12-15 mt high, with straight trunk, belonging to family from Anacardiaceae. An herb known as priyal is a drug of the ayurveda and the unani system of medicine. It is known …
View article: Design, Development, Formulation, and Evaluation of Gastro retentive Floating Tablet for Anti-diabetic Agent
Design, Development, Formulation, and Evaluation of Gastro retentive Floating Tablet for Anti-diabetic Agent Open
The main aim of the research was to persist the gastric residence time of vildagliptin by designing its gastro-retentive tablet as well as to study the effect of different polymers on its release rate using 23 randomized full factorial des…
View article: Assessment of Prescription Pattern of Drugs Prescribed in the Outpatient Department of a Private Orthopedic Hospital – A Cross-sectional Study
Assessment of Prescription Pattern of Drugs Prescribed in the Outpatient Department of a Private Orthopedic Hospital – A Cross-sectional Study Open
Background: Drug utilization research (DUR) is vital in the health sector as it offers insight into the efficacy of drug use. The findings of DUR studies can help set goals for the rational use of drugs and health-care funds distribution. …
View article: A Randomized, Parallel Study to Compare Efficacy & Safety of Streptokinase vs Tenecteplase when Given in Correct Timelines in Patients of ST-Elevation Myocardial Infarction (STEMI)
A Randomized, Parallel Study to Compare Efficacy & Safety of Streptokinase vs Tenecteplase when Given in Correct Timelines in Patients of ST-Elevation Myocardial Infarction (STEMI) Open