Satish K. Singh
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View article: Enhanced visualization of colonic polyps using a fluorophore-conjugated claudin-1 antibody in a CPC-APC mouse model
Enhanced visualization of colonic polyps using a fluorophore-conjugated claudin-1 antibody in a CPC-APC mouse model Open
View article: TriGgeR mechanisms of Antarctic ice sheet INStability across the Plio-pLeistocene trAnsitIoN - GRAINSPLAIN project
TriGgeR mechanisms of Antarctic ice sheet INStability across the Plio-pLeistocene trAnsitIoN - GRAINSPLAIN project Open
Growing evidence suggests that portions of the Antarctic Ice Sheet (AIS) could cross a tipping point over the next decades due to global warming. The Mid-Pliocene Warm Period (mPWP, 3.3-3 Ma, +2°C) is regarded as one possible geologic…
View article: Specific Targeting and Labeling of Colonic Polyps in CPC-APC Mice with Mucin 5AC Fluorescent Antibodies: A Model for Detection of Early Colon Cancer
Specific Targeting and Labeling of Colonic Polyps in CPC-APC Mice with Mucin 5AC Fluorescent Antibodies: A Model for Detection of Early Colon Cancer Open
Poor visualization of polyps can limit colorectal cancer screening. Fluorescent antibodies to mucin5AC (MUC5AC), a glycoprotein upregulated in adenomas and colorectal cancer, could improve screening colonoscopy polyp detection rate. Adenom…
View article: Emergency Department Point-of-Care Tests during Cardiopulmonary Resuscitation to Predict Cardiac Arrest Outcomes
Emergency Department Point-of-Care Tests during Cardiopulmonary Resuscitation to Predict Cardiac Arrest Outcomes Open
Introduction: This study evaluated the role of point-of-care tests (POCT) such as blood lactate, anion gap (AG), base deficit, pH, N-terminal pro B-type natriuretic peptide (NT-proBNP), and troponin as the predictors of cardiac arrest outc…
View article: Physio-chemical characterization of sewage sludge generated from sewage treatment plant at Varanasi, in relation to nutrients and heavy metals for agriculture use
Physio-chemical characterization of sewage sludge generated from sewage treatment plant at Varanasi, in relation to nutrients and heavy metals for agriculture use Open
Large amount of sewage sludge is generated during waste water treatment at sewage treatment plant (STP), as a result of the sedimentation and suspension of particles. The safe disposal and management of this concentrated sewage sludge pose…
View article: Delphi Initiative for Early-Onset Colorectal Cancer (DIRECt) International Management Guidelines
Delphi Initiative for Early-Onset Colorectal Cancer (DIRECt) International Management Guidelines Open
View article: Bag of Visual Words (BoVW) with Deep Features -- Patch Classification Model for Limited Dataset of Breast Tumours
Bag of Visual Words (BoVW) with Deep Features -- Patch Classification Model for Limited Dataset of Breast Tumours Open
Currently, the computational complexity limits the training of high resolution gigapixel images using Convolutional Neural Networks. Therefore, such images are divided into patches or tiles. Since, these high resolution patches are encoded…
View article: Regulation of Glucose Insulinotropic Peptide and Intestinal Glucose Transporters in the Diet-Induced Obese Mouse
Regulation of Glucose Insulinotropic Peptide and Intestinal Glucose Transporters in the Diet-Induced Obese Mouse Open
Our recent studies have shown that glucose-dependent insulinotropic polypeptide (GIP), but not glucagon-like peptide 1 (GLP-1), augments Na-glucose transporter 1- (SGLT1-) mediated glucose absorption in mouse jejunum. Na-dependent glucose …
View article: MiR-592 activates the mTOR kinase, ERK1/ERK2 kinase signaling and imparts neuronal differentiation signature characteristic of Group 4 medulloblastoma
MiR-592 activates the mTOR kinase, ERK1/ERK2 kinase signaling and imparts neuronal differentiation signature characteristic of Group 4 medulloblastoma Open
View article: A Novel Deep Learning Method for Thermal to Annotated Thermal-Optical Fused Images
A Novel Deep Learning Method for Thermal to Annotated Thermal-Optical Fused Images Open
Thermal Images profile the passive radiation of objects and capture them in grayscale images. Such images have a very different distribution of data compared to optical colored images. We present here a work that produces a grayscale therm…
View article: A Simple Mutual Information based Registration Method for Thermal-Optical Image Pairs applied on a Novel Dataset
A Simple Mutual Information based Registration Method for Thermal-Optical Image Pairs applied on a Novel Dataset Open
While thermal optical registered datasets are becoming widely available, most of these works are based on image pairs which are pre-registered. However, thermal imagers where these images are registered by default are quite expensive. We p…
View article: Advanced endoscopic imaging for detecting and guiding therapy of early neoplasias of the esophagus
Advanced endoscopic imaging for detecting and guiding therapy of early neoplasias of the esophagus Open
Esophageal cancers, largely adenocarcinoma in Western countries and squamous cell cancer in Asia, present a significant burden of disease and remain one of the most lethal of cancers. Key to improving survival is the development and adopti…
View article: REAPPRAISAL OF RISK FACTORS FOR LUNGRADS 4 IN A RACIALLY DIVERSE SCREENING COHORT
REAPPRAISAL OF RISK FACTORS FOR LUNGRADS 4 IN A RACIALLY DIVERSE SCREENING COHORT Open
View article: Correction to: In Vivo Stability of Therapeutic Proteins
Correction to: In Vivo Stability of Therapeutic Proteins Open
View article: Freezing of Biologicals Revisited: Scale, Stability, Excipients, and Degradation Stresses
Freezing of Biologicals Revisited: Scale, Stability, Excipients, and Degradation Stresses Open
Although many biotech products are successfully stored in the frozen state, there are cases of degradation of biologicals during freeze storage. These examples are discussed in the Perspective to emphasize the fact that stability of frozen…
View article: Mo2041 – Artificial Intelligence Augments Real-Time Histology of Colon Polyps Using Combined-Modality Narrow Band Image Classification and Elastic-Scattering Spectroscopy
Mo2041 – Artificial Intelligence Augments Real-Time Histology of Colon Polyps Using Combined-Modality Narrow Band Image Classification and Elastic-Scattering Spectroscopy Open
View article: Volumetric laser endomicroscopy and its application to Barrett's esophagus: results from a 1,000 patient registry
Volumetric laser endomicroscopy and its application to Barrett's esophagus: results from a 1,000 patient registry Open
SUMMARY Volumetric laser endomicroscopy (VLE) uses optical coherence tomography (OCT) for real-time, microscopic cross-sectional imaging. A US-based multi-center registry was constructed to prospectively collect data on patients undergoing…
View article: Precision Medicine for CRC Patients in the Veteran Population: State-of-the-Art, Challenges and Research Directions
Precision Medicine for CRC Patients in the Veteran Population: State-of-the-Art, Challenges and Research Directions Open
View article: Use of probe‐based confocal laser endomicroscopy (pCLE) in gastrointestinal applications. A consensus report based on clinical evidence
Use of probe‐based confocal laser endomicroscopy (pCLE) in gastrointestinal applications. A consensus report based on clinical evidence Open
Background Probe‐based confocal laser endomicroscopy (pCLE) provides microscopic imaging during an endoscopic procedure. Its introduction as a standard modality in gastroenterology has brought significant progress in management strategies,…