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View article: Revascularization Treatment of Basilar Artery Occlusion in Patients with Mild‐to‐Moderate Severe Stroke
Revascularization Treatment of Basilar Artery Occlusion in Patients with Mild‐to‐Moderate Severe Stroke Open
BACKGROUND The benefit of endovascular thrombectomy (EVT) in patients with basilar artery occlusion and severe neurological deficits is well established. However, its effectiveness in those with mild‐to‐moderate deficits remains uncertain.…
View article: Safety of endovascular therapy in ischemic stroke patients ⩾90 years: A cohort study from the EVA-TRISP collaboration
Safety of endovascular therapy in ischemic stroke patients ⩾90 years: A cohort study from the EVA-TRISP collaboration Open
Introduction: Data on safety of endovascular therapy (EVT) in the very elderly are scarce. Using data from a large prospective EVT registry, we aimed at providing better evidence for EVT decision-making in patients aged 90 years and older.…
View article: Intravenous Thrombolysis in Patients With Recent Intake of Direct Oral Anticoagulants: A Target Trial Analysis and Comparison With Reversal Agent Use
Intravenous Thrombolysis in Patients With Recent Intake of Direct Oral Anticoagulants: A Target Trial Analysis and Comparison With Reversal Agent Use Open
BACKGROUND: Intravenous thrombolysis (IVT) in patients with recent ingestion of direct oral anticoagulants (DOACs) is a frequent challenge and remains controversial. The benefit of DOAC reversal before IVT is uncertain. METHODS: Using targ…
View article: Sex differences in outcomes after endovascular therapy with prior antiplatelet use: A study from the EVA-TRISP registry
Sex differences in outcomes after endovascular therapy with prior antiplatelet use: A study from the EVA-TRISP registry Open
Introduction: This study assessed sex differences in outcomes after mechanical thrombectomy (MT) with prior antiplatelet use using the EVA-TRISP multinational registry. Patients and methods: A cohort of consecutive patients (2015–2023) tre…
View article: Safety of intravenous thrombolysis in stroke mimics: A 15-year experience
Safety of intravenous thrombolysis in stroke mimics: A 15-year experience Open
Introduction: The necessity of timely administration of intravenous thrombolysis (IVT) in the treatment of acute ischemic stroke may result in its administration in conditions that mimic stroke with their clinical presentation ("stroke mim…
View article: Intravenous thrombolysis in young adults with ischemic stroke: A cohort study from the international TRISP collaboration
Intravenous thrombolysis in young adults with ischemic stroke: A cohort study from the international TRISP collaboration Open
Background and aims: Previous observational data indicate that young adults treated with intravenous thrombolysis (IVT) for acute ischemic stroke have more favorable outcomes and less complications when compared to older adults. Given the …
View article: Endovascular therapy in patients with acute intracranial non-terminal internal carotid artery occlusion (ICA-I)
Endovascular therapy in patients with acute intracranial non-terminal internal carotid artery occlusion (ICA-I) Open
Background: Acute intracranial occlusion of the internal carotid artery (ICA) can be distinguished into (a) occlusion of the terminal ICA, involving the proximal segments of the middle or anterior cerebral artery (ICA-L/-T) and (b) non-ter…
View article: Endovascular treatment in patients with acute ischemic stroke presenting beyond 6 h after symptom onset: An international multicenter cohort study of the EVA-TRISP collaboration
Endovascular treatment in patients with acute ischemic stroke presenting beyond 6 h after symptom onset: An international multicenter cohort study of the EVA-TRISP collaboration Open
Introduction: After positive findings in clinical trials the time window for endovascular thrombectomy (EVT) for patients with an acute ischemic stroke has been expanded up to 24 h from symptom onset or last seen well (LSW). We aimed to co…
View article: Corrigendum: Tandem occlusions involving the internal carotid and anterior cerebral arteries—A rare form of stroke: results from the multicenter EVATRISP collaboration study
Corrigendum: Tandem occlusions involving the internal carotid and anterior cerebral arteries—A rare form of stroke: results from the multicenter EVATRISP collaboration study Open
[This corrects the article DOI: 10.3389/fneur.2022.1024891.].
View article: P11.69.B INTRAVENOUS THROMBOLYSIS WITH OR WITHOUT ENDOVASCULAR TREATMENT FOR SUSPECTED ISCHEMIC STROKE IN PATIENTS WITH INTRACRANIAL TUMORS
P11.69.B INTRAVENOUS THROMBOLYSIS WITH OR WITHOUT ENDOVASCULAR TREATMENT FOR SUSPECTED ISCHEMIC STROKE IN PATIENTS WITH INTRACRANIAL TUMORS Open
BACKGROUND: AND OBJECTIVES Intravenous thrombolysis (IVT) for suspected ischemic stroke in patients with intracranial neoplasms is off-label. However, data on risks of intracranial hemorrhage (ICH) is scarce. METHODS In a multicenter regis…
View article: IV Thrombolysis With or Without Endovascular Treatment for Suspected Ischemic Stroke in Patients With Intracranial Tumors
IV Thrombolysis With or Without Endovascular Treatment for Suspected Ischemic Stroke in Patients With Intracranial Tumors Open
In our dataset from routine clinical care, we provide insights on the safety of IVT for suspected ischemic stroke in patients with intracranial tumors, a population that is commonly withheld thrombolysis in clinical practice and prospectiv…
View article: Recanalization Therapies for Large Vessel Occlusion Due to Cervical Artery Dissection: A Cohort Study of the EVA-TRISP Collaboration
Recanalization Therapies for Large Vessel Occlusion Due to Cervical Artery Dissection: A Cohort Study of the EVA-TRISP Collaboration Open
Background and Purpose This study aimed to investigate the effect of endovascular treatment (EVT, with or without intravenous thrombolysis [IVT]) versus IVT alone on outcomes in patients with acute ischemic stroke (AIS) and intracranial la…
View article: Intravenous Thrombolysis 4.5–9 Hours After Stroke Onset: A Cohort Study from the <scp>TRISP</scp> Collaboration
Intravenous Thrombolysis 4.5–9 Hours After Stroke Onset: A Cohort Study from the <span>TRISP</span> Collaboration Open
Objective To investigate the safety and effectiveness of intravenous thrombolysis (IVT) >4.5–9 hours after stroke onset, and the relevance of advanced neuroimaging for patient selection. Methods Prospective multicenter cohort study from th…
View article: Impact of the COVID-19 pandemic on pre-hospital and in-hospital time-dependent performance measures of treatment of patients with acute ischemic stroke - experience of a tertiary healthcare center
Impact of the COVID-19 pandemic on pre-hospital and in-hospital time-dependent performance measures of treatment of patients with acute ischemic stroke - experience of a tertiary healthcare center Open
Introduction/Objective. The outbreak of the COVID-19 pandemic has posed major challenges to the process of urgent care of patients with acute ischemic stroke (AIS) that requires optimal and well-coordinated pre- and in-hospital chains in o…
View article: Tandem occlusions involving the internal carotid and anterior cerebral arteries—A rare form of stroke: Results from the multicenter EVATRISP collaboration study
Tandem occlusions involving the internal carotid and anterior cerebral arteries—A rare form of stroke: Results from the multicenter EVATRISP collaboration study Open
Background Patients with stroke secondary to isolated anterior cerebral artery (ACA) occlusions have poor outcomes. Whether tandem occlusions (TO) of the extracranial internal carotid (ICA) and the ACA carry even worse outcomes that remain…
View article: Intravenous Thrombolysis in Patients With Ischemic Stroke Aged ≥90 Years: A Cohort Study From the TRISP Collaboration
Intravenous Thrombolysis in Patients With Ischemic Stroke Aged ≥90 Years: A Cohort Study From the TRISP Collaboration Open
Background: The probability to receive intravenous thrombolysis (IVT) for treatment of acute ischemic stroke declines with increasing age and is consequently the lowest in very elderly patients. Safety concerns likely influence individual …
View article: Thrombolysis in stroke patients with elevated inflammatory markers
Thrombolysis in stroke patients with elevated inflammatory markers Open
View article: EndoVAscular treatment and ThRombolysis for Ischemic Stroke Patients (EVA-TRISP) registry: basis and methodology of a pan-European prospective ischaemic stroke revascularisation treatment registry
EndoVAscular treatment and ThRombolysis for Ischemic Stroke Patients (EVA-TRISP) registry: basis and methodology of a pan-European prospective ischaemic stroke revascularisation treatment registry Open
Purpose The Thrombolysis in Ischemic Stroke Patients (TRISP) collaboration was a concerted effort initiated in 2010 with the purpose to address relevant research questions about the effectiveness and safety of intravenous thrombolysis (IVT…
View article: Maintenance of Acute Stroke Care Service During the COVID-19 Pandemic Lockdown
Maintenance of Acute Stroke Care Service During the COVID-19 Pandemic Lockdown Open
Background and Purpose: Timely reperfusion is an important goal in treatment of eligible patients with acute ischemic stroke. However, during the coronavirus disease 2019 (COVID-19) pandemic, prehospital and in-hospital emergency procedure…
View article: Acute stroke care during the COVID‐19 pandemic
Acute stroke care during the COVID‐19 pandemic Open
The outbreak of the coronavirus (COVID-19) pandemic has led to a global public health crisis, with a significant impact on different aspects of healthcare performance including acute stroke management. The introduction of various restricti…
View article: Prior Dual Antiplatelet Therapy and Thrombolysis in Acute Stroke
Prior Dual Antiplatelet Therapy and Thrombolysis in Acute Stroke Open
View article: Association of prestroke metformin use, stroke severity, and thrombolysis outcome
Association of prestroke metformin use, stroke severity, and thrombolysis outcome Open
Patients with stroke and diabetes on treatment with MET receiving IVT had less severe strokes on admission and a better functional outcome at 3 months. This suggests a protective effect of MET resulting in less severe strokes as well as be…
View article: Effect of haemoglobin levels on outcome in intravenous thrombolysis-treated stroke patients
Effect of haemoglobin levels on outcome in intravenous thrombolysis-treated stroke patients Open
Introduction Alterations in haemoglobin levels are frequent in stroke patients. The prognostic meaning of anaemia and polyglobulia on outcomes in patients treated with intravenous thrombolysis is ambiguous. Patients and methods In this pro…
View article: Cohort profile: Thrombolysis in Ischemic Stroke Patients (TRISP): a multicentre research collaboration
Cohort profile: Thrombolysis in Ischemic Stroke Patients (TRISP): a multicentre research collaboration Open
Purpose The ThRombolysis in Ischemic Stroke Patients (TRISP) collaboration aims to address clinically relevant questions about safety and outcomes of intravenous thrombolysis (IVT) and endovascular thrombectomy. The findings can provide ob…
View article: Sex Differences and Functional Outcome After Intravenous Thrombolysis
Sex Differences and Functional Outcome After Intravenous Thrombolysis Open
Background and Purpose— Women have a worse outcome after stroke compared with men, although in intravenous thrombolysis (IVT)–treated patients, women seem to benefit more. Besides sex differences, age has also a possible effect on function…
View article: Intravenous Thrombolysis in Patients Dependent on the Daily Help of Others Before Stroke
Intravenous Thrombolysis in Patients Dependent on the Daily Help of Others Before Stroke Open
Background and Purpose— We compared outcome and complications in patients with stroke treated with intravenous thrombolysis (IVT) who could not live alone without help of another person before stroke (dependent patients) versus independent…
View article: Recanalization Therapies in Acute Ischemic Stroke Patients
Recanalization Therapies in Acute Ischemic Stroke Patients Open
Background— We explored the safety of intravenous thrombolysis (IVT) or intra-arterial treatment (IAT) in patients with ischemic stroke on non-vitamin K antagonist oral anticoagulants (NOACs, last intake <48 hours) in comparison with patie…