Viswanathan Mohan
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View article: Response to: Letter to the Editor Regarding ‘Profile of Metabolic Dysfunction-Associated Steatotic Liver Disease: Mapping Across Different Indian Populations (MAP Study)’
Response to: Letter to the Editor Regarding ‘Profile of Metabolic Dysfunction-Associated Steatotic Liver Disease: Mapping Across Different Indian Populations (MAP Study)’ Open
View article: Nutritional composition, iron bio-accessibility of selected foxtail and finger millet varieties and their products
Nutritional composition, iron bio-accessibility of selected foxtail and finger millet varieties and their products Open
Foods with superior bioavailable nutrients can improve diet quality. Millets are a good source of protein, dietary fibre, iron, calcium, B-complex vitamins, and phytochemicals. In the present study, the nutritional profile and in vitro iro…
View article: Does health insurance coverage improve cardiometabolic risk factor levels? Quasi-experimental evidence from India
Does health insurance coverage improve cardiometabolic risk factor levels? Quasi-experimental evidence from India Open
Health insurance coverage was associated with better cardiometabolic risk profiles and health status, largely mediated by increased healthcare utilization. Expanding insurance coverage to include outpatient chronic care services should be …
View article: Immunoendocrine network under conditions of diabetes-filariasis co-morbidity DMLF6
Immunoendocrine network under conditions of diabetes-filariasis co-morbidity DMLF6 Open
View article: Efficacy and Safety of Once-Weekly Insulin Icodec in Indian Participants with Diabetes: Results from ONWARDS 1, 4, and 6 Studies
Efficacy and Safety of Once-Weekly Insulin Icodec in Indian Participants with Diabetes: Results from ONWARDS 1, 4, and 6 Studies Open
View article: Multimorbidity among adult Indians –prevaLence, incidence, risk fActors and economic burdeN: the MILAN cohort study protocol
Multimorbidity among adult Indians –prevaLence, incidence, risk fActors and economic burdeN: the MILAN cohort study protocol Open
Introduction Multimorbidity or multiple long-term conditions (MLTCs) are defined as the coexistence of two or more chronic conditions in an individual. With increased longevity and the rising burden of chronic non-communicable diseases (NC…
View article: Evaluating a digital intervention for prevention of type 2 diabetes: protocol for a cluster-randomised controlled trial in urban and rural India
Evaluating a digital intervention for prevention of type 2 diabetes: protocol for a cluster-randomised controlled trial in urban and rural India Open
Background The rising prevalence of diabetes, particularly in low- and middle-income countries, highlights an urgent need for innovative approaches to prevention. India faces a growing burden of type 2 diabetes (T2D), placing considerable …
View article: Further Perspectives on Predictive Modeling for Diabetes Subtypes Classification in India
Further Perspectives on Predictive Modeling for Diabetes Subtypes Classification in India Open
View article: Optimizing Type 2 Diabetes Management: The Efficacy and Safety of Gliclazide in Clinical Practice
Optimizing Type 2 Diabetes Management: The Efficacy and Safety of Gliclazide in Clinical Practice Open
Sulfonylureas have been used in type 2 diabetes (T2D) management for over six decades, particularly when the use of metformin alone is insufficient. Despite their efficacy, concerns about hypoglycemia and cardiovascular risks have limited …
View article: Dietary profiles and associated metabolic risk factors in India from the ICMR–INDIAB survey-21
Dietary profiles and associated metabolic risk factors in India from the ICMR–INDIAB survey-21 Open
View article: Exome-wide association study in 54,698 south Asians identifies novel type 2 diabetes associations with <i>RNF19A</i>, <i>HNF4A</i>, and dissects role of coding variants in GP2 and <i>CDKAL1</i>
Exome-wide association study in 54,698 south Asians identifies novel type 2 diabetes associations with <i>RNF19A</i>, <i>HNF4A</i>, and dissects role of coding variants in GP2 and <i>CDKAL1</i> Open
Type 2 diabetes (T2D) disproportionately affects individuals of South Asian ancestry, yet the underlying genetic aetiology remains poorly understood and in genetic studies these populations remain underrepresented. We conducted an exome-wi…
View article: XBP1 expression in pancreatic islet cells is associated with poor glycaemic control especially in young non-obese onset diabetes across ancestries
XBP1 expression in pancreatic islet cells is associated with poor glycaemic control especially in young non-obese onset diabetes across ancestries Open
Background Individuals of South and East Asian ancestry have a higher risk of type 2 diabetes, often driven by insulin deficiency due to impaired beta-cell function. The transcription factor XBP1 supports beta-cell survival by reducing cel…
View article: MetaEmbed: Scaling Multimodal Retrieval at Test-Time with Flexible Late Interaction
MetaEmbed: Scaling Multimodal Retrieval at Test-Time with Flexible Late Interaction Open
Universal multimodal embedding models have achieved great success in capturing semantic relevance between queries and candidates. However, current methods either condense queries and candidates into a single vector, potentially limiting th…
View article: Integrative proteomic analysis provides novel therapeutic insights for etiological subtypes of diabetes
Integrative proteomic analysis provides novel therapeutic insights for etiological subtypes of diabetes Open
Aims Type 2 diabetes (T2D) is a highly heterogeneous disease characterised by subtypes with variations in aetiology, disease progression, and risk of complications. However, potential drug targets for these subtypes have not been explored.…
View article: Comparison of Pregnancy Outcomes between Treated Early Gestational Diabetes Mellitus (EGDM) and Late Gestational Diabetes Mellitus (LGDM)
Comparison of Pregnancy Outcomes between Treated Early Gestational Diabetes Mellitus (EGDM) and Late Gestational Diabetes Mellitus (LGDM) Open
Introduction: Early gestational diabetes mellitus (EGDM) is a relatively new entity, and there is a lack of clarity regarding treatment. This study was carried out to compare the maternal and neonatal outcomes between treated EGDM and late…
View article: Prediabetes: the best opportunity to reach remission
Prediabetes: the best opportunity to reach remission Open
View article: The Influence of Depression, Positive Health Behaviors, and Weight Status on Glycated Hemoglobin: A Sequential Mediation Analysis of the INDEPENDENT Trial
The Influence of Depression, Positive Health Behaviors, and Weight Status on Glycated Hemoglobin: A Sequential Mediation Analysis of the INDEPENDENT Trial Open
View article: Development and Validation of DIANA (Diabetes Novel Subgroup Assessment tool): A web-based precision medicine tool to determine type 2 diabetes endotype membership and predict individuals at risk of microvascular disease
Development and Validation of DIANA (Diabetes Novel Subgroup Assessment tool): A web-based precision medicine tool to determine type 2 diabetes endotype membership and predict individuals at risk of microvascular disease Open
Background Previous research has identified four distinct endotypes of type 2 diabetes in Asian Indians, which include Severe Insulin Deficient Diabetes (SIDD), Combined Insulin Resistant and Deficient Diabetes (CIRDD), Insulin Resistance …
View article: The Use of Continuous Glucose Monitoring in Comparison to Self-Monitoring of Blood Glucose in Gestational Diabetes: A Systematic Review
The Use of Continuous Glucose Monitoring in Comparison to Self-Monitoring of Blood Glucose in Gestational Diabetes: A Systematic Review Open
Background: Continuous glucose monitoring (CGM) has emerged as an important tool for managing gestational diabetes mellitus (GDM), offering real-time glucose data and the potential for improved glycemic control. Unlike traditional self-mon…
View article: The burden of cardiovascular events according to cardiovascular risk profile in adults from high-income, middle-income, and low-income countries (PURE): a cohort study
The burden of cardiovascular events according to cardiovascular risk profile in adults from high-income, middle-income, and low-income countries (PURE): a cohort study Open
The funding bodies are listed in the appendix (p 29).
View article: Neurosteroid Levels in Pregnancy and Its Implications for Mental Health: A Literature Review
Neurosteroid Levels in Pregnancy and Its Implications for Mental Health: A Literature Review Open
Background Perinatal mood disorders are being increasingly recognised and may have deleterious outcomes for the mother and offspring, underlining the importance of understanding their pathophysiology. Neurosteroids can alter the excitabili…
View article: Diabetic kidney disease: epidemiology to epigenetics and beyond
Diabetic kidney disease: epidemiology to epigenetics and beyond Open
View article: Effectiveness of Glipizide and Glipizide Plus Metformin Formulation among Asian Indians with Type 2 Diabetes: a Real‐World, Retrospective Electronic Medical Record Analysis
Effectiveness of Glipizide and Glipizide Plus Metformin Formulation among Asian Indians with Type 2 Diabetes: a Real‐World, Retrospective Electronic Medical Record Analysis Open
View article: Prevalence of Hepatic Steatosis and Fibrosis in Asian Indian Individuals with Type 2 Diabetes
Prevalence of Hepatic Steatosis and Fibrosis in Asian Indian Individuals with Type 2 Diabetes Open
More than 75.6% of individuals with T2D have evidence of hepatic steatosis and 28.6% have fibrosis, as indicated by TE (FibroScan). FIB-4, NFS, and APRI have variable sensitivity and specificity for detecting hepatic fibrosis in Asian Indi…
View article: Evaluation of Logistic Regression and Advanced Machine Learning Algorithms to Differentiate between Type 1 and Type 2 Diabetes in India
Evaluation of Logistic Regression and Advanced Machine Learning Algorithms to Differentiate between Type 1 and Type 2 Diabetes in India Open
Aim: We attempted to determine whether machine learning (ML) models outperform logistic regression (LR), a traditional prediction method, in distinguishing type 1 diabetes (T1D) from type 2 diabetes (T2D). Materials and Methods: Utilizing …
View article: Dietary Approaches in Prevention and Management of Diabetes – Potential Advantages and Drawbacks Among Asian Indians with Diabetes
Dietary Approaches in Prevention and Management of Diabetes – Potential Advantages and Drawbacks Among Asian Indians with Diabetes Open
Diabetes is growing in epidemic proportions in many countries, including India, resulting in a significant increase in morbidity and mortality. In India, the reported prevalence of diabetes and prediabetes stands at 11.4% and 15.3%, affect…
View article: Bronze Diabetes in Congenital Dyserythropoietic Anemia Type 2: A Case Report
Bronze Diabetes in Congenital Dyserythropoietic Anemia Type 2: A Case Report Open
Secondary diabetes is caused by endocrine, pancreatic or hereditary disorders or certain medications which affect insulin secretion or action or both. CDA type 2 is a rare hematological diagnosis which can lead to ineffective erythropoiesi…
View article: High prevalence of metabolic obesity in India: The ICMR-INDIAB national study (ICMR-INDIAB-23)
High prevalence of metabolic obesity in India: The ICMR-INDIAB national study (ICMR-INDIAB-23) Open
Background & objectives While obesity usually produces cardio-metabolic dysfunction, some obese individuals are metabolically healthy, and conversely, some nonobese individuals have significant metabolic dysfunction. This study aims to ass…
View article: Subtypes of Type 2 Diabetes and Prediabetes: Mortality and Excess Life Lost in South Asians
Subtypes of Type 2 Diabetes and Prediabetes: Mortality and Excess Life Lost in South Asians Open
Background Current definitions of type 2 diabetes (T2D) and prediabetes do not capture their pathophysiological heterogeneity. We investigated data-driven subtypes of T2D and prediabetes and evaluated their associations with mortality.Meth…
View article: Evaluating the Impact of mySugr® Mobile Health Application on Glycemic Control in People with Diabetes Mellitus in India: A Real-World Data Analysis
Evaluating the Impact of mySugr® Mobile Health Application on Glycemic Control in People with Diabetes Mellitus in India: A Real-World Data Analysis Open
The mySugr® app, used in conjunction with the Accu-Chek® Instant glucose meter, demonstrated improved glycemic control. Future research should focus on larger, diverse samples and long-term evaluations to confirm thes…