Vito S. Hernández
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View article: Kölliker-Fuse/parabrachial complex PACAP - glutamate pathway to the extended amygdala couples rapid autonomic and delayed endocrine responses to acute hypotension
Kölliker-Fuse/parabrachial complex PACAP - glutamate pathway to the extended amygdala couples rapid autonomic and delayed endocrine responses to acute hypotension Open
The calyx of Held is a giant axo-somatic synapse classically confined to the auditory brainstem. We recently identified morphologically similar calyx-like terminals in the extended amygdala (EA) that arise from the ventrolateral parabrachi…
View article: Comprehensive chemoanatomical mapping, and the gonadal regulation, of seven kisspeptin neuronal populations in the mouse brain
Comprehensive chemoanatomical mapping, and the gonadal regulation, of seven kisspeptin neuronal populations in the mouse brain Open
Kisspeptinergic signaling is well‐established as crucial for the regulation of reproduction, but its potential broader role in brain function is less understood. This study investigates the distribution and chemotyping of kisspeptin‐expres…
View article: Kisspeptin fiber and receptor distribution analysis suggests its potential role in central sensorial processing and behavioral state control
Kisspeptin fiber and receptor distribution analysis suggests its potential role in central sensorial processing and behavioral state control Open
Kisspeptin (KP) signaling in the brain is defined by the anatomical distribution of KP‐producing neurons, their fibers, receptors, and connectivity. Technological advances have prompted a re‐evaluation of these chemoanatomical aspects, ori…
View article: Comprehensive chemotyping, and the gonadal regulation, of seven kisspeptinergic neuronal populations in the mouse brain
Comprehensive chemotyping, and the gonadal regulation, of seven kisspeptinergic neuronal populations in the mouse brain Open
Background Kisspeptinergic signaling is well-established as crucial for regulation of reproduction, but its potential broader role in brain function is less understood. This study investigates the distribution and chemotyping of kisspeptin…
View article: Morphological Signatures of Neurogenesis and Neuronal Migration in Hypothalamic Vasopressinergic Magnocellular Nuclei of the Adult Rat
Morphological Signatures of Neurogenesis and Neuronal Migration in Hypothalamic Vasopressinergic Magnocellular Nuclei of the Adult Rat Open
The arginine vasopressin (AVP)-magnocellular neurosecretory system (AVPMNS) in the hypothalamus plays a critical role in homeostatic regulation as well as in allostatic motivational behaviors. However, it remains unclear whether adult neur…
View article: Kisspeptin fiber and receptor distribution analysis suggests its potential role in central sensorial processing and behavioral state control
Kisspeptin fiber and receptor distribution analysis suggests its potential role in central sensorial processing and behavioral state control Open
Background Kisspeptin (KP) signaling in the brain is defined by the anatomical distribution of KP-producing neurons, their fibers, receptors, and connectivity. Technological advances have prompted a re-evaluation of these chemoanatomical a…
View article: Nucleus of the lateral olfactory tract: A hub linking the water homeostasis‐associated <scp>supraoptic nucleus‐arginine vasopressin</scp> circuit and neocortical regions to promote social behavior under osmotic challenge
Nucleus of the lateral olfactory tract: A hub linking the water homeostasis‐associated <span>supraoptic nucleus‐arginine vasopressin</span> circuit and neocortical regions to promote social behavior under osmotic challenge Open
Homeostatic challenges may alter the drive for social interaction. The neural activity that prompts this motivation remains poorly understood. In the present study, we identify direct projections from the hypothalamic supraoptic nucleus to…
View article: Neuropeptides and small-molecule amine transmitters: cooperative signaling in the nervous system
Neuropeptides and small-molecule amine transmitters: cooperative signaling in the nervous system Open
View article: Nucleus of the lateral olfactory tract (NLOT): a hub linking water homeostasis-associated SON-AVP circuit and neocortical regions to promote social behavior under osmotic challenge
Nucleus of the lateral olfactory tract (NLOT): a hub linking water homeostasis-associated SON-AVP circuit and neocortical regions to promote social behavior under osmotic challenge Open
Homeostatic challenges increase the drive for social interaction. The neural activity that prompts this motivation remains poorly understood. Here, we identify direct projections from the hypothalamic supraoptic nucleus (SON) to the cortic…
View article: Vasopressin acts as a synapse organizer in limbic regions by boosting <scp>PSD95</scp> and <scp>GluA1</scp> expression
Vasopressin acts as a synapse organizer in limbic regions by boosting <span>PSD95</span> and <span>GluA1</span> expression Open
Hypothalamic arginine vasopressin (AVP)‐containing magnocellular neurosecretory neurons (AVPMNN) emit collaterals to synaptically innervate limbic regions influencing learning, motivational behaviour, and fear responses. Here, we character…
View article: ACE2 expression in rat brain: Implications for COVID-19 associated neurological manifestations
ACE2 expression in rat brain: Implications for COVID-19 associated neurological manifestations Open
View article: Review for "Vasopressin: An output signal from the suprachiasmatic nucleus to prepare physiology and behavior for the resting phase"
Review for "Vasopressin: An output signal from the suprachiasmatic nucleus to prepare physiology and behavior for the resting phase" Open
View article: Review for "Vasopressin: An output signal from the suprachiasmatic nucleus to prepare physiology and behavior for the resting phase"
Review for "Vasopressin: An output signal from the suprachiasmatic nucleus to prepare physiology and behavior for the resting phase" Open
View article: Review for "Hypothalamic neuropeptides and neurocircuitries in Prader Willi syndrome"
Review for "Hypothalamic neuropeptides and neurocircuitries in Prader Willi syndrome" Open
View article: Author response for "Microglial synaptic pruning on axon initial segment spines of dentate granule cells: Sexually dimorphic effects of early-life stress and consequences for adult fear response"
Author response for "Microglial synaptic pruning on axon initial segment spines of dentate granule cells: Sexually dimorphic effects of early-life stress and consequences for adult fear response" Open
View article: Author response for "Microglial synaptic pruning on axon initial segment spines of dentate granule cells: Sexually dimorphic effects of early-life stress and consequences for adult fear response"
Author response for "Microglial synaptic pruning on axon initial segment spines of dentate granule cells: Sexually dimorphic effects of early-life stress and consequences for adult fear response" Open
View article: Behavioral role of PACAP signaling reflects its selective distribution in glutamatergic and GABAergic neuronal subpopulations
Behavioral role of PACAP signaling reflects its selective distribution in glutamatergic and GABAergic neuronal subpopulations Open
The neuropeptide PACAP, acting as a co-transmitter, increases neuronal excitability, which may enhance anxiety and arousal associated with threat conveyed by multiple sensory modalities. The distribution of neurons expressing PACAP and its…
View article: ACE2 in the second act of COVID‐19 syndrome: Peptide dysregulation and possible correction with oestrogen
ACE2 in the second act of COVID‐19 syndrome: Peptide dysregulation and possible correction with oestrogen Open
Coronavirus disease 2019 (COVID‐19) has become the most critical pandemic of the 21st Century and the most severe since the 1918 influenza pandemic. Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infects the host by binding t…
View article: Review for "Hypothalamic neuropeptides and neurocircuitries in Prader Willi syndrome"
Review for "Hypothalamic neuropeptides and neurocircuitries in Prader Willi syndrome" Open
View article: Tomographic behavior of pneumonia caused by SARS-CoV-2
Tomographic behavior of pneumonia caused by SARS-CoV-2 Open
Knowing the behavior of this type of pneumonia allows becoming familiarized with the characteristic tomographic patterns, in order to aid timely detection and treatment.
View article: Author response: Behavioral role of PACAP signaling reflects its selective distribution in glutamatergic and GABAergic neuronal subpopulations
Author response: Behavioral role of PACAP signaling reflects its selective distribution in glutamatergic and GABAergic neuronal subpopulations Open
Article Figures and data Abstract Introduction Results Discussion Materials and methods Appendix 1 Data availability References Decision letter Author response Article and author information Metrics Abstract The neuropeptide PACAP, acting …
View article: Review for "Neuroendocrine changes in the hypothalamic‐neurohypophysial system in the Wistar audiogenic rat (WAR) strain submitted to audiogenic kindling"
Review for "Neuroendocrine changes in the hypothalamic‐neurohypophysial system in the Wistar audiogenic rat (WAR) strain submitted to audiogenic kindling" Open
View article: Vasopressin acts as a synapse organizer in limbic regions by boosting PSD95 and GluA1 expression
Vasopressin acts as a synapse organizer in limbic regions by boosting PSD95 and GluA1 expression Open
Hypothalamic arginine vasopressin (AVP)-containing magnocellular neurosecretory neurons (AVPMNN) emit collaterals to synaptically innervate limbic regions influencing learning, motivational behaviour, and fear responses. Here, we character…
View article: Analysis and modeling of low frequency local field oscillations in a hippocampus circuit under osmotic challenge: the possible role of arginine vasopressin circuit for hippocampal function
Analysis and modeling of low frequency local field oscillations in a hippocampus circuit under osmotic challenge: the possible role of arginine vasopressin circuit for hippocampal function Open
Electrophysiological time series were taken simultaneously in two locations in the hippocampus of a rat brain previously described as receiving innervation from the osmosensitive vasopressinergic neurons of the hypothalamus. A hyperosmotic…
View article: Analysis and modeling of low frequency local field oscillations in a\n hippocampus circuit under osmotic challenge: the possible role of arginine\n vasopressin circuit for hippocampal function
Analysis and modeling of low frequency local field oscillations in a\n hippocampus circuit under osmotic challenge: the possible role of arginine\n vasopressin circuit for hippocampal function Open
Electrophysiological time series were taken simultaneously in two locations\nin the hippocampus of a rat brain previously described as receiving innervation\nfrom the osmosensitive vasopressinergic neurons of the hypothalamus. A\nhyperosmo…
View article: Microglial synaptic pruning on axon initial segment of dentate granule cells: sexually dimorphic effects on fear response of adult rats subjected to early life stress
Microglial synaptic pruning on axon initial segment of dentate granule cells: sexually dimorphic effects on fear response of adult rats subjected to early life stress Open
Axon initial segments (AIS) of dentate granule cells (GC) in hippocampus exhibit prominent spines during early development that are associated with microglial contacts. Here, we asked if developmental changes in axon initial segment spines…
View article: Comportamiento tomográfico de la neumonía causada por SARS-CoV-2
Comportamiento tomográfico de la neumonía causada por SARS-CoV-2 Open
Background: From the first report of the respiratory disease caused by SARS-Cov-2 towards the end of 2019, in Wuhan, China, to June 8, 2020, 6,931,000 people had been affected in the world, and 113,619 in Mexico, where there is a lack of l…
View article: Behavioral role of PACAP signaling reflects its selective distribution in glutamatergic and GABAergic neuronal subpopulations
Behavioral role of PACAP signaling reflects its selective distribution in glutamatergic and GABAergic neuronal subpopulations Open
The neuropeptide PACAP, acting as a co-transmitter, increases neuronal excitability, which may enhance anxiety and arousal associated with threat conveyed by multiple sensory modalities. The distribution of neurons expressing PACAP and its…
View article: Regulatory peptides and systems biology: A new era of translational and reverse‐translational neuroendocrinology
Regulatory peptides and systems biology: A new era of translational and reverse‐translational neuroendocrinology Open
Recently, there has been a resurgence in regulatory peptide science as a result of three converging trends. The first is the increasing population of the drug pipeline with peptide‐based therapeutics, mainly in, but not restricted to, incr…
View article: A Synaptically Connected Hypothalamic Magnocellular Vasopressin-Locus Coeruleus Neuronal Circuit and Its Plasticity in Response to Emotional and Physiological Stress
A Synaptically Connected Hypothalamic Magnocellular Vasopressin-Locus Coeruleus Neuronal Circuit and Its Plasticity in Response to Emotional and Physiological Stress Open
The locus coeruleus (LC)-norepinephrine (NE) system modulates a range of salient brain functions, including memory and response to stress. The LC-NE system is regulated by neurochemically diverse inputs, including a range of neuropeptides …