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View article: Long-Term Motor and Cognitive Outcome of Deep Brain Stimulation in Patients With Parkinson Disease With a <i>GBA1</i> Pathogenic Variant
Long-Term Motor and Cognitive Outcome of Deep Brain Stimulation in Patients With Parkinson Disease With a <i>GBA1</i> Pathogenic Variant Open
This study provides Class III evidence that DBS does not worsen cognitive function in patients with GBA1-associated PD.
View article: Cerebral Amyloid-β Deposition, Axial Features, and Cognitive Alterations in Patients with Parkinson’s Disease Treated with Bilateral STN-DBS: A Long-Term Cohort Study
Cerebral Amyloid-β Deposition, Axial Features, and Cognitive Alterations in Patients with Parkinson’s Disease Treated with Bilateral STN-DBS: A Long-Term Cohort Study Open
Objectives: Our aim was to evaluate the possible long-term cerebral deposition of amyloid-β in patients with PD treated with subthalamic nucleus deep brain stimulation (STN-DBS) and its possible influence on axial and cognitive variables. …
View article: Cerebral Amyloid-β Deposition, Axial Features and Cognitive Alterations in Parkinson’s Disease Patients Treated with Bilateral STN-DBS: A Long-term Cohort Study
Cerebral Amyloid-β Deposition, Axial Features and Cognitive Alterations in Parkinson’s Disease Patients Treated with Bilateral STN-DBS: A Long-term Cohort Study Open
Objectives: To evaluate the possible long-term cerebral deposition of amyloid-β in PD patients treated with subthalamic nucleus deep brain stimulation (STN-DBS) and its possible influence on axial and cognitive variables. Methods: Consecut…
View article: Amelioration of Focal Hand Dystonia via Low‐Frequency Repetitive Somatosensory Stimulation
Amelioration of Focal Hand Dystonia via Low‐Frequency Repetitive Somatosensory Stimulation Open
Background Dystonia presents a growing concern based on evolving prevalence insights. Previous research found that, in cervical dystonia, high‐frequency repetitive somatosensory stimulation (RSS; HF‐RSS) applied on digital nerves paradoxic…
View article: Thalamic ventral-Oralis complex/rostral zona incerta deep brain stimulation for midline tremor
Thalamic ventral-Oralis complex/rostral zona incerta deep brain stimulation for midline tremor Open
Background Midline Tremor is defined as an isolated or combined tremor that affects the neck, trunk, jaw, tongue, and/or voice and could be part of Essential Tremor (ET), or dystonic tremor. The clinical efficacy of deep brain stimulation …
View article: Longitudinal Neuropsychological Assessment of Symptomatic Edema after Subthalamic Nucleus Deep Brain Stimulation Surgery: A Case Series Study
Longitudinal Neuropsychological Assessment of Symptomatic Edema after Subthalamic Nucleus Deep Brain Stimulation Surgery: A Case Series Study Open
Severe non-infectious or non-haemorrhagic brain edema surrounding the electrode represents a rare complication of subthalamic nucleus deep brain stimulation (STN-DBS) surgery. The aim of this study is to report three patients with advanced…
View article: Freezing of Gait in Parkinson’s Disease Patients Treated with Bilateral Subthalamic Nucleus Deep Brain Stimulation: A Long-Term Overview
Freezing of Gait in Parkinson’s Disease Patients Treated with Bilateral Subthalamic Nucleus Deep Brain Stimulation: A Long-Term Overview Open
Bilateral subthalamic nucleus deep brain stimulation (STN-DBS) is an effective treatment in advanced Parkinson’s Disease (PD). However, the effects of STN-DBS on freezing of gait (FOG) are still debated, particularly in the long-term follo…
View article: Development of Parkinsonism in a Patient with Central Pontine Myelinolysis
Development of Parkinsonism in a Patient with Central Pontine Myelinolysis Open
Osmotic demyelination syndrome (ODS) is caused by damage to the pons myelin sheath and nerve cells. Although the pathophysiological mechanism responsible for the damage is not yet fully understood, it is currently believed that osmotic-typ…
View article: Needs and Perceptions of Patients With Dystonia During the COVID-19 Pandemic: A Qualitative Framework Analysis of Survey Responses From Italy
Needs and Perceptions of Patients With Dystonia During the COVID-19 Pandemic: A Qualitative Framework Analysis of Survey Responses From Italy Open
Introduction: The COVID-19 pandemic and its countermeasures have created changes in both life and healthcare. With the prioritization of COVID-19-related management, the risks and experiences of patients suffering from rare conditions, suc…
View article: Myasthenia Gravis crossing Parkinson’s disease: a 20 year study from single Italian center
Myasthenia Gravis crossing Parkinson’s disease: a 20 year study from single Italian center Open
The concomitant diagnosis of Parkinson’s disease (PD) and Myasthenia Gravis (MG) is rare. The aim of the study was to report our experience of patients with both diagnoses. We performed a retrospective analysis of patients with MG and PD, …
View article: Ataxia-Myoclonus Syndrome in Patients with SARS-CoV-2 Infection
Ataxia-Myoclonus Syndrome in Patients with SARS-CoV-2 Infection Open
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View article: Parkinson's disease patients' needs during the COVID‐19 pandemic in a red zone: A framework analysis of open‐ended survey questions
Parkinson's disease patients' needs during the COVID‐19 pandemic in a red zone: A framework analysis of open‐ended survey questions Open
Background and purpose During the first phase of the COVID‐19 pandemic, a lockdown was imposed in Italy. The aim of this study was to investigate the perceptions, feelings and unmet needs of Parkinson's disease (PD) patients who experience…
View article: Ataxia with Oculomotor Apraxia Type 1—New Mutation, Characteristic Phenotype
Ataxia with Oculomotor Apraxia Type 1—New Mutation, Characteristic Phenotype Open
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View article: Endotoxemic shock from urinary calculus dog
Endotoxemic shock from urinary calculus dog Open
This study aims to present a case of a dog of the Bichon Frizé breed, male that arrived on the 06/08/2015 at Provet - Moema Pathology Service for a necropsy. According to the history provided by the owner, four days before the death of the…
View article: Levodopa/Carbidopa Intestinal Gel Infusion Therapy: Focus on Gait and Balance
Levodopa/Carbidopa Intestinal Gel Infusion Therapy: Focus on Gait and Balance Open
Background Gait and balance disorders in advanced Parkinson's disease (aPD) heavily impact the disease burden. In this prospective observational open‐label study, our aim was to evaluate the effectiveness of levodopa/carbidopa intestinal g…