Vittorio Scoppola
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View article: Antibody response after pneumococcal vaccination in a large cohort of Italian children and adolescents with Down syndrome
Antibody response after pneumococcal vaccination in a large cohort of Italian children and adolescents with Down syndrome Open
Introduction: Pneumococcal vaccination has significantly decreased the burden of invasive pneumococcal disease in the general population, however studies on effectiveness in Down syndrome (DS) are heterogeneous. In this cross-sectional stu…
View article: Lifestyle Intervention Improves Metabolic Dysfunction-Associated Steatotic Liver Disease in Children with Down Syndrome
Lifestyle Intervention Improves Metabolic Dysfunction-Associated Steatotic Liver Disease in Children with Down Syndrome Open
Background/Objectives: We evaluated the efficacy of a good lifestyle intervention on the severity of metabolic dysfunction-associated steatotic liver disease (MASLD) in children with Down syndrome (DS). Methods: This retrospective longitud…
View article: Combination Treatment with Hydroxytyrosol and Vitamin E Improves NAFLD-Related Fibrosis
Combination Treatment with Hydroxytyrosol and Vitamin E Improves NAFLD-Related Fibrosis Open
Non-alcoholic fatty liver disease (NAFLD)-related liver fibrosis results in the encapsulation of injured liver parenchyma by a collagenous scar mainly imputable to hepatic stellate cells’ activation. Approved pharmacological treatments aga…
View article: Sleep and behavioral problems in preschool-age children with Down syndrome
Sleep and behavioral problems in preschool-age children with Down syndrome Open
Sleep is a major concern, especially in people with Down Syndrome (DS). Beyond Obstructive Sleep Apnea, a number of other sleep difficulties have been reported in children with DS, such as delayed sleep onset, night-time awakenings, and ea…
View article: Safety and Long-Term Immunogenicity of BNT162b2 Vaccine in Individuals with Down Syndrome
Safety and Long-Term Immunogenicity of BNT162b2 Vaccine in Individuals with Down Syndrome Open
We aimed to evaluate the safety and immunogenicity of the BNT162b2 vaccine in young people with Down syndrome (DS), and to compare their humoral immune response with those of the healthy controls (HC). Individuals with DS and HC received t…