Savita Jadhav
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View article: Impact of Pre-Existing Urinary Antimicrobial Agents on Culture Yield, Diagnostic Accuracy, and the Detection of Significant Bacteriuria in Community-Acquired Urinary Tract Infections
Impact of Pre-Existing Urinary Antimicrobial Agents on Culture Yield, Diagnostic Accuracy, and the Detection of Significant Bacteriuria in Community-Acquired Urinary Tract Infections Open
The presence of pre-existing ABS in urine significantly alters microbial culture outcomes, leading to reduced detection of common uropathogens and an increased likelihood of false-negative or insignificant culture results. Additionally, pr…
View article: Global epidemiology, viral evolution, and public health responses: a systematic review on Mpox (1958–2024)
Global epidemiology, viral evolution, and public health responses: a systematic review on Mpox (1958–2024) Open
Mpox has evolved from a regionally contained zoonotic disease to a global public health challenge. Enhanced surveillance, international collaboration, and targeted interventions in non-endemic regions are critical for mitigating future out…
View article: Screening of <i>Klebsiella pneumoniae</i> isolates reveals the spread of strong biofilm formers and class 1 integrons
Screening of <i>Klebsiella pneumoniae</i> isolates reveals the spread of strong biofilm formers and class 1 integrons Open
Aims Klebsiella pneumoniae is a Gram-negative bacterium that can colonize, penetrate, and cause infections at several human anatomical locations. The emergence of hypervirulent K. pneumoniae and its ability to evade the immune system and d…
View article: Epsilon-poly-l-lysine inhibits biofilm formation and aids dispersion in Acinetobacter baumannii
Epsilon-poly-l-lysine inhibits biofilm formation and aids dispersion in Acinetobacter baumannii Open
Acinetobacter baumannii is a prominent hospital-associated bacterium whose eradication is increasingly challenging due to its remarkable ability to resist antibiotics. The most common illnesses caused by antibiotic-resistant A. baumannii a…
View article: Clinical and multidrug resistance profile of blood stream infections in COVID-19 patients admitted in Intensive care unit of tertiary care hospital western India.
Clinical and multidrug resistance profile of blood stream infections in COVID-19 patients admitted in Intensive care unit of tertiary care hospital western India. Open
Introduction : Bacterial coinfections, especially blood stream infections (BSIs) are common complications of many viral infections that lead to significant causes of morbidity and mortality in critically ill patients. We aimed to determine…
View article: Molecular characterization of typing and subtyping of Staphylococcal cassette chromosome SCCmec types I to V in methicillin-resistant Staphylococcus aureus from clinical isolates from COVID-19 patients
Molecular characterization of typing and subtyping of Staphylococcal cassette chromosome SCCmec types I to V in methicillin-resistant Staphylococcus aureus from clinical isolates from COVID-19 patients Open
Background and Objectives: Methicillin resistance is acquired by the bacterium due to mecA gene which codes for pen- icillin-binding protein (PBP2a) having low affinity for β-lactam antibiotics. mecA gene is located on a mobile genetic el-…
View article: Draft Genome Sequence of <i>Aeromonas caviae</i> Isolated from a Newborn with Acute Haemorrhagic Gastroenteritis
Draft Genome Sequence of <i>Aeromonas caviae</i> Isolated from a Newborn with Acute Haemorrhagic Gastroenteritis Open
Savita Jadhav, Ujjayni Saha, Kunal Dixit, Anjali Kher, Sourav Sen, Nitin Lingayat, Vivekanand Jadhav, and Sunil Saroj. Microbiol. Biotechnol. Lett. 2023;51:217-21. https://doi.org/10.48022/mbl.2301.01003
View article: Molecular Characterization of Carbapenem-Resistant Acinetobacter baumannii with Special Reference to Carbapenemases: A Systematic Review
Molecular Characterization of Carbapenem-Resistant Acinetobacter baumannii with Special Reference to Carbapenemases: A Systematic Review Open
Carbapenemases are β-lactamase enzymes that hydrolyze a variety of β-lactams including carbapenem and belong to different Ambler classes (A, B, D). These enzymes can be encoded by plasmid or chromosomal-mediated genes. The major issues ass…
View article: Quality Assurance with Reference Quality Control Strains in Antimicrobial Susceptibility Testing: Need for Quality Antimicrobial-Resistant Research [Letter]
Quality Assurance with Reference Quality Control Strains in Antimicrobial Susceptibility Testing: Need for Quality Antimicrobial-Resistant Research [Letter] Open
Letter for the article Bacteriological Profiles, Antimicrobial Susceptibility Patterns, and Associated Factors in Patients Undergoing Orthopedic Surgery with Suspicion of Surgical Site Infection at Arba Minch General Hospital in Southern E…
View article: Berberine: Best Alternative Medicine Insight Abating Global Challenges for Treatment of MRSA Infections [Letter]
Berberine: Best Alternative Medicine Insight Abating Global Challenges for Treatment of MRSA Infections [Letter] Open
Savita Jadhav,1 Vivekanand Jadhav,2 Kalpana Angadi1 1Symbiosis Medical College for Women (SMCW) & Symbiosis University Hospital and Research Centre (SUHRC), Symbiosis International (Deemed University), Lavale, Pune, India; 2Dr. Naidu I…
View article: SIGNIFICANCE OF DETECTION OF FREE/TOTAL PSA RATIO AND OTHER BIOCHEMICAL PARAMETERS IN PATIENTS WITH BPH, CARCINOMA PROSTATE AND ITS CLINICOPATHOLOGIC CORRELATION
SIGNIFICANCE OF DETECTION OF FREE/TOTAL PSA RATIO AND OTHER BIOCHEMICAL PARAMETERS IN PATIENTS WITH BPH, CARCINOMA PROSTATE AND ITS CLINICOPATHOLOGIC CORRELATION Open
Background. Benign prostatic hyperplasia (BPH) can raise prostate-specific antigen (PSA) levels two to three times higher than the normal level. An increased PSA level does not indicate Prostate Cancer (PCa), but the higher the PSA level, …
View article: Evolutionary Dynamics Based on Comparative Genomics of Pathogenic Escherichia coli Lineages Harboring Polyketide Synthase ( <i>pks</i> ) Island
Evolutionary Dynamics Based on Comparative Genomics of Pathogenic Escherichia coli Lineages Harboring Polyketide Synthase ( <i>pks</i> ) Island Open
Extraintestinal pathologies caused by highly virulent strains of E. coli amount to clinical implications with high morbidity and mortality rates. Pathogenic E. coli strains are evolving with the horizontal acquisition of mobile genetic ele…
View article: Coexistence of <i>β</i>-Lactamases in Community-Acquired Infections in a Tertiary Care Hospital in India
Coexistence of <i>β</i>-Lactamases in Community-Acquired Infections in a Tertiary Care Hospital in India Open
Introduction . The trends of β -lactamases producing Enterobacteriaceae is ever increasing, and limited studies have reported investigating coexistence of β lactamases in Enterobacteriaceae . A cross-sectional study after approval from the…
View article: Molecular Genetic and Functional Analysis of pks-Harboring, Extra-Intestinal Pathogenic Escherichia coli From India
Molecular Genetic and Functional Analysis of pks-Harboring, Extra-Intestinal Pathogenic Escherichia coli From India Open
Colibactin, a genotoxin, encoded by the pks pathogenicity island of Escherichia coli belonging to the B2 phylogroup has been reported as a determinant of bacterial pathogenicity. The present study was carried out to detect th…
View article: EPIDEMIOLOGY OF ACINETOBACTER SPECIES IN A TERTIARY CARE HOSPITAL WITH SPECIAL REFERENCE TO SEASONAL VARIATION)
EPIDEMIOLOGY OF ACINETOBACTER SPECIES IN A TERTIARY CARE HOSPITAL WITH SPECIAL REFERENCE TO SEASONAL VARIATION) Open
ResultsDuring the study period, a total of 34,910 samples were processed and 8,905 isolates were obtained.Out of these isolates, 490 (5.5%) were Acinetobacter spp.In ward-wise distribution, the maximum number of isolates were obtained from…
View article: Whole-Genome Sequencing and Annotation of a Drug-Resistant Extrapulmonary Clinical Isolate of Beijing Genotype Mycobacterium tuberculosis from Pune, India
Whole-Genome Sequencing and Annotation of a Drug-Resistant Extrapulmonary Clinical Isolate of Beijing Genotype Mycobacterium tuberculosis from Pune, India Open
Whole-genome sequencing has emerged as a powerful tool to map genetic diversity among Mycobacterium tuberculosis isolates and identify the genomic signatures associated with drug resistance, pathogenesis, and disease transmission. Isolate …
View article: INCIDENCE AND ANTIMICROBIAL SUSCEPTIBILITY OF ENTEROCOCCAL INFECTIONS IN TERTIARY CARE HOSPITAL
INCIDENCE AND ANTIMICROBIAL SUSCEPTIBILITY OF ENTEROCOCCAL INFECTIONS IN TERTIARY CARE HOSPITAL Open
View article: FREQUENCY OF MUTATION IN ISONIAZID RESISTANT ISOLATES OF Mycobacterium tuberculosis COMPLEX FROM WESTERN MAHARASHTRA INDIA
FREQUENCY OF MUTATION IN ISONIAZID RESISTANT ISOLATES OF Mycobacterium tuberculosis COMPLEX FROM WESTERN MAHARASHTRA INDIA Open
View article: PHENOTYPIC DETECTION OF AmpC β-LACTAMASE PRODUCTION IN GRAM NEGATIVE CLINICAL ISOLATES
PHENOTYPIC DETECTION OF AmpC β-LACTAMASE PRODUCTION IN GRAM NEGATIVE CLINICAL ISOLATES Open
Background: Detection of AmpC β-lactamase producing isolates is needed to provide the accurate and effective treatment to patient for their better outcome.In laboratories test can be performed by simple phenotypic screening and confirmatio…
View article: Clinical Significance of Non-candidal Yeast like Genera with Special Reference to Trichosporon and Malassezia
Clinical Significance of Non-candidal Yeast like Genera with Special Reference to Trichosporon and Malassezia Open
Introduction: The incidence of opportunistic fungal infections is increasing world over. This is mainly due to increase in risk factors like prolonged antimicrobial use, prolonged catheterisations both urinary and vascular, increased patie…
View article: Comparative Genomic Analysis of Globally Dominant ST131 Clone with Other Epidemiologically Successful Extraintestinal Pathogenic <i>Escherichia coli</i> (ExPEC) Lineages
Comparative Genomic Analysis of Globally Dominant ST131 Clone with Other Epidemiologically Successful Extraintestinal Pathogenic <i>Escherichia coli</i> (ExPEC) Lineages Open
Escherichia coli sequence type 131 (ST131), a pandemic clone responsible for the high incidence of extraintestinal pathogenic E. coli (ExPEC) infections, has been known widely for its contribution to the worldwide dissemination of multidru…
View article: Comparative Genomics of <i>Escherichia coli</i> Isolated from Skin and Soft Tissue and Other Extraintestinal Infections
Comparative Genomics of <i>Escherichia coli</i> Isolated from Skin and Soft Tissue and Other Extraintestinal Infections Open
Escherichia coli , an intestinal Gram-negative bacterium, has been shown to be associated with a variety of diseases in addition to intestinal infections, such as urinary tract infections (UTIs), meningitis in neonates, septicemia, skin an…
View article: Molecular Epidemiology and Genome Dynamics of New Delhi Metallo-β-Lactamase-Producing Extraintestinal Pathogenic Escherichia coli Strains from India
Molecular Epidemiology and Genome Dynamics of New Delhi Metallo-β-Lactamase-Producing Extraintestinal Pathogenic Escherichia coli Strains from India Open
The global dissemination and increasing incidence of carbapenem-resistant, Gram-negative organisms have resulted in acute public health concerns. Here, we present a retrospective multicenter study on molecular characterization of metallo-β…
View article: Population structure and molecular epidemiology of human clinical multi-drug resistant (MDR) Escherichia coli strains from Pune, India
Population structure and molecular epidemiology of human clinical multi-drug resistant (MDR) Escherichia coli strains from Pune, India Open
Background: Extraintestinal pathogenic E. coli (ExPEC) cause different infectious diseases in humans and animals, accounting 80% of urinary tract infections (UTIs), worldwide. Increase in the prevalence of multidrug-resistant (MDR) E. coli…
View article: Sepsis 2016 Agra, India
Sepsis 2016 Agra, India Open
View article: Candidemia: Speciation and Antifungal susceptibility testing from a Tertiary Care Hospital in Maharashtra, India
Candidemia: Speciation and Antifungal susceptibility testing from a Tertiary Care Hospital in Maharashtra, India Open
Introduction: Invasive fungal infections are an important nosocomial health problem, candidal infections being the most common. Candidal bloodstream infections (BSIs) account for one-fourth of the nosocomial BSIs. Candida albicans once the…
View article: Genomic and Functional Portrait of a Highly Virulent, CTX-M-15-Producing <i>H</i> 30-Rx Subclone of Escherichia coli Sequence Type 131
Genomic and Functional Portrait of a Highly Virulent, CTX-M-15-Producing <i>H</i> 30-Rx Subclone of Escherichia coli Sequence Type 131 Open
Escherichia coli sequence type 131 (ST131) is a pandemic clone associated with multidrug-resistant, extraintestinal infections, attributable to the presence of the CTX-M-15 extended-spectrum β-lactamase gene and mutations entailing fluoroq…
View article: Isolation and identification of Acinetobacter species with special reference to antibiotic resistance
Isolation and identification of Acinetobacter species with special reference to antibiotic resistance Open
A high level of antibiotic resistance was observed in our study and maximum isolation rate of Acinetobacter was in the ICUs. Acb complex was the most predominant and most resistant species. The analysis of susceptibility pattern will be us…
View article: Occurrence of catheter-associated urinary tract infection in critical care units
Occurrence of catheter-associated urinary tract infection in critical care units Open
Background: Catheter-associated urinary tract infection (CAUTI) is the most common nosocomial infection. The etiological agents of which may be varied. Advancing age, debilitation, diabetes mellitus, duration of catheterization are the ris…