Vivek Kumar Morya
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View article: Outcome comparison of lower trapezius tendon transfer and arthroscopic rotator cuff tear repair using muscle advancement for massive rotator cuff tear: a systematic review
Outcome comparison of lower trapezius tendon transfer and arthroscopic rotator cuff tear repair using muscle advancement for massive rotator cuff tear: a systematic review Open
Background: This systematic review evaluates the clinical outcomes of two distinct, arthroscopic techniques for the surgical repair of massive rotator cuff tears; lower trapezius tendon (LTT) transfer and muscle advancement (MA).Methods: E…
View article: Molecular Crosstalk Between RUNX2 and HIF-1α in Osteosarcoma: Implications for Angiogenesis, Metastasis, and Therapy Resistance
Molecular Crosstalk Between RUNX2 and HIF-1α in Osteosarcoma: Implications for Angiogenesis, Metastasis, and Therapy Resistance Open
Runt-related transcription factor-2 (RUNX2) is an integral player in osteogenesis and is highly expressed in osteosarcoma. Emerging evidence suggests that aberrant RUNX2 expression is a key factor in osteosarcoma oncogenesis. Patients with…
View article: Outcome comparison of arthroscopic latissimus dorsi tendon transfer and muscle advancement for irreparable rotator cuff tear: a systematic review
Outcome comparison of arthroscopic latissimus dorsi tendon transfer and muscle advancement for irreparable rotator cuff tear: a systematic review Open
Purpose: To compare the clinical outcomes and complications between latissimus dorsi tendon transfer (LDTT) and muscle advancement (MA) for irreparable rotator cuff tears (IRCTs). Methods: A PRISMA-guided systematic review included 24 stud…
View article: Potentials of SGLT2 inhibitors in the treatment of diabetic rotator cuff diseases: a comprehensive review
Potentials of SGLT2 inhibitors in the treatment of diabetic rotator cuff diseases: a comprehensive review Open
Degenerative rotator cuff disease (RCD) is a common musculoskeletal condition that disproportionately affects individuals with diabetes mellitus, leading to pain, functional impairment, and a reduced quality of life. Emerging evidence sugg…
View article: Synergistic HDAC4/8 Inhibition Sensitizes Osteosarcoma to Doxorubicin via pAKT/RUNX2 Pathway Modulation
Synergistic HDAC4/8 Inhibition Sensitizes Osteosarcoma to Doxorubicin via pAKT/RUNX2 Pathway Modulation Open
Osteosarcoma is a highly aggressive bone malignancy, particularly challenging in metastatic cases, with a 5-year survival rate remaining under 30%. Although doxorubicin (doxo) is a standard first-line chemotherapeutic agent, its clinical u…
View article: A Narrative Review on the Double Pulley-Triple Row Technique for Large to Massive Rotator Cuff Repair
A Narrative Review on the Double Pulley-Triple Row Technique for Large to Massive Rotator Cuff Repair Open
Rotator cuff tears are common shoulder injuries that often necessitate surgical intervention, particularly when nonoperative treatments fail. Arthroscopic rotator cuff repair is the current gold standard; however, challenges, such as high …
View article: Double Pulley-Triple Row Technique for Arthroscopic Rotator Cuff Repair: A Technical Note
Double Pulley-Triple Row Technique for Arthroscopic Rotator Cuff Repair: A Technical Note Open
Arthroscopic rotator cuff repair is the gold standard for treatment, but current techniques have shortcomings, especially for larger tears. Single-row repairs often fail to fully restore the footprint, leading to high retear rates. Althoug…
View article: Synergistic Enhancement of Cauliflower Yield: Harnessing Phosphate-Solubilizing Bacteria and Nitrogen-Fixing Microbes for Sustainable Agriculture
Synergistic Enhancement of Cauliflower Yield: Harnessing Phosphate-Solubilizing Bacteria and Nitrogen-Fixing Microbes for Sustainable Agriculture Open
Cauliflower (Brassica oleracea var. botrytis) is a crucial cash crop predominantly consumed as a vegetable. High-yielding varieties are favored to maximize productivity and income, but they require substantial nutrients, leading to heavy r…
View article: Advancements in Therapeutic Approaches for Degenerative Tendinopathy: Evaluating Efficacy and Challenges
Advancements in Therapeutic Approaches for Degenerative Tendinopathy: Evaluating Efficacy and Challenges Open
Degenerative tendinopathy results from the accumulation of minor injuries following unsuccessful tendon repair during acute tendon injuries. The process of tendon repair is prolonged and varies between individuals, making it susceptible to…
View article: Arthroscopic-guided Release of Supraspinatus and Infraspinatus Muscles for Repair of Large-to-Massive Rotator Cuff Tear and Suprascapular Nerve Release
Arthroscopic-guided Release of Supraspinatus and Infraspinatus Muscles for Repair of Large-to-Massive Rotator Cuff Tear and Suprascapular Nerve Release Open
This technical note presents an all-arthroscopic technique designed to release and advance the supraspinatus and infraspinatus muscles in cases of massive posterosuperior rotator cuff tears involving the retracted muscles. The aim is to av…
View article: Isolation and Characterization of Aeromonas taiwanensis Strain for Simultaneous Production of Cellulase, Amylase, Pectinase, and Protease Enzymes
Isolation and Characterization of Aeromonas taiwanensis Strain for Simultaneous Production of Cellulase, Amylase, Pectinase, and Protease Enzymes Open
A study was conducted to discover a novel microorganism capable of producing multiple enzymes with industrial applications. Bacterial isolates were screened from a soil sample collected from a wood-decaying area, and their ability to produ…
View article: A Molecular Perspective on HIF-1α and Angiogenic Stimulator Networks and Their Role in Solid Tumors: An Update
A Molecular Perspective on HIF-1α and Angiogenic Stimulator Networks and Their Role in Solid Tumors: An Update Open
Hypoxia-inducible factor-1α (HIF-1α) is a major transcriptional factor, which plays an important role in cellular reprogramming processes under hypoxic conditions, which facilitate solid tumors’ progression. HIF-1α is directly involved in …
View article: Hypoxia-Inducible Factor and Oxidative Stress in Tendon Degeneration: A Molecular Perspective
Hypoxia-Inducible Factor and Oxidative Stress in Tendon Degeneration: A Molecular Perspective Open
Tendinopathy is a debilitating condition marked by degenerative changes in the tendons. Its complex pathophysiology involves intrinsic, extrinsic, and physiological factors. While its intrinsic and extrinsic factors have been extensively s…
View article: Application of ChatGPT for Orthopedic Surgeries and Patient Care
Application of ChatGPT for Orthopedic Surgeries and Patient Care Open
Artificial intelligence (AI) has rapidly transformed various aspects of life, and the launch of the chatbot "ChatGPT" by OpenAI in November 2022 has garnered significant attention and user appreciation. ChatGPT utilizes natural language pr…
View article: Computational Analysis of miR-140 and miR-135 as Potential Targets to Develop Combinatorial Therapeutics for Degenerative Tendinopathy
Computational Analysis of miR-140 and miR-135 as Potential Targets to Develop Combinatorial Therapeutics for Degenerative Tendinopathy Open
In this study, the association between miRNAs and the disease was evaluated to correlate the tendinopathy genes and the relevant role of different miRNAs in their regulation. Through this study, it was established that the synergistic effe…
View article: Profiling of Antifungal Activities from the Leaf Extract of Selected Apiaceae Family Plants against <i>Aspergillus fumigates</i>
Profiling of Antifungal Activities from the Leaf Extract of Selected Apiaceae Family Plants against <i>Aspergillus fumigates</i> Open
Many ethnic plants are used as a source of traditional medicine to cure a variety of illnesses in both humans and animals. Developing secondary metabolites in plants with antifungal characteristics, offer alternative medications for reason…
View article: Insights into multiple enzymes produced by an indigenously isolated novel Aeromonas veronii strain revealing diverse applications
Insights into multiple enzymes produced by an indigenously isolated novel Aeromonas veronii strain revealing diverse applications Open
In the quest for a novel microbe capable of producing multiple enzymes significant in industrial applications, bacterial isolates from soil samples collected from the wood-decaying area were screened. With this aim, the isolates were scree…